Protein Alignment Nepl20 and Nep1

DIOPT Version :10

• Sequence 1: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_511056.2
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Alignment Length: 750
• Identity: 201/750 - (26%)
• Similarity: 348/750 - (46%)
• Gaps: 89/750 - (11%)

  Fly     8 IWIAS-HVLSVLVLAAPTSEDVLN-------------QDTPYM-KELMRQAKAAEIESFMNQKVD 57
            |:.|| |....|....|.::|..|             ||...| :|.:|  .||.:.|.|:...|
  Fly   132 IYFASVHQRCHLYRLEPDNDDRPNGRWNQDSGSAHEGQDNICMTQECVR--TAASLLSAMDLNSD 194

  Fly    58 PCKDFYAFSCGNYKRINSALNMRVLTTGVFETLTKGLNRKILKMLNTPHDSHDTPEDIQVKHFYE 122
            ||:||:.::||.:.:::.....| .:...||.|:......:..:|..|.|..|....|:.|.|::
  Fly   195 PCEDFFQYACGTWNKMHPIPEDR-SSISTFEVLSDQQQVILRAVLEEPIDERDNKATIKAKTFFK 258

  Fly   123 SCLQIKELNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFDWLNTTARMAHRYGIMSIIGVGVATD 187
            ||:.|.::....:.:||:::...|..|::|.:.....|........::...|....:|.:.|..|
  Fly   259 SCMDIPQIRKIGTGRLKQVLQSLGGWPVIERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGAD 323

  Fly   188 FANNQKNIIYINQQEFPLKTRSMYMDNETAIYRQ---NYQNNIQLILEKYLGVKDELARKAAKEM 249
            ..|:..||:.::|.::.|.:|..|:...:|..|:   .|...:.|:    ||.....|....:::
  Fly   324 DKNSSVNILQMDQLQYALPSRDYYLKESSANDRRAYHRYMTQVALL----LGADPATAAAELEKV 384

  Fly   250 FEFEVDLAH-GLVDNNKH---LNLRDLIELLTVAELRERYAPTLDTDQLIFVSMGEKI----SDK 306
            ..||..|.: .|.:.::|   |..|.::    :.||:| ..|.:...:.:..::|..|    .:.
  Fly   385 VLFETQLVNVSLPEADRHDTSLVYRKML----LPELQE-LVPEVQWQEYLQAALGPGIPLQEDEP 444

  Fly   307 VYEYNRRYQQNLVEVIERTPKSTVANYLFLRLIW---------------EFIQKPSGVAEKPT-- 354
            :..|...|...:.:::..|.:..|.||:..||:.               ||.:...|:..:.|
  Fly   445 LVTYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRW 509

  Fly   355 EACVDFTKTYFAKNLDNMIYRRYKNEKSSREIDSMWHQLKSTFKETLLSSPALDWIEPSTRSLAI 419
            ..||::|.......:..:..|...|::|......|.|.:::.|.|.|..:   ||::..||::|.
  Fly   510 SQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNELLAEN---DWMDDETRAVAK 571

  Fly   420 AKLEAMTLEVNNY--VKENFTE---EFADLNLQNTDCVENLRQVQMLQAKQMRQLYHQP------ 473
            .|.::|...: .|  :..|.||   |:.:|.:...:.:.|:..:...::::|.:|..||
  Fly   572 EKADSMNERI-GYPELLTNATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKW 635

  Fly   474 -AKPLEAGELLSYTPSNILLENSIKVPVALLQPFYIWSDVYPNAVMFGTLAYLIGHELIHGFDDS 537
             .:|......  |.|:    :|.|..|..:|||.: :|..:|.::.:|.:..:||||:.|||||.
  Fly   636 TTEPAVVNAF--YNPN----KNDIVFPAGILQPLF-YSQHFPKSLNYGGIGVVIGHEITHGFDDK 693

  Fly   538 GRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYDGIQ--LKESTAQSENIADNGGMRLAY 600
            ||:||::||...||:..:...|.:|..|...||.||..:.:.  :.....|.||||||||::.|:
  Fly   694 GRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAF 758

  Fly   601 TAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWCNDVHPKVKALQVSTDDHMPG 665
            .||:||.    ||....|.     ||.|..|..||||:::||.||..:.|:....::.:..|.||
  Fly   759 RAYKKWE----TLHGREQQ-----LPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPG 814

  Fly   666 KFRVIGTLSNFEEFSKEFNCHAGSAMNPIEKCILY 700
            ..||:|.|||..:|:..:.|..||.|||.|||.::
  Fly   815 FVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl20	NP_651645.1	M13	56..697	CDD:341056	182/682 (27%)
Nep1	NP_511056.2	M13	194..847	CDD:341056	183/682 (27%)