Protein Alignment Nepl19 and Nepl8

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Alignment Length: 693
• Identity: 143/693 - (20%)
• Similarity: 267/693 - (38%)
• Gaps: 154/693 - (22%)

  Fly    43 LISQSNDSAYVQRLMRLSKSAEMRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFVQLL 107
            |::.|:::..:..::         |::.::|:.|||:|:::||.: .:...:|.:   .:.:|:|
  Fly    11 LVAASSNTRLLNGIL---------SHVDKEANPCENYYNHACGQY-NMRHIDDTF---FDIIQML 62

  Fly   108 LKAYSHKQQRLMEQ--------PANVETDEVAVLRLKEFYASCLLFRQVPE--DLYRRQLQEIVA 162
            ....:....:||::        ..||.:.:..|||   :|.||   |..|.  |...:.|:.|..
  Fly    63 DHQVNQNLVKLMDELEMSSQLPDFNVSSVDGKVLR---YYLSC---RGAPRNMDSLSQYLKVISP 121

  Fly   163 DFG-RMPVLSLPGQEWPAEEFDWLDTVARIKRQYGFDILLLFQQSADRIYVGQPK---QILPEAN 223
            ..| ..|.....|..||.|.|.||..:|.:.| ||...:....:     .|..|:   :.:.|.|
  Fly   122 GEGLTWPQFIPDGSSWPQENFKWLKALAHLHR-YGLTNVFFNLE-----VVSNPRNASEYMVELN 180

  Fly   224 RKAVAED--IANHLERHLGVDPKVAVTTAREITEFEQKIAAIMVDRRVGVMSKLYTPSDA---DY 283
            .....|:  :.|.....|.|...:.|.:: ||....:|:..:.:     ::..:..|.|.   .|
  Fly   181 TPTFGEESQLPNSFIEILSVLYIIKVPSS-EIITLARKMRTLEL-----LLKTMINPIDTLNNRY 239

  Fly   284 VDVSKL--------TQFVETVLDRELLANESLYQHVPDYLMKIDELVTETPPHVLANYVFNELLK 340
            :.:...        .:|.|.::.........:......|...:.||:.:....::|:|:......
  Fly   240 ISIRDFQMETGHNWQRFFEILIGSSAAPELQVLVRNFRYFTALKELMDKQDARLVASYIMTRFAI 304

  Fly   341 HFYYER---AESVVEQCVSRVRDLFGELLDHMLF-EQYEDEGT-------LKDIYVVWQQLQRSF 394
            ....|.   .||.  :|||:||... .|..:||: |::.::.|       :|||:   ::|:..|
  Fly   305 FLLDETMGGREST--ECVSQVRRNM-NLAANMLYKERFFEDSTFSANILEIKDIF---EKLRHQF 363

  Fly   395 RGVLQNSSANWLVPETREQLLE-------------QLNTTSL---------VINGYAEVNFTQ-- 435
              :||       |.:...:|..             ::|..:|         :...|.::.|..
  Fly   364 --LLQ-------VDQNHLELTALQMKFFVRKAEAIEINVVNLPKTDDLRHFIGQYYQDLQFPTGE 419

  Fly   436 -RYEELHLKPRDYLHNLRT-ILNHQSLRVKVKTQTSVTYDPVGKRVLLPVALLQPNF-LWSRYYP 497
             .|.:.|||...:    || .:..||.:...:.|..:||    :....|:...||.| |.|.
  Fly   420 LDYHQEHLKVLQF----RTQKMLAQSSKGHSEEQNILTY----RSQAAPLPPPQPFFQLESE--- 473

  Fly   498 KAVRYGSLGTLLAQQLAHSLEDASKWDAKSFAEYSKRKSCFKEQYGRLRLNGHYLPESDLQAENI 562
            ...:|..:|.::|..|..:.............:.|.|...|:|....|..|...:.||      :
  Fly   474 DVFKYSLMGYIMAHHLISAFATEGITIGSDGNDQSFRSHRFEEAVSCLSRNSENIDES------M 532

  Fly   563 ADNLAIQVAYHAYRRLLA---ELDPSFLGSESLPQLNLGSRRLFFLSFAQLWC--NDANEQFRDK 622
            .|...:::||..|.::..   .||.:.|..|          ::|||:..|.:|  :|...|:::.
  Fly   533 GDIAGLELAYFTYAKMAKNRNRLDFTHLPPE----------QIFFLNVGQFFCGNSDMLVQYKED 587

  Fly   623 QSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQL 665
            |         :|:..|:..|..|.:.|.|  .......:||:|
  Fly   588 Q---------VRLQRAIEGFEPFDKAFGC--YRNKPKHEKCRL 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	138/660 (21%)
Nepl8	NP_609795.2	GluZincin	32..618	CDD:472708	138/660 (21%)