Protein Alignment Nepl19 and Nepl5

DIOPT Version :9

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 701
• Identity: 163/701 - (23%)
• Similarity: 306/701 - (43%)
• Gaps: 121/701 - (17%)

  Fly    46 QSNDSAYVQRLMRLSKSAEMRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFV------ 104
            |:|....||.::    :.:::|||...|..|||||.|:|||| ||........|:.::.
  Fly    25 QTNAPQSVQEML----AEQLQSYMDTKARPCENFYQYACGNW-QIQQQEQHSLRDRDWTRDRQRY 84

  Fly   105 --QLL----LKAYSHKQQRLME------QPANVETDEVAVLRLKEFYASCLLFRQVPEDLYRRQL 157
              |:|    |....|...|.:|      ..::.|:|...:.:::.:|.||.  |..|.:| ::.|
  Fly    85 QGQMLPTDTLGLIDHSVNRKLELLLRRRNESSFESDSSILEQMRLYYRSCK--RLKPYNL-KKYL 146

  Fly   158 QEI-VADFGRMPVLSLPGQEWPAEEFDWLDTVARIKRQYGFDILLLFQQSADR--------IYVG 213
            |.: .::..:.|.:   |:.|..|.|||:.|:.|: |.:|.:.:||.::...|        |||.
  Fly   147 QLLPPSNSTQWPSV---GRGWRPERFDWITTLGRL-RLHGLNGVLLREEVLPRWDDSRNYSIYVN 207

  Fly   214 QPKQILPEANRKAVAEDIANHLERHLGVDPKVAVTTAREITEFEQKIAAIMV---DRRVGVMSKL 275
            :|.:    ...:.:.|.....|...:|...:.|...||::.:||:|:..:..   |.....|...
  Fly   208 KPSR----QETQPMGEGAMIELLLDIGQTKRTANALARQVDDFERKLHRLQELEDDEGPREMQLG 268

  Fly   276 YTPSDADYVDVSKLTQFVETV-LDREL-LANESLYQHVPDYLMKIDELVTETPPHVLANYVFNEL 338
            |..|   |:...:...|:..| :|.|| |.:..:.:::| ||..:.:|:....|..:.:|:   :
  Fly   269 YLDS---YLPQLRWLSFMRQVRIDSELDLRSTLIIENIP-YLRALSDLMESESPDTVCSYI---M 326

  Fly   339 LKHFYYERAESVVE----QCVSRVRDLFGELLDHMLFEQYEDEGTLKDIYVVWQQLQRSFRGVLQ 399
            ||...:.:.:...:    :||:.:|.........::.:|:.|..:...:..::|:|:..|..:|.
  Fly   327 LKWLAFLKQQGPADISRGECVAALRRAMPLASSWLVGQQFSDPESESYVSSLFQRLKVRFGQILA 391

  Fly   400 NSSANWLVPETREQLLEQLNTTSLVINGYAEVNFTQRYEELH----LKPRDYLHNLRTIL----- 455
            .:... |.|.....|.::|....|.: |:.:....:..|:.|    |....:..|...:|
  Fly   392 ENRMR-LSPPLVHILQQKLRAVRLQM-GFFQTEEIEDVEQYHVRIDLSGHSFYGNQLVLLRQRVE 454

  Fly   456 -NHQSLRVKV-----KTQTSVTY----------DPVGKR----VLLPVALLQ-PNFLWSRYYPKA 499
             ||..|.:.|     .|.::::|          .|:..|    ||:|..||| |  :|.|.....
  Fly   455 ANHDLLYINVTNFANSTGSNLSYLSESWEASNSSPLYVRPRNLVLVPHGLLQLP--IWHRNISAL 517

  Fly   500 VRYGSLGTLLAQQLAHSLED-ASKWDAK-----------SFAEYSKRKSCFKEQYGRLRLNGHYL 552
            .::..:|.:||.:|||..:. ...:||.           :..::.:...|.::|   :.....::
  Fly   518 QQHAVMGFVLAHELAHGFDMLGMDYDAMGNIMGPVEEIGASRQFRQGLQCLQQQ---MATGSKWI 579

  Fly   553 PESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQLNLGSRRLFFLSFAQLWCNDANE 617
            .      |.:||.:|:::||..:..:..:.:|.   ...|||.:  .|:|||::|||.:|.....
  Fly   580 D------EKLADFVALRLAYETFFGVRDKREPR---DPLLPQFS--QRQLFFITFAQFFCGRTPV 633

  Fly   618 QFRDKQS--LFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
            .....||  ......:.|||:..|:||..|.|:|.|...::|.:.|:|:::
  Fly   634 LSPRSQSEAHLKHAADELRVMQTLANFEEFSREFGCDKKAKMQASQRCRIW 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	156/669 (23%)
		M13	73..664	CDD:189000	155/670 (23%)
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	159/678 (23%)
		GluZincin	48..682	CDD:301352	155/670 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454896
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850