Protein Alignment Nepl20 and nep-9

DIOPT Version :9

• Sequence 1: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_494531.2
• Gene: nep-9 / 173683
• WormBaseID: WBGene00017554
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 715
• Identity: 152/715 - (21%)
• Similarity: 281/715 - (39%)
• Gaps: 146/715 - (20%)

  Fly    45 AAEIESFMNQKVDPCKDFYAFSCGNYKRINSALNMRVLTTGVFETLTKGLNRKILKMLNTPHDSH 109
            |.|::::.:.....|:|||..:|.|||...:....|....      .|.:|:.:...|.....:.
 Worm    73 AQELKAYSDTATKSCEDFYKATCENYKDHQALDRHRDCKK------RKAVNKLVRGFLQRDESTF 131

  Fly   110 DTPEDIQVKHFYESCLQIKELNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFDWLNTTARMAHRY 174
            .:..:..:|..:..|.::.. |::|.:..|. |.:.|:.|:|| .:|::..|:..:..|:
 Worm   132 TSESESAIKLIFGKCDELSR-NTSYLDIFKD-IKKIGSWPVLE-HNWKDSMFNLDDVIAK----- 188

  Fly   175 GIMSIIGVGVATDFANNQKNIIYINQQEFPLKTRSMYMDNETAIYRQNYQNNIQLILEKYLGV-- 237
                ::.:| :|||.            .|.|:.|.:...:.........:.||..:.:..||:
 Worm   189 ----LVKLG-STDFG------------LFKLELRKLAFGHFAVFVSSKQEQNIHQLEKTILGILK 236

  Fly   238 -----------KDELA-----RKAAKEMFEFEVDLAHGLVDNNKHLNLRDLIELLTVAELRERYA 286
                       .|:|.     :...||.::.|..:.:.|...:       ::|.|.::.|
 Worm   237 ANGIQQDRKELSDDLKDYSDFKNHLKEFYQEETYIEYRLYAGS-------IVENLGISSL----- 289

  Fly   287 PTLDTDQLIFVSMGEKISDKVYEYNRR-----------YQQNLVEVIERTPKSTVANYLFLRLIW 340
                |.|:...|.|..:.:.|   |:|           .:.||..:|::|||.|:||:    ||:
 Worm   290 ----TTQMALKSTGLDVFNHV---NQRTLITNSSLFFGEENNLGMIIQKTPKRTLANF----LIF 343

  Fly   341 EFIQKPSGVAEKPTEACVDFTKTYFAKNLDNMIYRRYKNEKSSREIDSMWHQLKSTFKETLLSSP 405
            .||...:......|:||.:.......:....::.|.:.||.:..::..|...||:...|.:.:||
 Worm   344 HFIDVMTTDLANATKACKETLIDLLPRASIQVLSRNFVNEDAQDDMVKMAQDLKTKITEMIDNSP 408

  Fly   406 ALD----WIEPSTRSLAIAKLEAMTLEVNNYVKENFTEEFADLNLQNTDCVENLRQVQMLQAKQM 466
            ...    ..:...:...|.|::|:.: |..|.:|....:|..|||..:|.:  .|.:|.|:..:.
 Worm   409 FFTKFHLVFDAEEQKKLIQKVKAIGI-VTEYPQEVLDRDFERLNLTPSDSI--YRTIQKLRRLRS 470

  Fly   467 RQLYHQPAKPLEAGEL-------LSYTPSNILLENSIKVPVALLQPFYIWSDVYPNAVMFGTLAY 524
            .||.......|:..:.       ...|.:|:    :|..|: :..|::..|  |||.|....:.:
 Worm   471 EQLIEHLGGDLDPTDTRVWGSAHYDQTTNNL----TIFAPI-IDGPYFDTS--YPNYVNQFLMGF 528

  Fly   525 LIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQY------------------G 571
            ::|.||....|....:.||||.:::|...:|...|.:...|:.::|                  |
 Worm   529 ILGRELGRSLDSVRIRKDEKGQTENWLKPESLKRFDEHLKCWAEKYDKSADPLKSESKGIRQIEG 593

  Fly   572 RYVYDGIQLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLR-YTAKQL 635
            ||:           |:|..||..|...::.|:.|     |.:.|      :|.|...: ...:::
 Worm   594 RYI-----------QNEMFADFIGHEASWRAFMK-----LDVKN------EEVLETFKVIKLRRM 636

  Fly   636 FFISFAQSWCNDVHPKVKALQVSTDDHMPGKFRVIGTLSNFEEFSKEFNCHAGSAMNPIEKCILY 700
            ||...|..:|.........|... :.|....|||.|...|..:|:..|.|.:...|||..||.::
 Worm   637 FFNVQALYFCRPPSGSTDWLSYQ-EHHQHYSFRVNGAFKNMPQFALAFECASDDDMNPQNKCSMF 700

  Fly   701  700
             Worm   701  700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl20	NP_651645.1	PepO	50..691	CDD:226118	145/699 (21%)
		M13	56..697	CDD:189000	148/699 (21%)
nep-9	NP_494531.2	M13	87..698	CDD:189000	149/697 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910