Protein Alignment Nepl20 and nep-24

DIOPT Version :10

• Sequence 1: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 609
• Identity: 126/609 - (20%)
• Similarity: 227/609 - (37%)
• Gaps: 145/609 - (23%)

  Fly    23 PTSEDVLNQDTPYMKELMRQAKAAEIESFMNQKVDPCKDFYAFSCGNYKRINSALNMRVLTTGVF 87
            |.:.:|.|  ||....|     |..:.::.:..||||.:|:.|:||......        |..::
 Worm    32 PATRNVCN--TPACITL-----AHMLHNYHDPSVDPCDNFHQFACGREHEHE--------TEDIY 81

  Fly    88 ETLTKGLNRKILKMLNTPHDSHDTPEDIQVKHFYESCLQIKELNSTYSEKLKRL------IAEFG 146
            ...||.:|..:.:.|.....|....|: .::..|::|..: |.|||.|.. |.|      |...|
 Worm    82 TKKTKTINNIMKRFLKKNETSRSKSEN-AMRTLYKACKTL-EKNSTASRN-KALQDIFQDIQSIG 143

  Fly   147 TMPLLEGSSWQEDDFDWLNTTARMAHRYGIMSIIGVGVATDFANNQKNIIYINQQEFPLKTRSMY 211
            ..|::: ..|.|..|| ||                     ||.   .|::.:.::.|.|...:.|
 Worm   144 AWPVVD-DKWDESKFD-LN---------------------DFL---VNLVRLGRKNFGLFQMARY 182

  Fly   212 MD------NETAIYRQNYQNNIQLILEKYLGVKDELARKAAKEMFEFEVDLAHGLVDNNKHLNLR 270
            ::      ...|.:|.|..          ||       |...|:.:     |:.:..|||.| |.
 Worm   183 VNVRNFAIGPEAAWRHNVD----------LG-------KTISEILK-----ANSVQTNNKKL-LD 224

  Fly   271 DLIELLTVAEL-----------------RERYAPTLDTDQLIFVSMGEKISDKVYEYNRRYQ--- 315
            ||.|.:.:.:.                 |..:..:::..:|:...|.   .||...:...||
 Worm   225 DLAEYVNLEKALSQHKFNTVQPGYIFSERSDFVSSVNFSRLVLEMMS---PDKRTLFPEVYQIMY 286

  Fly   316 -----------QNLVEVIERTPKSTVANYLFLRLIWEFIQKPSGVAE----KPTEACVDFTKTYF 365
                       .||..:|..|.|..:|||    ||::||.  :.:|:    .|:..|......:.
 Worm   287 LTNTSLFFGKNNNLETIIRNTSKRALANY----LIFKFID--TSIADLTYGSPSAFCEQKVINFL 345

  Fly   366 AKNLDNMIYRRYKNEKSSREIDSMWHQLKSTFKETLLSSPALDWIEPSTRSLAIAKLEAMTLEVN 430
            .:......||.:.::::.::|..:   .::|..:.|....|.||:...::.:|:.::.:|.:.:.
 Worm   346 PRAALRAFYRNFISKENRKKITKL---TEATQVQLLKIIGATDWMSIKSKKIAMDRVSSMNMVIG 407

  Fly   431 --NYVKE--NFTEEFADLNLQNTDCVEN-LRQVQMLQAKQMRQLY--HQPAKPLEAGELLSYTPS 488
              :|...  .....|..|||.::|.... :|::.....:|....|  ..|..||..|.:.:
 Worm   408 YPDYFDPPGKLDGLFEHLNLSSSDTYYTVVRKINRFMREQEMDYYTGEVPYYPLFPGLMTN---- 468

  Fly   489 NILLENSIKVPVALLQPFY---IWSDVYPNAVMFGTLAYLIGHELIHGFDDSGRKFD-EKGNSKD 549
              .:.|:....:.:..||:   .:...:|:.......:..:.||:.|.|  |....| ..|.::.
 Worm   469 --AMYNANDNNLMIFAPFFDDPFFDSSFPDYANIAFTSNTLAHEMGHTF--SPHLMDIMTGTTEV 529

  Fly   550 WWDEKSSSNFLKRRDCFTKQYGRY 573
            |...|.:..:.||..|...||..|
 Worm   530 WLTPKETEEYEKRVKCLEDQYTEY 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl20	NP_651645.1	M13	56..697	CDD:341056	119/576 (21%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:472708	119/576 (21%)