Protein Alignment Nepl19 and Nepl18

DIOPT Version :9

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Alignment Length: 666
• Identity: 198/666 - (29%)
• Similarity: 340/666 - (51%)
• Gaps: 67/666 - (10%)

  Fly    50 SAYVQRLMRLSKSAEMRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHK 114
            |.|.::::..:|.|||::.|:.:...|::||.::||||.:.|||.......|:..:|:.|.:..:
  Fly    35 SDYAKKIIVQAKVAEMKTMMKPEVSPCDDFYTHACGNWHRHNPAQLLGDVMTDNFKLISKGFDRR 99

  Fly   115 QQRLMEQPANVETDEVAVLRLKEFYASCLLFRQVPEDL-YRRQLQEIVADFGRMPVLSLPGQEWP 178
            .|||:.  ||....|:. .:::.||.||.|..:  :|: |:..|:.::.::|.:|  :|.|.:|.
  Fly   100 LQRLLR--ANDLQSELE-KKMQRFYMSCNLVHR--DDVHYKLALENVIREYGTLP--ALVGAQWN 157

  Fly   179 AEEFDWLDTVARIKRQYGFDILL-------LFQQSADRIYVGQPKQILPEANRKAVAEDI--ANH 234
            :.:|.|..|||:|:.:||..|::       :...|.:|:|:.||...........:.|::  :..
  Fly   158 SSDFSWWRTVAQIQHKYGKQIIIGLEIMHDIRNTSVNRVYISQPDFKTINTRLTNLMEEVRTSMD 222

  Fly   235 LERHLGVDPKVAVTTAREITEFEQKI------AAIMVDRRVGVMSKLYTPSDAD--YVDVSKLTQ 291
            |:::.|:...||..||.::||.|:..      ||.:.:     ...|||.:|..  |.|....|:
  Fly   223 LQQYFGLSSSVAKHTAEQLTELERTFSSGGSGAATLQE-----SLSLYTVADLQEKYSDHLNFTE 282

  Fly   292 FVETVLDRELLANESLYQHVPDYLMKIDELVTETPPHVLANYVFNELLKHFYYE-RAESVVEQCV 355
            |:..:|..|.:. :|||.:..:||.|....:..||....||||..:||:.|..: :.:.:|:.|.
  Fly   283 FLGLILGEENIP-KSLYIYDEEYLDKALLTMRSTPLATQANYVLWKLLEDFLVDAQPKDMVKWCT 346

  Fly   356 SRVRDLFGELLDHMLFEQYEDEGTLKDIYVVWQQLQRSFRGVLQNSSANWLVPETREQLLEQLNT 420
            ...:..||:|.:|.::::|.:.....:::.:|.|::..||..|.....:|:...||...:|:|..
  Fly   347 ESTKKYFGKLAEHAVYKRYRNPDVESEVHKIWDQIKGIFRQRLLGDKLDWISNATRTLAIEKLER 411

  Fly   421 TSLVINGYAEVNFTQRYEELHLKPRDYLHNLRTILNHQSLRVKVKTQT-------------SVTY 472
            ..|.||.|.|.||...|.|:.:...:|:.|::.:|..:.:|...:...             :..|
  Fly   412 MHLNINSYDEENFENVYGEVFIDRLNYVSNVQQLLIAKGIRFVARINQPADSVDATELLGFTPAY 476

  Fly   473 DPVGKRVLLPVALLQPNFLWSRYYPKAVRYGSLGTLLAQQLAHSLED-----------ASKWDAK 526
            :.....:.:|||||||.:.|...||:|::|.:||.|||.::.|..:|           |..||.|
  Fly   477 NIQENNITIPVALLQPRYFWGDQYPEALKYATLGYLLAHEMLHGFDDDGRQYDASGNLAPWWDLK 541

  Fly   527 SFAEYSKRKSCFKEQYGRLRLNGHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSES 591
            |..|:.:|:.||:.||...:..|..||||..|:|||||:..:::||.||...|.:.....|..|:
  Fly   542 SRYEFEERRKCFQAQYHEYQYGGSKLPESKDQSENIADSGGLKLAYAAYELWLGQQSEEVLQRET 606

  Fly   592 LPQLNLGSRRLFFLSFAQLWCNDANEQFR------DKQSLFLGTPNALRVLGALSNFRAFGRDFN 650
            :..|...||:||||.:|||.|:|....|:      |:.:     |:..||:|.||||:.|...||
  Fly   607 MEGLPFNSRQLFFLGYAQLLCDDVQFLFQPWVSQSDRHA-----PSKYRVIGPLSNFQEFPWVFN 666

  Fly   651 CGTASRMTSPQKCQLF 666
            |..::.|....||.::
  Fly   667 CSQSAPMDPEYKCAIY 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	189/638 (30%)
		M13	73..664	CDD:189000	190/639 (30%)
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	192/645 (30%)
		M13	58..679	CDD:189000	189/638 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451246
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	1	1.000	-	-		FOG0007609
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850