Protein Alignment Nepl19 and Nepl16

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Alignment Length: 677
• Identity: 140/677 - (20%)
• Similarity: 245/677 - (36%)
• Gaps: 162/677 - (23%)

  Fly    62 SAEMRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQQRLMEQPANVE 126
            ::.:::.:..:.|.|..|..:||  |     .|......||.:::.....|...|.|......:.
  Fly   164 ASSIQARLNWNKDPCTEFKKFSC--W-----RNTPNKNITNLIEMGNSQKSVDSQMLYLFQNKIM 221

  Fly   127 TDEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSL-PGQEWPAEEFDWLDTVAR 190
            .....:|.  ..:.|||  :|........::.:.:.  |.:||.|: |....|        .:|:
  Fly   222 NGSFGILH--NLFESCL--QQTTNSTVMHRIFDSLG--GYLPVGSVGPSSIAP--------LIAK 272

  Fly   191 IKRQYGFDILLLFQQSADRIYVGQPKQIL------------------------PEANRKAVAEDI 231
            |   |......|.....|..|..:|..:|                        |...|:.|.:.:
  Fly   273 I---YDLGPSPLVDLYHDLSYGRRPHILLIISGPSTSSTILERKIRWMSPKAPPSRIRQGVPKLL 334

  Fly   232 ANHLERHLG--VDPKVAVTTAREITEFEQKIAAIMVDR-RVGVMSK--LYTPSDADYVDVSKLTQ 291
            |:.:|..|.  |.....|:....|.||.:.:..:.|:. |.|....  ||        :||.| |
  Fly   335 ADLIENFLPYFVSYAQRVSEKDTIFEFIKDLNKLQVEHSRRGFWDSTVLY--------NVSSL-Q 390

  Fly   292 FVETVLDRELLANES----LYQHVPDYLMKIDELVTETPPHVLANYVF----NELLKHFYYERAE 348
            .:..||:..||..::    :.....|||..::..:|:.|..|..|.:.    .::|...|
  Fly   391 DLYPVLNWTLLIPQNWSGPIVVRNSDYLKALEYFLTKYPTRVAHNSLLLLSALQILPRDY----- 450

  Fly   349 SVVEQCVSRVRDLFGELLDHMLFEQYEDE---GTLKDIYVVWQQLQR------SFRG-------V 397
            ...|.|.........||...:...|:..|   .|.|...::::.|:.      |.:|       .
  Fly   451 PSPEVCTRSTMWALPELSSSLYIAQHSSEDLKDTTKRAEIIFKSLKAHLKRAPSLKGAALVKLSA 515

  Fly   398 LQNSSANWLVPETREQLLEQLNTTSLVINGYAEVNFTQRYEELHLKPRDYLHNLRTILNHQSLRV 462
            |:..|..|........||:.|...::....:.: |..:.|::..|:|.|...|..   :|.:...
  Fly   516 LKIQSQTWEGFSNTTDLLKSLQPLNITSECWFQ-NILEIYKKNKLEPNDISLNGG---SHDAWAY 576

  Fly   463 KVKTQTSVTYDPVGKRVLLPVA-LLQPNFLWSRYYPKAVRYGSLGTLLAQQLAHSLEDASKWDAK 526
            .:  .:::.||.:...:::|:: :|.|.|  :...|..:.|.|:|..:|:::..|:       .|
  Fly   577 PI--VSTIFYDTLSHSIVVPLSVILIPYF--NAVLPPYLHYASVGVSIAKEILRSI-------TK 630

  Fly   527 SFAEYSKRKSCFKEQYGRLRLNGHYLPESDLQAENIADNLA----------IQVAYHAYRRLLAE 581
            ||.|.:.|  |              :|.|    .||..|.:          :|::||:    :..
  Fly   631 SFDEKAMR--C--------------VPHS----VNIFSNYSRMDILIHSGGMQISYHS----MLS 671

  Fly   582 LDPSFLGSESLPQLNLGSRRLFFLSFAQLWCNDANEQFRDKQSLFLG----TPNALRVLGALSNF 642
            |.....|...||.|||...::|||..||..|.::|         :||    .|....:||.|.
  Fly   672 LTGPIKGMARLPGLNLTPTQIFFLVSAQELCAESN---------YLGIDTNAPEFDNILGWLV-- 725

  Fly   643 RAFGRD----FNCGTASRMTSPQKCQL 665
             |.|..    |.|.:.|.:...:.|.:
  Fly   726 -AQGGSATEVFKCPSGSMINVQKTCNV 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	139/663 (21%)
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	139/662 (21%)