Protein Alignment Nepl20 and Nepl6

DIOPT Version :10

• Sequence 1: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 762
• Identity: 171/762 - (22%)
• Similarity: 307/762 - (40%)
• Gaps: 176/762 - (23%)

  Fly     8 IWIASHVLSVLVLAAPTSEDVLNQDTPYMKELMRQAKAAEIESFMNQKVDPCKDFYAFSCGNYKR 72
            :|:.:.:..|.:.||||:::|   :......||.     .|.|::.:....|..::.::||.|
  Fly     1 MWLIACLFIVPICAAPTTQNV---EADPNSRLMN-----NILSYVAEDSSACGTYFQYACGKY-- 55

  Fly    73 INSALNMR-VLTTGVFETLTKGLNRKILKMLNTPHDSHDTP------EDIQVKHFYESCLQIKEL 130
               |:..| ...|.:.:.|...:|..::::::..|....:|      .:.:|.|||.:|.:....
  Fly    56 ---AVRHRDDPFTEIIQMLDHKVNGNLVQLMHELHQRSQSPGFNESSVEAKVLHFYRTCREAPPS 117

  Fly   131 NSTYSEKLKRLIAEFG---TMP--LLEGSSWQEDDFDWLNTTARMAHRYGIMSIIGVGVATDFAN 190
            .......|:  :|..|   |.|  :..|..|.:..|.|:.:...: :|||            |.|
  Fly   118 TRKMEHYLR--LAPPGQALTWPQFMPRGEPWPKAQFKWMKSLGHL-YRYG------------FTN 167

  Fly   191 NQKNIIYI----NQQEFPLKTRSMYMDNETAIYRQNYQNNIQLILEKYLGVKDE----LARK--- 244
            ...|::.:    |...|.|......::.: |.:...:.:.:..:  :.:||..:    |.||
  Fly   168 VLVNVLVLRSSENSNRFRLDISMPSLEGD-AQHLGGFLSTLATL--QIIGVPTKSILPLVRKIRR 229

  Fly   245 ---AAKEMFEFEVDLAHGLVDNNKHLNLRDLIELLTVAELRERYAPTLDTDQLIFVSMGEKISDK 306
               |.:.:.|.:.|      |.::...||..       |.:..||.....:.::    |..:|
  Fly   230 LESAIRVLTEVDDD------DESETWTLRQW-------EYKTGYAWQGFVESIV----GHSVS-- 275

  Fly   307 VYEY-----NRRYQQNLVEVIERTPKSTVANYLFLR----LIWEFIQKPSGVAEKPTEACVDFTK 362
             :.|     |.:|...|..:::.|....||||:..|    ||.:||.....:      .||
  Fly   276 -HHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVLYLIDDFIDSNEHI------DCV---- 329

  Fly   363 TYFAKNLD---NMIYR-RYKN----EKSSREIDSMWHQLKSTF----KETLLSSPALDWIEPSTR 415
            |...:|::   |::|: |:.:    ::.::|:..::.||:..|    .|..|.      :.....
  Fly   330 TDMRRNMNLASNLLYKERFLDPATLQQYTQEVTKVFEQLRRQFLLQINENRLG------LTSEQN 388

  Fly   416 SLAIAKLEAMTLEVNNYVKENFTEEFADLNLQNTDCV----------ENLRQVQMLQAKQMRQLY 470
            |:...|.:.:.|.:.|..:......|...:.:  |.|          |:|..::....||:.||.
  Fly   389 SMVATKAQHVVLNIGNLPRGRDHRSFVSRHYE--DLVFPLPDFDYAREHLNLLEFRTRKQVLQLN 451

  Fly   471 HQPAKPLEAGEL------LSYTPSNILLENSIKVPVALLQ-PFYIWS--DVYPNAVMFGTLAYLI 526
            .....|.|...|      :|..|..::..|.|.||..||| ||:...  |::    .:..|.:::
  Fly   452 QSAPTPDEFFYLSDPKTAMSSGPYYLMRLNIIVVPHGLLQEPFFAADSHDIF----KYSLLGFVL 512

  Fly   527 GHELIHGFDDSGRKFDEKGNSKDWWDEKSSS-NFLKRRDCFTKQYGRYVYDGIQLKESTAQSENI 590
            .|||:|..|..|..:|..||..:...:.||| .|:....|..:...:|:            .|.|
  Fly   513 AHELMHSVDTVGLYYDRYGNIHEIGPQISSSPRFVAGLQCLNRNSTQYL------------DERI 565

  Fly   591 ADNGGMRLAYTAYRKWYEN--QLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWCNDVHPKVK 653
            ||..|:.|||:.|   ::|  |::|    .|.|  |:|     .:|:||::.||.:|.|..|
  Fly   566 ADIAGLDLAYSTY---FQNSSQMSL----TDFT--TIP-----PQQIFFLNLAQFFCGDGDP--- 613

  Fly   654 ALQVSTDDHMPGKFRVIGTLSNFEEFSKEFNCHAGSAMNPIEKCILY 700
               ::...|...:.|:...|:.|..|.:.|.|.|.|  |..|||.|:
  Fly   614 ---INFVGHDNDETRLQQMLNGFAPFHEAFGCPAKS--NQPEKCQLW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl20	NP_651645.1	M13	56..697	CDD:341056	157/709 (22%)
Nepl6	NP_609023.3	M13	47..653	CDD:341056	157/704 (22%)