Protein Alignment Nepl19 and Nep3

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Alignment Length: 774
• Identity: 182/774 - (23%)
• Similarity: 321/774 - (41%)
• Gaps: 157/774 - (20%)

  Fly     4 FGIAHALLQLLLLHLVGSGRG----HLLTGQPAIDLRIQAREQLISQSNDSAYVQRLMRLSK--- 61
            |.:|..:..||::.....|..    |:|..||              ...|......|..|:|
  Fly    59 FVMAITIFTLLIVLFTDGGSSDATKHVLHVQP--------------HQKDCPSGNELPCLNKHCI 109

  Fly    62 --SAEMRSYMQQDADACENFYDYSCGNWPQINPAND------AYPRETNFVQLLLKAYSHKQQRL 118
              |:|:...:....|.|::||.|||..|.:.||..:      .:.:.....||:::       .:
  Fly   110 FASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIR-------NV 167

  Fly   119 MEQPA-NVETDEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEF 182
            :|:|| :.::|  |..:.|.:|.|||...:..|.|..:.:.:::...|...|..   ..:....:
  Fly   168 LEKPAKSFKSD--AERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTK---SGYNVANW 227

  Fly   183 DWLDTVARIKRQYGFDILLLF-------QQSADRIYVGQPKQILPEA--------NRKAVAEDIA 232
            ....|:..:..:|.|:.|..:       ..|...|.:.|....||.|        |.:.|..:..
  Fly   228 TMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYI 292

  Fly   233 NHLER---HLGVDPKVAVTTAREITEFEQKIAAIMV---DRRVGVMSKLYTPSDADYVDVSKLTQ 291
            .::.:   .||.:...|......:..||:|:|.|.:   |||  ....:|.|....  .:|||..
  Fly   293 EYMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRR--NEEAMYHPMQLR--QLSKLAP 353

  Fly   292 FVE---------TVLDRELLANESLYQHVPDYLMKIDELV-----TETPPHVLANYV-------- 334
            |:.         .::.|.:..:|.:..:.||:|..:.:::     ||.....|.||:
  Fly   354 FLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTL 418

  Fly   335 -------FNELLKH-----FYYERAESVVEQCVSRVRDLFGELLDHMLFEQY---EDEGTLKDIY 384
                   |.:..|.     ...:..|.:...|||...::.|..:..:...|.   |.:...:.:.
  Fly   419 TSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMI 483

  Fly   385 VVWQQLQRSFRGVLQNSSANWLVPETREQLLEQLNTTSLVINGYAE-----VNFTQRYEELHLKP 444
            .   :::.:|:..|||  ..|:..:|||:.:|:.|..|.:| |:.:     |...::|.||::.|
  Fly   484 A---EIREAFKMNLQN--LTWVDKQTREKAIEKANQISDMI-GFPDYILDPVELDKKYAELNITP 542

  Fly   445 RDY--------LHNLRTILNHQSLRVKVKTQTSVT-------YDPVGKRVLLPVALLQPNFLWSR 494
            ..|        ::||::.|......|. ||...:|       |.|...:::.|..:||..| :..
  Fly   543 NAYFENNIQVAIYNLKSNLKRLDQPVN-KTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPF-FDI 605

  Fly   495 YYPKAVRYGSLGTLLAQQLAHSLEDASK-----------WDAKSFAEYSKRKSCFKEQYGRLRLN 548
            ..||::.:|::|.::..:|.|:.:|..:           ||:||...::::..|...||...::|
  Fly   606 NNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMN 670

  Fly   549 GHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQLNLGSRRLFFLSFAQLWCN 613
            |..|.......||||||..::.|||||:|..::.|...|   .||.|||...:|||:||||:||:
  Fly   671 GRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDIL---KLPGLNLTHSQLFFVSFAQVWCS 732

  Fly   614 DANEQF------RDKQSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
            ...::.      :|..|     |:..||:|.|||.:.|...|.|....||...:||:::
  Fly   733 STTDETNLLQMEKDPHS-----PSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	166/692 (24%)
Nep3	NP_523417.2	M13	123..784	CDD:341056	166/692 (24%)