Protein Alignment Nepl20 and frma

DIOPT Version :9

• Sequence 1: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 714
• Identity: 151/714 - (21%)
• Similarity: 280/714 - (39%)
• Gaps: 162/714 - (22%)

  Fly    38 ELMRQAKAAEIESFMNQKVDPCKDFYAFSCGNYKRINSALNMRVLTTGVFETLTKGLN----RKI 98
            ||:......:::|  :.:.|||::||..:|||:...::        |..:|:....|:    .|:
  Fly     9 ELIVGLLVVQVKS--HPQADPCQNFYKVACGNWSASHA--------TDSYESFMDRLDYNYQEKL 63

  Fly    99 LKMLNTPHDSHDTPEDI-QVKHFYESCLQIKELNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFD 162
            ..:|:...:. |.|..: |:::||.:|.  |.|:   .:::.|::.....|..::.....
  Fly    64 ADLLDNERED-DEPHFLQQLRNFYTACR--KPLS---QDQVLRILEHLIVMENIQNEELS----- 117

  Fly   163 WLNTTARMAHRYGIMSIIGVGVATDFANNQKNIIYINQQEFPLKTRSMYMDNETAIYRQNYQNNI 227
                       .|:.:...:.|..|.  |..|...|.:|   |.:...:.|..|.       |..
  Fly   118 -----------VGLTAAFRLQVLIDL--NDSNTYDIWKQ---LMSHRKHWDPNTT-------NRE 159

  Fly   228 QLILEKYLGVKDELARKAAKEMFEFEVDLAHGLVDNNKHLNLRDLIELLTVAELRER---YAPT- 288
            .|..|.:    |:|.....|..|.|            |....|:|      :||.|:   |...
  Fly   160 PLTREMF----DKLWASLPKIPFPF------------KEYYWREL------SELEEKIMSYGSED 202

  Fly   289 --LDTDQLI-----FVSMGEKISDKVYEYNRRYQQNLVEV---IERTPKSTVANYLFLR--LIWE 341
              .|:..|:     |..|.....:..||       ||.::   ::......:..|:::|  |:.|
  Fly   203 DGFDSGDLVTRIPPFWMMPWPNGNITYE-------NLSQMAHWLDIKANEFILTYIYMRLKLVAE 260

  Fly   342 FIQKPSGVAEKPTEACVDFTKTYFAKNLDNMIYRRYKNEKSSREIDSMWHQLKSTFKETLLSSPA 406
            .:...|...::  :.|.:.::...:.....::.:.:...|....:..::.:||..|.:.||::
  Fly   261 GVSTESWHIDR--DQCAEQSRQILSHPAAWLVEKNHPRLKEEPVLQDIFAELKQRFGQKLLAN-- 321

  Fly   407 LDWIEPSTRSLAIAKLEAMTLEVNNYVKENFTE--------EFADLNLQNTDCVENL-------- 455
            .:....||:...:.||:.|.|.::...:.:..:        .:.|:::..:|...||
  Fly   322 RNNFTRSTQHFLLGKLKRMRLRLSILPRNSSAQSMVRRIERHYRDVHMNASDYFGNLHIGLNHSR 386

  Fly   456 ---RQVQMLQAKQMRQLYHQPAK-------PLEAGELLSYTPS-NILLENSIKVPVALLQ-PFYI 508
               :..|:......|||.  |::       |.:.....:|..: .|:.:|.:.||::||: |||.
  Fly   387 SHKKYAQLWAIVFGRQLI--PSRISKSDLYPTQVRGYGTYASAFYIVKQNMLIVPLSLLEPPFYT 449

  Fly   509 WSDVYPNAVMFGTLAYLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSN--FLKRRDCFTKQYG 571
            ...  |:.:.:..|.:::||||.||||..|..|...|......|.:...|  |.:...|..:::|
  Fly   450 HGQ--PSILTYSALGFILGHELSHGFDSEGMTFSSHGVGSSAVDRELDRNPRFQQELGCLRRRFG 512

  Fly   572 RYVYDGIQLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLF 636
            |..|            |..||..|:.|||:||....:........|:::.         |.||.|
  Fly   513 RKRY------------EKFADASGLELAYSAYFDTAQTDHKRNRSAEELV---------TQKQQF 556

  Fly   637 FISFAQSWCNDVHPKVKALQVSTDDHMPGKFRVIGTLSNFEEFSKEFNCHAGSAMNPIEKCILY 700
            |.:|||.:|:|     |.| :...||...:.||...:::||.|.:.|:|......   .:|.||
  Fly   557 FHNFAQFFCSD-----KEL-LQAHDHGSDRKRVNDAVAHFEPFREAFSCGPSPRR---RQCRLY 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl20	NP_651645.1	PepO	50..691	CDD:226118	146/691 (21%)
		M13	56..697	CDD:189000	145/691 (21%)
frma	NP_572226.2	GluZincin	25..601	CDD:301352	145/681 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454907
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940