Protein Alignment Nepl19 and Nepl9

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 735
• Identity: 145/735 - (19%)
• Similarity: 226/735 - (30%)
• Gaps: 251/735 - (34%)

  Fly    41 EQLISQSNDSAYVQRLMRLSKSAEMRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFVQ 105
            :||:...|||                      .|.|::||.::|||:.|        .:|.|...
  Fly    51 QQLVKIKNDS----------------------MDPCDDFYAHACGNFDQ--------TKEENSDD 85

  Fly   106 LLLKAYSHKQQRLMEQPANVETDEVAVLRL-KEFYASCLLFRQ----VPEDL---YRRQLQEIVA 162
            .|.....:||.|:....|.|...|....|| .:.|..|....:    .|..|   :.|.|.||..
  Fly    86 FLPPYLYNKQDRMNFFTAEVGNFETIPGRLISQLYTECRKREERNVFTPTRLTSHWERMLDEIPF 150

  Fly   163 DFGRMPVLSLPGQEWP-----------AEEFDWLDTVARIKRQYGFDILLLFQQSADRIYVGQPK 216
            ......|||    .||           ..:.:|:...|:: ..:|...||....:.|.||| .|.
  Fly   151 LARHKEVLS----SWPFLKHQWERRRLYGQLNWIVLSAQL-AAHGLPTLLHIYFALDTIYV-SPM 209

  Fly   217 QILPEANRKAVAEDIANHLERHLGVDPKVAVTTAREITEFEQKIAAIMVDRRVGV-------MSK 274
            :.||                             ...|.:|:..::.::..|...|       |..
  Fly   210 EELP-----------------------------CPSIADFQSSLSDVLEGRHHQVSRIISHEMRV 245

  Fly   275 LYTPSDADYVDVSKLTQFVETVLDR----ELLANESLYQHVPDYLMKID---------------- 319
            |......:...|..|:|...|...|    :||.:|:...:...|...::
  Fly   246 LCREMRGELPLVRSLSQNTRTNTSRPGEEQLLLDENTMDYFQQYFAALNFSEERLVGARKFPLDV 310

  Fly   320 -------ELVTETPPHVLANYVFNELLKHFYYERAESVVEQCVSRVRDLFGELLD------HMLF 371
                   |::..|...::.|||..:..:...|       ..|. ||.:.|..||.      |:|.
  Fly   311 EKITQAWEVLRHTETRIVYNYVMWQAREQLRY-------PDCY-RVSEEFERLLHAEYWQWHVLR 367

  Fly   372 EQYEDEGTLKDIYVVWQQLQRSFRGVLQNSSANW---LVPETREQLLEQLNTTSLVINGYAE--V 431
            .....|..|....:...:.|:..|..|  |..:|   |.|.:.|:  ::|....::.| :||  :
  Fly   368 RHLSREVALASYQLHTTRFQKLRRSKL--SRRDWYGHLWPASVEK--KELQVARILQN-HAENYL 427

  Fly   432 NFT---QRYEELHLKPRDYLHNL----RTILNHQSLRVKVKTQTSVTYDPVGKRVLLPVALL--- 486
            |.|   :.||.|.|:...:..||    |..|.|..:...| .:..|.......|..|...||
  Fly   428 NITELNENYEGLKLEKNSFYANLLILRRAQLRHSFVSPYV-DEEDVNQPAYFLRHFLHFVLLSLH 491

  Fly   487 QPNFLWSRYYPKAVRYGSLGTLLAQQLAHSLEDASKWDAKSFAEYSKRKSCFKEQYGRLRLNGHY 551
            :|.:   .||                ..|.||                  .::|....|..:|||
  Fly   492 RPTY---HYY----------------ATHGLE------------------LWRESRLLLDTDGHY 519

  Fly   552 LPESDLQAENIADNLAIQVAYHAYRRLLAELDPSF--LGSESLPQL------------------- 595
            .....|:.:             :::...|:|.|.:  |||..:.::
  Fly   520 TAMDCLERQ-------------SFQHYDAKLAPIYRPLGSHEIAEIFQFYRSFQYSLTDYHFWLQ 571

  Fly   596 ---------------NLGSRRLFFLSFAQLWCNDANEQFRDKQSLFLGTPNALRVLGALSNFRAF 645
                           .|...|:.|.:.||..||...|.|            |.::.....|...|
  Fly   572 GERFAFAETFVLDYFGLNPHRVLFYAVAQQLCNRQTEIF------------AAQLNRGYMNLPEF 624

  Fly   646 GRDFNCGTASRMTSPQKCQL 665
            ...|.||....|..|.:|.:
  Fly   625 QEAFKCGAEKAMNPPSRCMI 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	139/700 (20%)
Nepl9	NP_609815.1	GluZincin	62..642	CDD:472708	139/698 (20%)