Protein Alignment Nepl20 and ecel1

DIOPT Version :10

• Sequence 1: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_012818808.2
• Gene: ecel1 / 100496473
• XenbaseID: XB-GENE-989944
• Length: 764
• Species: Xenopus tropicalis
• Alignment Length: 709
• Identity: 195/709 - (27%)
• Similarity: 332/709 - (46%)
• Gaps: 85/709 - (11%)

  Fly    37 KELMRQAKAAEIESFMNQKVD----PCKDFYAFSCGNYKRINSALNMRVLTTGVFETLTKGLNRK 97
            |..||.:|      |:...:|    ||.|||:|:||.:.| ...:....|..|....:.:....|
 Frog    96 KAFMRASK------FITNNIDPTISPCTDFYSFACGGWLR-RHGIPEDKLIYGTIAAIGEQNEEK 153

  Fly    98 ILKMLNTP-HDSHDTPEDIQVKHFYESCLQIKELNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDF 161
            :..:|..| ...|....:.:||.|::|||.:::::...:..:.::|.:.|...|.|....|.|..
 Frog   154 LEHLLLQPVRRKHKGSAERKVKEFFKSCLNMRDIDRLGARPMLQVIEDCGGWDLPEDPRTQWDFN 218

  Fly   162 DWLNTTARMAHRYGIMSIIGVGVATDFANNQKNIIYINQQEFPLKTRSMYM--DNETAIYRQNYQ 224
            :.|..|..:   |.......:.|:.|..|:.:.||.|:|....|..|::|:  |.|:....:.|:
 Frog   219 ELLYKTQGV---YSTAVFFSMTVSLDDKNSSRYIIRIDQDGLTLPERTLYLGQDEESIKVLEAYK 280

  Fly   225 NNIQLILEKYLGVKDELARKAAKEMFEFEVDLAHGLVD--NNKHLNLRDLIELLTVAELRERYAP 287
            ..:|.|| ..|||  |..:|.|:|:...|..|::..:.  ::...::..:...:|:|:| ::..|
 Frog   281 VFMQTIL-SLLGV--ENVQKKAEEILHLEQHLSNITISEFDDMRRDISTMYNKVTLAQL-QQITP 341

  Fly   288 TLDTDQLIFVSMGEKISDKVYEYN-----------RRYQQNLVEVIERTPKSTVANYLFLRL--- 338
            .|:...|:         ::::..|           ..|.|.:.|:|..||.|.:.||:..|:
 Frog   342 HLNWKNLL---------NRIFHTNFPEDEEVVVLATDYMQKVSEMIRSTPASVLHNYMLWRIVVV 397

  Fly   339 ------------IWEFIQKPSGVAEKP---TEACVDFTKTYFAKNLDNMIYRRYKNEKSSREIDS 388
                        |.|..::..| :||.   |:.|:.....:|...|..:....|.:..|..::..
 Frog   398 LSEHLSTPFRDAIHELSKEMEG-SEKQAELTKVCLTQANKHFGMALGALFVEEYFSSSSKAKVQQ 461

  Fly   389 MWHQLKSTFKETLLSSPALDWIEPSTRSLAIAKLEAMTLEVNN----YVKENFTEEFA-DLNLQN 448
            :...:|......|   ..|||::..|:..|..||:.|.:.:..    ...|:..:|:. ::|.:.
 Frog   462 LVENIKHILDYRL---EELDWMDTETKQAAREKLKHMMVMIGYPDVLLQPESMDKEYEFEVNEKT 523

  Fly   449 --TDCVENLRQVQMLQAKQMRQLYHQPAKPLEAGELLSYTPSNILLENSIKVPVALLQPFYIWSD 511
              .:.:.::|....:..:::||...:.|..|....|.:|...|   :|.:..|..:||| .::..
 Frog   524 YFKNILNSIRYSIKMAVRRIRQEVDKSAWLLPPQALNAYYLPN---KNQMVFPAGILQP-TLYDP 584

  Fly   512 VYPNAVMFGTLAYLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYD 576
            .:|.::.:|.:..:|||||.||:||.|.::|..||...||.|.|.|.|||:.:|....|..:...
 Frog   585 DFPQSLNYGGIGTIIGHELTHGYDDWGGQYDANGNPIQWWTEDSYSKFLKKAECIVDLYENFTVY 649

  Fly   577 GIQLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFA 641
            ..::...|...|||||.||::|||.||:||..:     ||.:    ..||.|:||..|||||:||
 Frog   650 NQRVNGRTTLGENIADLGGLKLAYYAYQKWVRD-----NGPE----RPLPRLKYTHDQLFFIAFA 705

  Fly   642 QSWCNDVHPKVKALQVSTDDHMPGKFRVIGTLSNFEEFSKEFNCHAGSAMNPIEKCILY 700
            |:||.....:...|||.||.|.|..:||:|::|.||||.:.|:|...|.|||:.||.::
 Frog   706 QNWCIKRRSQSIYLQVLTDKHAPEHYRVMGSVSQFEEFGRVFHCPRNSPMNPVHKCSVW 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl20	NP_651645.1	M13	56..697	CDD:341056	188/685 (27%)
ecel1	XP_012818808.2	M13	113..762	CDD:341056	188/682 (28%)