Protein Alignment Nepl19 and Nepl20

DIOPT Version :9

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Alignment Length: 713
• Identity: 221/713 - (30%)
• Similarity: 369/713 - (51%)
• Gaps: 96/713 - (13%)

  Fly    25 HLLTGQPAIDLRIQAREQLISQSNDSAYVQRLMRLSKSAEMRSYMQQDADACENFYDYSCGNWPQ 89
            |:|:   .:.|.....|.:::|  |:.|::.|||.:|:||:.|:|.|..|.|::||.:||||:.:
  Fly    13 HVLS---VLVLAAPTSEDVLNQ--DTPYMKELMRQAKAAEIESFMNQKVDPCKDFYAFSCGNYKR 72

  Fly    90 INPANDAYPRETNFVQLLLKAYSHKQQRLMEQPANVETDEVAVLRLKEFYASCLLFRQVPEDLYR 154
            ||.|.:.....|...:.|.|..:.|..:::..|.: ..|....:::|.||.|||..::: ...|.
  Fly    73 INSALNMRVLTTGVFETLTKGLNRKILKMLNTPHD-SHDTPEDIQVKHFYESCLQIKEL-NSTYS 135

  Fly   155 RQLQEIVADFGRMPVLSLPGQEWPAEEFDWLDTVARIKRQYGFDILL-------LFQQSADRIYV 212
            .:|:.::|:||.||:|.  |..|..::||||:|.||:..:||...::       ......:.||:
  Fly   136 EKLKRLIAEFGTMPLLE--GSSWQEDDFDWLNTTARMAHRYGIMSIIGVGVATDFANNQKNIIYI 198

  Fly   213 GQPKQILPEAN----------RKAVAEDIANHLERHLGVDPKVAVTTAREITEFEQKIAAIMVDR 267
            .|.:..|...:          |:....:|...||::|||..::|...|:|:.|||..:|..:||.
  Fly   199 NQQEFPLKTRSMYMDNETAIYRQNYQNNIQLILEKYLGVKDELARKAAKEMFEFEVDLAHGLVDN 263

  Fly   268 R-------------VGVMSKLYTPSDADYVDVSKLTQFV---ETVLDRELLANESLYQHVPDYLM 316
            .             |..:.:.|.|:    :|..:|. ||   |.:.|:       :|::...|..
  Fly   264 NKHLNLRDLIELLTVAELRERYAPT----LDTDQLI-FVSMGEKISDK-------VYEYNRRYQQ 316

  Fly   317 KIDELVTETPPHVLANYVFNELLKHFYYER---AESVVEQCVSRVRDLFGELLDHMLFEQYEDEG 378
            .:.|::..||...:|||:|..|:..|..:.   ||...|.||...:..|.:.||:|::.:|::|.
  Fly   317 NLVEVIERTPKSTVANYLFLRLIWEFIQKPSGVAEKPTEACVDFTKTYFAKNLDNMIYRRYKNEK 381

  Fly   379 TLKDIYVVWQQLQRSFRGVLQNSSA-NWLVPETREQLLEQLNTTSLVINGYAEVNFTQRYEELHL 442
            :.::|..:|.||:.:|:..|.:|.| :|:.|.||...:.:|...:|.:|.|.:.|||:.:.:|:|
  Fly   382 SSREIDSMWHQLKSTFKETLLSSPALDWIEPSTRSLAIAKLEAMTLEVNNYVKENFTEEFADLNL 446

  Fly   443 KPRDYLHNLRTI----------LNHQSLRVKVKTQTSVTYDP----VGKRVLLPVALLQPNFLWS 493
            :..|.:.|||.:          |.||..: .::....::|.|    :...:.:|||||||.::||
  Fly   447 QNTDCVENLRQVQMLQAKQMRQLYHQPAK-PLEAGELLSYTPSNILLENSIKVPVALLQPFYIWS 510

  Fly   494 RYYPKAVRYGSLGTLLAQQLAHSLEDASK-----------WDAKSFAEYSKRKSCFKEQYGRLRL 547
            ..||.||.:|:|..|:..:|.|..:|:.:           ||.||.:.:.||:.||.:||||...
  Fly   511 DVYPNAVMFGTLAYLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVY 575

  Fly   548 NGHYLPESDLQAENIADNLAIQVAYHAYRR-----LLAELDPSFLGSESLPQLNLGSRRLFFLSF 607
            :|..|.||..|:||||||..:::||.|||:     |........:..|:||.|...:::|||:||
  Fly   576 DGIQLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISF 640

  Fly   608 AQLWCNDANEQFRDKQSLFLGT----PNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
            ||.||||.:.:.:   :|.:.|    |...||:|.||||..|.::|||...|.|...:||.|:
  Fly   641 AQSWCNDVHPKVK---ALQVSTDDHMPGKFRVIGTLSNFEEFSKEFNCHAGSAMNPIEKCILY 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	204/660 (31%)
		M13	73..664	CDD:189000	203/661 (31%)
Nepl20	NP_651645.1	PepO	50..691	CDD:226118	204/660 (31%)
		M13	56..697	CDD:189000	202/660 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451242
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	1	1.000	-	-		FOG0007609
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850