Protein Alignment Nepl19 and frma

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 709
• Identity: 148/709 - (20%)
• Similarity: 264/709 - (37%)
• Gaps: 221/709 - (31%)

  Fly    64 EMRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQQRLMEQPANVETD 128
            :::|:.|  ||.|:|||..:|||| ..:.|.|:|   .:|:..|...|..|...|::...  |.|
  Fly    18 QVKSHPQ--ADPCQNFYKVACGNW-SASHATDSY---ESFMDRLDYNYQEKLADLLDNER--EDD 74

  Fly   129 EVAVL-RLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEFDWLDTVARIK 192
            |...| :|:.||.:|.  :.:.:|...|.|:.::.                      ::.:...:
  Fly    75 EPHFLQQLRNFYTACR--KPLSQDQVLRILEHLIV----------------------MENIQNEE 115

  Fly   193 RQYGFDILLLFQQSADRIYVGQPKQILPEANRKAVAEDIANHLERHLGVDPKVAVTTAREITEFE 257
            ...|.......|...|          |.::|...:.:.:.:| .:|.  ||.   ||.||
  Fly   116 LSVGLTAAFRLQVLID----------LNDSNTYDIWKQLMSH-RKHW--DPN---TTNRE----- 159

  Fly   258 QKIAAIMVDRRVGVMSKLYTPSDADYVDVSKLTQFVETVLDRELLANESLYQHVPDYLMKID--- 319
             .:...|.|:....:.|:..|....|.              |||   ..|.:.:..|..:.|
  Fly   160 -PLTREMFDKLWASLPKIPFPFKEYYW--------------REL---SELEEKIMSYGSEDDGFD 206

  Fly   320 --ELVTETPPHVL-----ANYVF--------------NELLKHFYYERAESVVE----------- 352
              :|||..||..:     .|..:              ||.:..:.|.|.:.|.|
  Fly   207 SGDLVTRIPPFWMMPWPNGNITYENLSQMAHWLDIKANEFILTYIYMRLKLVAEGVSTESWHIDR 271

  Fly   353 -QCVSRVRDLFGELLDH---MLFE----QYEDEGTLKDIYVVWQQLQRSF-------RGVLQNSS 402
             ||..:.|    ::|.|   .|.|    :.::|..|:||:.   :|::.|       |.....|:
  Fly   272 DQCAEQSR----QILSHPAAWLVEKNHPRLKEEPVLQDIFA---ELKQRFGQKLLANRNNFTRST 329

  Fly   403 ANWLVPETREQLLEQLNTTSLVINGYAEV---NFTQRYEELHLKPRDYLHNLRTILNHQSLRVKV 464
            .::|:.:.:..   :|..:.|..|..|:.   ...:.|.::|:...||..||...|||.....|.
  Fly   330 QHFLLGKLKRM---RLRLSILPRNSSAQSMVRRIERHYRDVHMNASDYFGNLHIGLNHSRSHKKY 391

  Fly   465 K------------------------------TQTSVTYDPVGKRVLLPVALLQPNFLWSRYYPKA 499
            .                              |..|..|......:::|::||:|.| ::...|..
  Fly   392 AQLWAIVFGRQLIPSRISKSDLYPTQVRGYGTYASAFYIVKQNMLIVPLSLLEPPF-YTHGQPSI 455

  Fly   500 VRYGSLGTLLAQQLAHSLEDASKWDAKSFA-----------------EYSKRKSCFKEQYGRLRL 547
            :.|.:||.:|..:|:|..:.    :..:|:                 .:.:...|.:.::||.|.
  Fly   456 LTYSALGFILGHELSHGFDS----EGMTFSSHGVGSSAVDRELDRNPRFQQELGCLRRRFGRKRY 516

  Fly   548 NGHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQLNLGSRRLFFLSFAQLWC 612
                        |..||...:::||.||.. .|:.|..  .:.|..:| :..::.||.:|||.:|
  Fly   517 ------------EKFADASGLELAYSAYFD-TAQTDHK--RNRSAEEL-VTQKQQFFHNFAQFFC 565

  Fly   613 ND-----ANEQFRDKQSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
            :|     |::...|::          ||..|:::|..|...|:||.:.|.   ::|:|:
  Fly   566 SDKELLQAHDHGSDRK----------RVNDAVAHFEPFREAFSCGPSPRR---RQCRLY 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	144/696 (21%)
frma	NP_572226.2	GluZincin	25..601	CDD:472708	142/685 (21%)