Protein Alignment Nepl20 and Nep4

DIOPT Version :10

• Sequence 1: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Alignment Length: 824
• Identity: 226/824 - (27%)
• Similarity: 351/824 - (42%)
• Gaps: 198/824 - (24%)

  Fly    37 KELMRQAKAAEIESFMNQKVDPCKDFYAFSCGNYKR----------------------------- 72
            :|.:|..:|..::.:|:.|||||.|||.::|||::|
  Fly   255 REGIRMTQAKTMKRYMDNKVDPCVDFYKYACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLL 319

  Fly    73 -----INSALNM---------------------------------------------RVLTTGVF 87
                 ::||..:                                             |||..  :
  Fly   320 EKNTPVHSAAELRKSPVRNTLFKLNEQGEGEGEADQAAELTAERLRRHIVSKRQLLNRVLVR--Y 382

  Fly    88 ETLTKGLNRKILKMLNTPH--------------------DSHDTPEDIQV--------------- 117
            :..|.|..||  :::.||.                    |..|..|.:.|
  Fly   383 KRYTNGTKRK--RLIETPRERTKEEEAAPPVVLPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKA 445

  Fly   118 KHFYESCLQIKELNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFDWLNTTARMAHRYGIMSIIGV 182
            |:.|.||:....|.....|.|..||.|.|..|:|| |.|.|.:|:| ...|....||....:|..
  Fly   446 KNLYRSCVNSAVLAKRGLEPLHTLIRELGGWPVLE-SQWSESNFNW-QVLAATLRRYNNDILIVQ 508

  Fly   183 GVATDFANNQKNIIYINQQEFPLKTRSMYMDNETAIYRQNYQNNIQLILEKYLGVKDELARKAAK 247
            .|..|..|:::||:..:|....|.||..::....|.|.|.||..:..::.| :|.....|::.|.
  Fly   509 WVGADIKNSEENIVQFDQTGLGLPTREYFLQPSNAKYLQAYQRYMAEVMHK-MGASKADAQRVAS 572

  Fly   248 EMFEFEVDLAHGLVDNNKHLNLRDLIELLTVAELR--------ERYAPTLDTDQLIFVSMGEKIS 304
            |:..||..||.......:.||:..|.:.:|:.:|:        ..|..:|...:::.       :
  Fly   573 ELVAFETQLAGITAPAEQRLNVTKLYKRMTLDQLQAVVPEIKWRAYLQSLQDREVLG-------T 630

  Fly   305 DKVYEYNRRYQQNLVEVIERTPKSTVANYLFLRLIWEFIQ-------------KPS------GVA 350
            ::|..|...|...||.:::.|...||:||    ::|.|::             |.|      |..
  Fly   631 EEVVIYAVEYMSKLVTLLDETDPRTVSNY----MMWRFVRHRINNVDDRFDDIKQSFYHALFGRE 691

  Fly   351 EKPT--EACVDFTKTYFAKNLDNMIYRRYKNEKSSREIDSMWHQLKSTFKETLLSSPALDWIEPS 413
            |.|.  :.|:....|.....:.:|...||.:..|.|:...|.|.|:..|::.|.::   ||::.:
  Fly   692 ESPQRWKVCIAQVNTNMGMAVGSMFVSRYFDNNSKRDTLRMTHDLQQAFRDILKTT---DWLDDT 753

  Fly   414 TRSLAIAKLEAMTLEVN--NYV--KENFTEEFADLNLQNTDCVENLRQVQMLQAKQMRQLYHQ-- 472
            |:.||..|:.||:|::.  :::  ......::|.:.:......||...|.:..||..:...|:
  Fly   754 TKQLAEEKVNAMSLKIGYPDFILNPSELNSKYAGIEIYPEKYFENTLNVLLHTAKTEQAKLHERV 818

  Fly   473 --------PAKPLEAGELLSYTPSNILLENSIKVPVALLQ-PFYIWSDVYPNAVMFGTLAYLIGH 528
                    ||      .:.:|...|   :|.|..|..:|| |||  ...:|.::.||.:..:|||
  Fly   819 NKTNWQTAPA------IVNAYYSRN---KNQIMFPAGILQPPFY--HRHFPKSLNFGGIGVVIGH 872

  Fly   529 ELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYD--GIQLKESTAQSENIA 591
            ||.|||||.||.||..||...||.:.|...|.:|..|...||..|..:  ||.|...:.|.||||
  Fly   873 ELTHGFDDKGRLFDRNGNIHKWWTDSSIRGFDERARCIIAQYSNYTVEEVGIVLNGESTQGENIA 937

  Fly   592 DNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWCNDVHPKVKALQ 656
            ||||:|.|:.||::|      |.....:::.|.||.|..|..||||::|.|.||..:.|:....:
  Fly   938 DNGGLRQAFHAYQRW------LKEHPSEVSDEILPGLNMTGPQLFFLNFGQVWCGAMRPEAIRNK 996

  Fly   657 VSTDDHMPGKFRVIGTLSNFEEFSKEFNCHAGSAMNPIEKCILY 700
            ::|..|.||:|||||||||..:|::||||..||.|||.:||.::
  Fly   997 LNTAIHSPGRFRVIGTLSNSVDFAREFNCPLGSPMNPQKKCSVW 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl20	NP_651645.1	M13	56..697	CDD:341056	219/800 (27%)
Nep4	NP_650904.3	M13	274..1038	CDD:341056	220/801 (27%)