Protein Alignment Nepl20 and Nep4

DIOPT Version :10

• Sequence 1: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_061501026.1
• Gene: Nep4 / 1273777
• VectorBaseID: AGAMI1_013990
• Length: 1007
• Species: Anopheles gambiae
• Alignment Length: 806
• Identity: 231/806 - (28%)
• Similarity: 357/806 - (44%)
• Gaps: 167/806 - (20%)

  Fly    29 LNQD--TPYMKELMRQAKAAEIESFMNQKVDPCKDFYAFSCGNYKRIN------SALNMRVLTTG 85
            :|.|  :|   |.:|.|:.|.::.:|:...|||.|||.::|||:.|:|      :||:
Mosquito   235 MNDDRSSP---ESVRAAQVAIMKQYMDPDADPCDDFYQYACGNWDRVNPIPKDKAALD------- 289

  Fly    86 VFETLTKGLNRKILKML-------------NTPHDSHDTPE------------------------ 113
            .||.|.:.|: .:||.|             |........|:
Mosquito   290 TFELLRESLD-LVLKQLLLEGEPAGLLDVENALSTVRSQPDGTKKSTSTTTTAASAGWPTTTVTG 353

  Fly   114 ----------------------------------------------------DIQVKHFYESCLQ 126
                                                                :::.:|.:.||:.
Mosquito   354 GPAQQQLHRVRKRGRAENRNRSGRAVQNKLIIRSAQVKRVRRKRELLINDDAEMKARHLFVSCMN 418

  Fly   127 IKELNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFDWLNTTARMAHRYGIMSIIGVGVATDFANN 191
            .:.:.....|.|:.|:...|..|:||..:|.|..|||||.||.: .||....:|...|..|..|:
Mosquito   419 YELIERRGLEPLRTLLHSLGGWPVLEPHTWDESSFDWLNLTAAL-RRYNNDVLIVEWVGPDIKNS 482

  Fly   192 QKNIIYINQQEFPLKTRSMYMDNETAIYRQNYQNNIQLILEKYLGVKD---ELARKAAKEMFEFE 253
            .:||:..:|....|.||..|:......|.:.|:   |.:|| .:|:.|   :.||:|..||.|||
Mosquito   483 DENIVQFDQTSLGLPTRDYYLQPGNRKYLEAYR---QFMLE-VIGLLDVPADTARQATDEMIEFE 543

  Fly   254 VDLAHGLVDNNKHLNLRDLIELLTVAELRERYAPTLDTDQLIFVSMGEKI--SDKVYEYNRRYQQ 316
            ..||:......:..|:..|...|.:.:|:|. .|.::....:.:.....:  |..|..:...|.:
Mosquito   544 TQLANITSTPEERNNVSTLYRKLMLDQLQEE-VPQINWTHYLTIVTERPVNGSSFVVMFAMSYMR 607

  Fly   317 NLVEVIERTPKSTVANYLFLRLIWEFIQ--------KPSGVAEKPTEA-------------CVDF 360
            :|||:|::|....||||    |:|.|::        :..|..::.:.|             ||..
Mosquito   608 DLVELIDQTEPRIVANY----LLWRFVRHRINNLDDRFLGAKQRFSNALFGRERNPPRWKNCVTQ 668

  Fly   361 TKTYFAKNLDNMIYRRYKNEKSSREIDSMWHQLKSTFKETLLSSPALDWIEPSTRSLAIAKLEAM 425
            ........:..|..|||.:|.|.|:..:|.|:|:..|:|.|   ....||:.:||.||..|:.||
Mosquito   669 VNANMGMAVGAMFVRRYFDENSKRDTLTMTHELQDAFREIL---GRTGWIDMATRQLAEQKVNAM 730

  Fly   426 TLEVN--NYV--KENFTEEFADLNLQNTDCVEN----LRQVQMLQAKQMRQLYHQPAKPLEAGEL 482
            :|.:.  :::  .|..:..:|.|.:......||    |..::....:::.|..::.|.......:
Mosquito   731 SLRIGYPDFILDPEQLSARYATLEIHPDRYFENTLNVLSHIRRTDQEKLGQPVNKTAWHTAPAVV 795

  Fly   483 LSYTPSNILLENSIKVPVALLQ-PFYIWSDVYPNAVMFGTLAYLIGHELIHGFDDSGRKFDEKGN 546
            .:|...|   :|.|..|..:|| |||  ....|.|:.:|.:..:|||||.|||||.||.||..||
Mosquito   796 NAYYSRN---KNQIMFPAGILQPPFY--HRHLPKAINYGGIGVVIGHELTHGFDDKGRLFDRDGN 855

  Fly   547 SKDWWDEKSSSNFLKRRDCFTKQYGRY--VYDGIQLKESTAQSENIADNGGMRLAYTAYRKWYEN 609
            ...||.:::...|.:|..|..:|||||  ....:||.....|.||||||||::.|:.||.||
Mosquito   856 LYRWWSDRAIEEFHERAACLVEQYGRYRIAEVDVQLDGENTQGENIADNGGIKQAFLAYSKW--- 917

  Fly   610 QLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWCNDVHPKVKALQVSTDDHMPGKFRVIGTLS 674
             |......:.:..||||.|..|..||||::|||.||..:.|:....::.|..|.||:||||||||
Mosquito   918 -LAAQTDRRVLEAETLPGLNVTRTQLFFLNFAQIWCGAMRPEATRNKLKTAVHSPGRFRVIGTLS 981

  Fly   675 NFEEFSKEFNCHAGSAMNPIEKCILY 700
            |.|:|::|::|..||.|||..||.::
Mosquito   982 NSEDFAREYHCPVGSTMNPPGKCSVW 1007

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl20	NP_651645.1	M13	56..697	CDD:341056	221/772 (29%)
Nep4	XP_061501026.1	None