Protein Alignment Nepl19 and Nep1

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_511056.2
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Alignment Length: 747
• Identity: 181/747 - (24%)
• Similarity: 325/747 - (43%)
• Gaps: 140/747 - (18%)

  Fly    23 RGHLLTGQPAIDLRIQAREQLISQSNDSAY--------VQRLMRLSKSAEMRSYMQQDADACENF 79
            |.||...:|..|.|...|   .:|.:.||:        .|..:|  .:|.:.|.|..::|.||:|
  Fly   140 RCHLYRLEPDNDDRPNGR---WNQDSGSAHEGQDNICMTQECVR--TAASLLSAMDLNSDPCEDF 199

  Fly    80 YDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQQ----RLMEQPANVETDEVAVLRLKEFYA 140
            :.|:||.|.:::|    .|.:.:.:. ..:..|.:||    .::|:|.: |.|..|.::.|.|:.
  Fly   200 FQYACGTWNKMHP----IPEDRSSIS-TFEVLSDQQQVILRAVLEEPID-ERDNKATIKAKTFFK 258

  Fly   141 SCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEW-PAEEFDWLDTVARIKRQYGFDILLLFQ 204
            ||:...|: ..:...:|::::...|..||:.   :.| |..:......:.:::..|...:::...
  Fly   259 SCMDIPQI-RKIGTGRLKQVLQSLGGWPVIE---RNWSPPADLSVERLMGQLRLNYSEPVMIELY 319

  Fly   205 QSADR-------IYVGQPKQILP---------EANRKAVAEDIANHLERHLGVDPKVAVTTAREI 253
            ..||.       :.:.|.:..||         .||.:.........:...||.||..|.....::
  Fly   320 VGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRRAYHRYMTQVALLLGADPATAAAELEKV 384

  Fly   254 TEFEQKIAAIMV---DRRVG--VMSKLYTPSDADYVDVSKLTQFVETVLDR--ELLANESLYQHV 311
            ..||.::..:.:   ||...  |..|:..|...:.|...:..::::..|..  .|..:|.|..:.
  Fly   385 VLFETQLVNVSLPEADRHDTSLVYRKMLLPELQELVPEVQWQEYLQAALGPGIPLQEDEPLVTYG 449

  Fly   312 PDYLMKIDELVTETPPHVLANYVF----NELLKHFYYERAESVVE----------------QCVS 356
            ..||.::.:::..|...|:.||:.    ..|:.|...|.....||                |||.
  Fly   450 LHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVE 514

  Fly   357 RVRDLFGELLDHML----FEQYEDEGTLKDIYVVWQQLQRSFRGVLQNSSANWLVPETREQLLEQ 417
            ......|..:..:.    |.|...|..|:.|:.:    :.:|..:|..:  :|:..|||....|:
  Fly   515 WTNKKLGVAVGALFIRDNFNQESKEVALEMIHTI----RAAFNELLAEN--DWMDDETRAVAKEK 573

  Fly   418 LNTTSLVINGYAEV--NFT---QRYEELHLKPRDYLHNLRTILNHQS---LRV--------KVKT 466
            .::.:..| ||.|:  |.|   |.|..|.:.|.::::|:.:||..:|   ||:        |..|
  Fly   574 ADSMNERI-GYPELLTNATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTT 637

  Fly   467 QTSVT---YDPVGKRVLLPVALLQPNFLWSRYYPKAVRYGSLGTLLAQQLAHSLEDASK------ 522
            :.:|.   |:|....::.|..:|||.| :|:::||::.||.:|.::..::.|..:|..:
  Fly   638 EPAVVNAFYNPNKNDIVFPAGILQPLF-YSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEG 701

  Fly   523 -----WDAKSFAEYSKRKSCFKEQYGRLRLNGHYLPESDL-------QAENIADNLAIQVAYHAY 575
                 |:..:...:.:|..|..:||.|.::|     |.|:       |.||||||..::.|:.||
  Fly   702 NMMQWWNNATIEAFRERTQCVIDQYSRYKIN-----EVDMFMDGRMTQGENIADNGGLKQAFRAY 761

  Fly   576 RRLLAELDPSFLGSE-SLPQLNLGSRRLFFLSFAQLWC-----NDANEQFRDKQSLFLGTPNALR 634
            ::.     .:..|.| .||.||:...:||||::||:||     .||..:.|..    :.:|..:|
  Fly   762 KKW-----ETLHGREQQLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSA----VHSPGFVR 817

  Fly   635 VLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
            |||.|||.|.|...:.|...|.|...:||.::
  Fly   818 VLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	165/685 (24%)
Nep1	NP_511056.2	M13	194..847	CDD:341056	165/684 (24%)