DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nepl20 and nep-15

DIOPT Version :9

Sequence 1:	NP_651645.1	Gene:	Nepl20 / 43412	FlyBaseID:	FBgn0039613	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_001257056.2	Gene:	nep-15 / 185513	WormBaseID:	WBGene00018227	Length:	267	Species:	Caenorhabditis elegans

Alignment Length:	231	Identity:	59/231 - (25%)
Similarity:	92/231 - (39%)	Gaps:	49/231 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   486 TPSNIL---LENSIKVPVALLQPFYIWSDVYPNAVMFGTLAYLIGHELIHGF--DDSGRK----F 541
            :|.|::   |:| :...:...|....|:.:   .::.|...:.:|||:.|.|  :.||..    |
Worm    51 SPRNLMATALKN-LTYELRQKQADLFWNHI---TLVLGFTGFSVGHEIGHSFFANHSGTDILPYF 111

  Fly   542 DEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYDGIQLKESTAQSENIADNG----GMRLAYTA 602
            .|...........|:.|..|...|.|:                  :|.:.|||    |::|||..
Worm   112 SENVEKCVQNQFNSTCNEYKEESCVTR------------------NEMLDDNGADIFGLQLAYKL 158

  Fly   603 YRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWCNDVHPKVKALQVST-DDHMPGK 666
            ..|:...:|          :|.:..|..|.:||||.|||..:|:....||...:... |.|....
Worm   159 MEKYLSGRL----------EERIERLNVTQEQLFFYSFANQFCSGSLSKVFIEEEGDYDPHSVNN 213

  Fly   667 FRVIGTLSNFEEFSKEFNCHAGSAM--NPIEKCILY 700
            .|| ..::....|.|.|||...|.|  :..|:||:|
Worm   214 VRV-NAVAQHPGFRKAFNCPDNSRMMKSATEQCIIY 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nepl20	NP_651645.1	PepO	50..691	CDD:226118	54/218 (25%)
Nepl20	NP_651645.1	M13	56..697	CDD:189000	56/226 (25%)
nep-15	NP_001257056.2	GluZincin	<87..237	CDD:387391	47/178 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910