Protein Alignment Nepl19 and Ece1

DIOPT Version :9

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: XP_006239337.1
• Gene: Ece1 / 94204
• RGDID: 620293
• Length: 769
• Species: Rattus norvegicus
• Alignment Length: 704
• Identity: 163/704 - (23%)
• Similarity: 283/704 - (40%)
• Gaps: 134/704 - (19%)

  Fly    59 LSKSAEMRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQ---QRLME 120
            :|.::.:.:.|....|.|::|:.|:||.|.:.||..|.:.|...|..|    :.|.|   :.|:|
  Rat   104 VSVTSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGHSRWGTFSNL----WEHNQAIIKHLLE 164

  Fly   121 QPANVETDEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEFDWL 185
            .  :..:...|..:.:.:|.:|:...:: |:|..:.|.|::...|...:..    .|..:.|.
  Rat   165 N--STASASEAEKKAQVYYRACMNETRI-EELRAKPLMELIEKLGGWNITG----PWAKDNFQ-- 220

  Fly   186 DTVARIKRQYGFDILLLFQQSADR-------IYVGQPKQILP-------EANRKAVAEDIANH-- 234
            ||:..:...|..........|||.       |.|.|....||       :...:.|.....|:
  Rat   221 DTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMV 285

  Fly   235 -LERHLG------VDPKVAVTTAREITEFEQKIAAIMV------DRRVGVMSKLYTPSDADYVDV 286
             |.:.||      :.|::     ::|.:||..:|.|.:      |..: :..|:...........
  Rat   286 QLGKLLGGGDEDSIRPQM-----QQILDFETALANITIPQEKRRDEEL-IYHKVTAAELQTLAPA 344

  Fly   287 SKLTQFVETVL-DRELLANESLYQHVPDYLMKIDELVTETPPHVLANYVFNELLK---HFYYERA 347
            .....|:..:. ..|:..:|.:..:..:||.::..|:..|...:|.||:...|::   .|..:|.
  Rat   345 INWLPFLNAIFYPVEINESEPIVVYDKEYLRQVSTLINSTDKCLLNNYMMWNLVRKTSSFLDQRF 409

  Fly   348 ESVVEQ------------------CVSRVRDLFGELLDHMLFEQ--YEDEGTLKDIYVVWQQLQR 392
            :...|:                  |||...:..|..|..|..:.  .||...:....::  ::::
  Rat   410 QDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIIL--EIKK 472

  Fly   393 SFRGVLQNSSANWLVPETREQLLEQLNTTSLVINGYAEVNFTQRYEELH-------LKPRDYLHN 450
            :|...|  |:..|:..:||....|:.:....:| ||.  ||....:||.       ..|..|..|
  Rat   473 AFEESL--STLKWMDEDTRRSAKEKADAIYNMI-GYP--NFIMDPKELDKVFNDYTAVPDLYFEN 532

  Fly   451 LRTILNHQSLRVKV--------KTQTSVT-------YDPVGKRVLLPVALLQPNFLWSRYYPKAV 500
            .....|. |.||..        :.|.|:|       |.|....::.|..:||..| ::|..|.|:
  Rat   533 AMRFFNF-SWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPF-YTRSSPNAL 595

  Fly   501 RYGSLGTLLAQQLAHSLEDASK-----------WDAKSFAEYSKRKSCFKEQYGRLRLNGHYLPE 554
            .:|.:|.::..:|.|:.:|..:           |...|...:.::..|..:||....:||..:..
  Rat   596 NFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQQYNNYSVNGEPVNG 660

  Fly   555 SDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSES-LPQLNLGSRRLFFLSFAQLWCNDANEQ 618
            .....||||||..::.||.||:..:.:     .|:|. ||.|.|.|.:||||.|||:||:
  Rat   661 RHTLGENIADNGGLKAAYRAYQNWVKK-----NGAEQILPTLGLTSNQLFFLGFAQVWCS----- 715

  Fly   619 FRDKQSLFLG------TPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
            .|..:|...|      :|:..||:|:|||.:.|...|.|...|.|....||:::
  Rat   716 VRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPLGSPMNPRHKCEVW 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	159/685 (23%)
		M13	73..664	CDD:189000	160/686 (23%)
Ece1	XP_006239337.1	PepO	105..769	CDD:226118	163/701 (23%)
		M13	118..767	CDD:189000	160/686 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344486
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.850