Protein Alignment Nepl20 and nep-10

DIOPT Version :10

• Sequence 1: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_494532.2
• Gene: nep-10 / 173684
• WormBaseID: WBGene00017555
• Length: 711
• Species: Caenorhabditis elegans
• Alignment Length: 787
• Identity: 181/787 - (22%)
• Similarity: 297/787 - (37%)
• Gaps: 174/787 - (22%)

  Fly     4 KLFCIWIASHVLSVLVL----------------AAPT--SEDVLNQDTPYMKELMRQAK------ 44
            ||...||| ..|::|:|                .||.  |:|.|.:..|..|.....::
 Worm     9 KLSSPWIA-FALNLLLLIVFLALVTVHIKMTIDVAPVFKSDDPLPRGDPDQKPATIDSETQTVDE 72

  Fly    45 -------------AAEIESFMNQKVDPCKDFYAFSCGNYKRINSALNMRVLTTGVFETLTKGLNR 96
                         |.|:.::.:..||||:|||...||.:.. :||:....:.| ...||:|.:..
 Worm    73 PRNVCESPECITLAHELHNYKDPSVDPCQDFYQHFCGKFYE-HSAIGQGRMAT-KRSTLSKLIRE 135

  Fly    97 KILKMLNTPHDSHDTPEDIQVKHFYESCLQ---IKELNSTYSEKLKRL---IAEFGTMPLLEGSS 155
            .:||...:...|.:|     :|..|..|.:   |.:|||...:.|..:   |.:.|..|:|: ..
 Worm   136 FLLKNKTSTSKSENT-----MKQVYAKCRELQKISDLNSIPPQALLDIFSDIKKIGAWPVLD-KD 194

  Fly   156 WQEDDFDWLNTTARMAHRYG------------------IMSIIGVGVATDFANNQKNIIYINQQE 202
            |....|: ||...|.....|                  |...:..||       ||:::.
 Worm   195 WDGSKFN-LNEMLRQLVNLGETHLGFFHFDFIARPYVLIKPPLKQGV-------QKSVLE----- 246

  Fly   203 FPLKTRSMYMDNETAIYRQNYQNNIQLILEKYLGVK-DELARKAAKEMFEFEVDLAHGLVDNNKH 266
               |...|.::.......|.:..::....|....:| |:|.|.:...:         ||:.:.:.
 Worm   247 ---KVVKMILEANEIKMDQGFSEDLDEYFELSNRIKIDKLPRTSRSIV---------GLLPDVRR 299

  Fly   267 LNLRDLIELLTVAELRERYAPTLDTDQLIFVSMGEKISDKVYEYN-----RRYQQN-LVEVIERT 325
            :|.|.||..:.......|:..||              ..||..|:     |..:.| |..:|..|
 Worm   300 INFRGLILEMMPRSKMNRFLGTL--------------FQKVVTYHHPLFVRDNETNHLDTIIRST 350

  Fly   326 PKSTVANYLFLRLIWEFIQKPSGVAEKPTEACVDFTKTYFAKNLDNMIYRRYKNEKSSREIDSMW 390
            ....:||||....|...|:..:...:...|.|.........:....:..|...::.:..|:..:.
 Worm   351 SNRALANYLIFNFIHSSIKFLTFGLKSDRERCEKIVVQELPRPSLRVFMRNCVDKGNREEVAKLT 415

  Fly   391 HQLKSTFKETLLSSPALDWIEPSTRSLAIAKLEAMTLEVNNYVKENF------TEEFADLNLQNT 449
            ..:|....|.:..|   |...||.:...:.|:||:...:.  ..::|      .:|:.:|.|..:
 Worm   416 ETVKENVLEMIRES---DSFTPSVKKRVLKKVEAIGAIIG--YPDHFDPPGTLDKEYENLTLDAS 475

  Fly   450 DCVENLRQVQMLQAKQMRQLYHQPAKPLEAGELLSYTPSNILLE---------NSIKVPVALL-Q 504
            |....:.|       ::.||..|......||: ...:||:.:||         |::.|....| .
 Worm   476 DSYYKMSQ-------KLHQLRLQHQMEFLAGQ-TPLSPSDQVLEVNAHYDSKDNALTVLAPFLDD 532

  Fly   505 PFYIWSDVYPNAVMFGTLAYLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQ 569
            ||:  ...||..|......:|||||..|..|....:.|      .|:..:..:.:.||..|...|
 Worm   533 PFF--DSTYPEYVNLIFTGFLIGHEFGHSIDPKILRRD------GWYKTEDMTEYGKRAQCLIDQ 589

  Fly   570 YGRYVYD----GIQLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRY 630
            |..  ||    |.|:..:....|.:.|..|..:.:.|::|...:::....|.:|   :.|..|.:
 Worm   590 YDN--YDDPDHGKQMNGTYCIGEIVGDWVGRDVTWRAFKKMDLSKMQKLIGFED---KNLDQLYF 649

  Fly   631 TAKQLFFISFAQSWCNDVHPK-VKAL-QVSTDDHMPGKFRVIGTLSNFEEFSKEFNCHAGSAMNP 693
            ..:.|||       |.   |: :|:| |:.:|.|....|||.|..||..:|:|.|||..||.|||
 Worm   650 RIQSLFF-------CG---PRSMKSLEQLLSDPHPTEVFRVNGIYSNMPQFAKAFNCPIGSPMNP 704

  Fly   694 IEKCILY 700
            .:||.::
 Worm   705 EKKCKMF 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl20	NP_651645.1	M13	56..697	CDD:341056	162/693 (23%)
nep-10	NP_494532.2	M13	97..709	CDD:341056	163/694 (23%)