Protein Alignment Nepl20 and nep-25

DIOPT Version :10

• Sequence 1: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_495164.2
• Gene: nep-25 / 191543
• WormBaseID: WBGene00022874
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 511
• Identity: 108/511 - (21%)
• Similarity: 181/511 - (35%)
• Gaps: 139/511 - (27%)

  Fly   243 RKAAKEMFEFEVDLAHGLVDNNKHLNLRDLIELLTVAELRERYAPTLDTDQLIFVSMGEKISDKV 307
            ||...:..:|:.:.|..:.:..|.||         :.:|:....|:.......|:|
 Worm    75 RKKHPKFDKFKGEDAFAIAEALKQLN---------IEQLKSECKPSKPRLSSFFIS--------- 121

  Fly   308 YEYNRRYQQNLVEVI----ERTPKSTVANYLFLRLIWEFIQKPSGVAEKPTEACVDFTKTYFAKN 368
             ..:.|..:|:.||:    |..|....|         ..|.|..|..|..|.     |::.....
 Worm   122 -AQDNRTIENVDEVLFPGFENYPCEEKA---------AIIIKEVGEIEDYTT-----TRSVLVSA 171

  Fly   369 LDNMIYRRYKNEKSSREIDSMWHQLKSTFKETLLSSPALDWIEPSTRSLAIAKLEAMTLEVNNYV 433
            ::..|..:.. ||...:...::::.||...:.::.:|   |.:         ..:|    :..||
 Worm   172 VNGFITSKLV-EKLDVKARKLFNKFKSVISKEIIKTP---WAK---------NYKA----IEQYV 219

  Fly   434 K--ENFT-EEFADLNLQNTDCVENLRQVQMLQAKQMRQLYHQPAKPL--------EAGELLSYTP 487
            :  .|.| ..|||:.:.....:|.....:....|::...:.||...|        :|.|||....
 Worm   220 EALSNITFRTFADVRITVKKSMELYESTEKDCRKKLDVAFSQPTAELVCKGVATRKAEELLDEPI 284

  Fly   488 SNIL-----------------LENSIKVP---VALLQPFYIWSDVYPNAVMFGTLAYLIGHELIH 532
            .:|.                 .:||:.:.   :.||...| :||:|      |::.:.:.||::|
 Worm   285 EDIFPQDQAGILKDVWQMFNSFDNSVYIGNEFLLLLNTDY-FSDLY------GSIGFSMIHEIMH 342

  Fly   533 G--FDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGR------YVYDGIQLK----ESTA 585
            .  |||:..   :|..||.|         .|..||...|..:      .|.:...:|    .:..
 Worm   343 TLVFDDNDL---DKPLSKLW---------TKNADCVKDQALKTCETFPTVTEMHNMKPACNTTVT 395

  Fly   586 QSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTA---KQLFFISFAQSWCN- 646
            ..|:.||....|:|:..|...|..:..:||              |.|   |||||...|..:||
 Worm   396 FEEDAADLAAYRIAWRIYENSYARKTVVPN--------------YEALDKKQLFFYGAAVFFCNQ 446

  Fly   647 DVHPKVKALQVSTDDHMPGKFRVIGTLSNFEEFSKEFNCHAGSAM--NPIEKCILY 700
            |...:|....::   |.....||...:|..::||..|.|.....|  |..:.|.||
 Worm   447 DGMSRVPFQNLA---HSNNYQRVNSLMSQMKQFSDAFKCKPTDKMITNRAKHCELY 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl20	NP_651645.1	M13	56..697	CDD:341056	105/506 (21%)
nep-25	NP_495164.2	Peptidase_M13	308..496	CDD:279739	56/223 (25%)