Protein Alignment Nepl19 and ece2b

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: XP_073779419.1
• Gene: ece2b / 793465
• ZFINID: ZDB-GENE-131120-140
• Length: 800
• Species: Danio rerio
• Alignment Length: 721
• Identity: 171/721 - (23%)
• Similarity: 289/721 - (40%)
• Gaps: 160/721 - (22%)

  Fly    69 MQQDADACENFYDYSCGNWPQINPANDAYPRETNF------VQLLLKAYSHKQQRLMEQPANVET 127
            :.:.||.|::||.|:||.|.:.||..|...|.:.|      .|.:||       .|:|. ....:
Zfish   117 LDRSADPCQDFYQYACGGWVRKNPLPDGRSRWSTFNSIWDQNQAVLK-------HLLEN-GTFNS 173

  Fly   128 DEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEFDWLDTVARIK 192
            ...|..:.:.:|.|||..::: |:|..:.|.:::...|...:.    :.|..|.|  ||.:..|.
Zfish   174 SSEAERKTQSYYLSCLNEQRI-EELGAQPLMDLITKIGGWNIT----ESWDKENF--LDVLKIIS 231

  Fly   193 RQYGFDILLLFQQSADR-------IYVGQPKQILP-------EANRKAVAE--DIANHLERHLGV 241
            ..|..........|.|.       |.|.|....||       :.|.|.:..  |....|...||.
Zfish   232 GPYRAQPFFTVSVSVDPKNSNSNVIQVDQSGLFLPSRDYYLNKTNEKVLKAYLDYMVELGLLLGG 296

  Fly   242 DPKVAVTTAREITEFEQKIAAIMV---DRRVGVMSKLY---TPSD-------ADYVDVSKLTQFV 293
            |........::|.:||..:|.|.|   :||  ...|:|   |.:|       .:::|      ::
Zfish   297 DKNSTRGQMQQILDFETALANITVPQDERR--DEEKIYHKITIADLQVLAPAIEWLD------YL 353

  Fly   294 ETVLD-RELLANESLYQHVPDYLMKIDELVTETPPHVLANYVF-------------------NEL 338
            .:||. .||...|.:..:..:|:.::.||:.:|...:|.||:.                   ::|
Zfish   354 NSVLSPLELNDTEPVVVYAKEYMQQVSELINKTDHSLLNNYMIWNLVQKGASSLDQRFENAQDKL 418

  Fly   339 LKHFYYERAESVV--EQCVSRVRDLFGELLDHML----FEQYEDE-----------------GTL 380
            |:..|..:.....  :.|:....|..|..|..:.    |::...|                 .|:
Zfish   419 LESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVKATFDKQSKEIDLNGGAFLPSCGRNVNSTV 483

  Fly   381 KDIY--VVWQ------QLQRSFRGVLQNSSANWLVPETREQLLEQ--------------LNTTSL 423
            .::.  |:.|      :::.:|:|.|.:  ..|:..:||:...::              |::..|
Zfish   484 HNLMFSVITQAEGMINEIRTAFKGALDD--LKWMDEQTRQAAKDKADAIYDMIGFPDFILDSKEL 546

  Fly   424 --VINGY--AEVNFTQRYEELH-LKPRDYLHNLRTILNHQSLRVKVKTQTSVTYDPVGKRVLLPV 483
              |.:||  .|.||.|.....: ...|.....||...|.....:...| .:..|.|....::.|.
Zfish   547 DDVYDGYEVTEDNFFQNMINFYNFSARVMADQLRKPPNRDQWSMTPPT-VNAYYMPTKNGIVFPA 610

  Fly   484 ALLQPNFLWSRYYPKAVRYGSLGTLLAQQLAHSLEDASK-----------WDAKSFAEYSKRKSC 537
            .:||..| :::.:|||:.:|.:|.::..:|.|:.:|..:           |...|...:..|..|
Zfish   611 GILQAPF-YAQDHPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRSWWQNSSVEAFKNRTEC 674

  Fly   538 FKEQYGRLRLNGHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSES-LPQLNLGSRR 601
            ..:||.:..:||.::.......||||||..::.||||||..:.:     .|.|. ||.:||.:.:
Zfish   675 MVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVQK-----NGEEKRLPAVNLTNDQ 734

  Fly   602 LFFLSFAQLWCNDANEQFRDKQSLFLG------TPNALRVLGALSNFRAFGRDFNCGTASRMTSP 660
            |||:.|||:||:     .|..:|...|      :|...||:|.|||...|...|.|...|.|.|.
Zfish   735 LFFVGFAQVWCS-----VRTPESAHEGLMTDPHSPPKYRVIGTLSNSPEFAEHFQCPLGSSMNSG 794

  Fly   661 QKCQLF 666
            .:|:::
Zfish   795 HRCEVW 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	170/713 (24%)
ece2b	XP_073779419.1	None