Protein Alignment Nepl19 and Ecel1

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: XP_063123735.1
• Gene: Ecel1 / 60417
• RGDID: 61806
• Length: 792
• Species: Rattus norvegicus
• Alignment Length: 727
• Identity: 161/727 - (22%)
• Similarity: 286/727 - (39%)
• Gaps: 171/727 - (23%)

  Fly     5 GIAHALLQLLLLHLVGSGR----GHLLTGQPAIDLRIQAREQLISQSNDSAYVQRLMRLSKSAEM 65
            |:...|..:|.|..:|.|.    |....|.|  :.:..||......:|..|.:
  Rat    71 GLCAILAAMLALKYLGPGAAGTGGACPEGCP--ERKAFARAARFLSANLDASI------------ 121

  Fly    66 RSYMQQDADACENFYDYSCGNWPQINPANDAYPRET---NFVQLLLKAYSHKQQRLMEQPANVET 127
                    |.|::||.::||.|.:    ..|.|.:.   ..:..:.:....:.:||:.:|.. ..
  Rat   122 --------DPCQDFYSFACGGWLR----RHAIPDDKLTYGTIAAIGEQNEERLRRLLARPTG-GP 173

  Fly   128 DEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPV---LSLPG-QEWPAEEFDWLDTV 188
            ...|..:::.|:.|||..|:: |.|..|.:.|::.|.|...:   ...|| ..|......:
  Rat   174 GGAAQRKVRAFFRSCLDMREI-ERLGPRPMLEVIEDCGGWDLGGAADRPGAARWDLNRLLY---- 233

  Fly   189 ARIKRQYGFDILLLFQQSA---DR------IYVGQPKQILP---------EANRKAVA--EDIAN 233
               |.|..:....||..:.   ||      |.:.|....||         |.:.|.:|  :....
  Rat   234 ---KAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEESEKVLAAYKVFME 295

  Fly   234 HLERHLGVDPKVAVTTAREITEFEQKIAAIMV----DRRVGVMSKLYTPSDADYVDVSKLTQ--- 291
            .|.|.||.|  .....|:||.:.||::|.|.|    |.|..| |.:|  :......:.|:|.
  Rat   296 RLLRLLGAD--AVEQKAQEILQLEQRLANISVSEYDDLRRDV-SSVY--NKVTLGQLQKITPHLQ 355

  Fly   292 ---FVETVLDRELLANESLYQHVPDYLMKIDELVTETPPHVLANYV---------------FNEL 338
               .::.:...:....|.:.....||:.::.:|:..||..:|.||:               |.|.
  Rat   356 WKWLLDQIFQEDFSEEEEVVLLATDYMQQVSQLIRSTPRRILHNYLVWRVVVVLSEHLSPPFREA 420

  Fly   339 LKHFYYE-----RAESVVEQCVSRVRDLFGELLDHMLFEQY-------EDEGTLKDI-YVVWQQL 390
            |.....|     :.:.:...|:.:....||..|..:...::       :.:..::|| |::.|:|
  Rat   421 LHELAKEMEGNDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRL 485

  Fly   391 QRSFRGVLQNSSANWLVPETREQLLEQLNTTSLVINGYAEV-----NFTQRYE-ELHLKP--RDY 447
            :          ..:|:..:|:.....:|. ..:|:.||.:.     ...:.|| |:|.|.  ::.
  Rat   486 E----------ELDWMDAQTKAAARAKLQ-YMMVMVGYPDFLLKPEAVDKEYEFEVHEKTYFKNI 539

  Fly   448 LHNLR--TILNHQSLRVKVKTQT--------SVTYDPVGKRVLLPVALLQPNFLWSRYYPKAVRY 502
            |:::|  ..|:.:.:|.:|...|        :..|.|...:::.|..:|||. |:...:|:::.|
  Rat   540 LNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPT-LYDPDFPQSLNY 603

  Fly   503 GSLGTLLAQQLAHSLED-----------ASKWDAKSFAEYSKRKSCFKEQYGRL-----RLNG-H 550
            |.:||::..:|.|..:|           ...|...|::.:..:..|....|...     |:|| |
  Rat   604 GGIGTIIGHELTHGYDDWGGQYDRSGNLLHWWTEASYSRFLHKAECIVRLYDNFTVYNQRVNGKH 668

  Fly   551 YLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQLNLGSRRLFFLSFAQLWCNDA 615
            .|      .|||||...:::||:||::.:.|..|    ...|.:|.....:|||::|||.||..
  Rat   669 TL------GENIADMGGLKLAYYAYQKWVREHGP----EHPLHRLKYTHNQLFFIAFAQNWCIK- 722

  Fly   616 NEQFRDKQSLFL 627
                |..||::|
  Rat   723 ----RRSQSIYL 730

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	148/655 (23%)
Ecel1	XP_063123735.1	None