Protein Alignment Nepl19 and Nep6

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_572831.2
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 718
• Identity: 162/718 - (22%)
• Similarity: 272/718 - (37%)
• Gaps: 188/718 - (26%)

  Fly    56 LMRLSKSAEMRSYMQQDADA----CENFYDYSCGNW-----PQINPANDAYPRETNFVQLLLKAY 111
            |::|:.:.:.:..:..|.||    ||||:.|:||||     .:|..|:|...:....::|.|..|
  Fly    19 LLKLAAAQDCQQQLDNDTDAEVKPCENFHQYACGNWYSNTSQRILGAHDMRSKWVANLKLQLIRY 83

  Fly   112 SHKQQRLMEQPANVETDEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQE 176
            ..:........||... ..:..:|...|..|||..|... .|...|....|:|   |:|:    .
  Fly    84 LEESSSTDSFSANTSV-TTSTAQLGTLYRCCLLSGQSIR-TYTDALSRSGANF---PLLA----N 139

  Fly   177 WPAEEFDWLDTVARIKRQYGFDIL--LLFQ---QSADR--IYVGQPKQIL----PEANRKAVAED 230
            .....|||:...|.: |.||...|  ||.:   ||||:  .|:..||..|    .|.| :.:.:.
  Fly   140 HTGGSFDWVLANAAL-RTYGAQGLWRLLVKDNWQSADQRIFYMLPPKFDLLGRDDELN-EFLYQR 202

  Fly   231 IANHLERHLGVDPKVAVTTAREITEFEQKIAAIMVDRRVGVMSKLYTPSDADYVDVSK------- 288
            ....|...||:..:.|...|.::..||:.:..::             |:||:...|.:
  Fly   203 YLKILLLELGLRVRRAALLAEKLVAFEKSLQKLL-------------PNDAEQTLVLRKPQSLKD 254

  Fly   289 ---------LTQFVETVLD------RELLANESLYQHVPDYLMKIDELVTE--TPPHVLANYVFN 336
                     |.::.||:|:      :.||....|     |||..:..|:.|  :.|.||:.::..
  Fly   255 LESQLPRLELKRYFETILEGIDWDSKTLLLVADL-----DYLQGLQRLLAEHTSDPMVLSTWLLL 314

  Fly   337 ELLKHFYY-----ERAESVVEQCVSRVRDLF-GEL----LDHMLFEQYED--EGTLKDIYVVWQQ 389
            :|..:|..     ::..:....|:.::|.|. |:|    :..:|.|.|:|  :..::.|.|:::.
  Fly   315 QLPAYFELRLHDDDKLGNQRNHCLEQLRKLMPGQLGRLQMQLVLGESYQDVYDTAIQQIAVLFRD 379

  Fly   390 LQRSFRGVLQNSSA--NWLVPETREQLLEQLNTTSLV----------------INGYAEVNFTQ- 435
            |::.|..||..:..  ..||  ||....::|....|:                :.|..:.|..|
  Fly   380 LKQQFELVLNETEVFNEDLV--TRNLARDKLRAMRLLTPRLQDPINGGPGTPQLGGNCDANLLQL 442

  Fly   436 -------RYEELHLKPRDYLHNLRTILNHQSLRVKVKTQTSVTYDPVG---------KRVLLPVA 484
                   .|.::..:|                      .|||..||:.         .|:.||:.
  Fly   443 SLSQAKLEYRQVFGEP----------------------VTSVPADPLSVNAYYRLKLNRIELPLG 485

  Fly   485 LLQPNFLWSRYY----PKAVRYGSLGTLLAQQLAHSLE------DAS------KWDAKSFAEYSK 533
            |:....:..:..    .:|.....||.:||.::.|:.:      ||:      :|.|::...:..
  Fly   486 LMATPLIQQQCSKEADTRAKLSAGLGYILAHEMVHAFDLDGLNYDATGQLANGQWSARAIIRFGL 550

  Fly   534 RKSCFKEQYGRLRLNGHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQLNLG 598
            |..|:        |...|...:....|||||...:::|...||..        .|:.:|
  Fly   551 RAGCY--------LGVRYSNATLTVNENIADTEGLRLALDTYRHR--------SGATNL------ 593

  Fly   599 SRRLFFLSFAQLWCNDANEQFRDKQSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKC 663
              |.||::|||.||...    .....|.....:|.||...:.|...||..|.|...|:|....||
  Fly   594 --RTFFVAFAQNWCGTV----ASTSGLSQHAGHAERVNNVVGNMPEFGDTFECKATSQMNPVNKC 652

  Fly   664 QLF 666
            .::
  Fly   653 HIW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	158/697 (23%)
Nep6	NP_572831.2	M13	40..653	CDD:341056	156/693 (23%)