Protein Alignment Nepl19 and Kel

DIOPT Version :9

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_001178540.1
• Gene: Kel / 297025
• RGDID: 1565470
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 710
• Identity: 163/710 - (22%)
• Similarity: 268/710 - (37%)
• Gaps: 186/710 - (26%)

  Fly    71 QDADACENFYDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQQRLMEQPA--NVETDEVAVL 133
            :.|..|.:|:.::|      ..||..    :|..|.|.:....:..:|:|.|.  ::|:.|....
  Rat    76 RSAAPCTDFFSFAC------EKANGT----SNSFQALAEENKSRLWKLLEAPGSWHLESGEEKAF 130

  Fly   134 RLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEFDWLDTVARIKRQYG-- 196
               :||.||:....: |......|.:|:.:.|...:    ...|..  ||:...:..:..|||
  Rat   131 ---QFYNSCMDTDAI-EASGTGPLVQIIKELGGWNI----SGNWTF--FDFNQNLRLLMSQYGHF 185

  Fly   197 -------------------------FDILLLFQQSADRIYVGQPKQILPEANRKAVAEDIANHLE 236
                                     |||||. |....::|.    |||    |:.|.  ..|.|.
  Rat   186 PFFRAYLHPHPAPPHTPIIQIDQPEFDILLQ-QDQEQKVYA----QIL----REYVT--YLNRLG 239

  Fly   237 RHLGVDPKVA--------VTTAREITEF----EQKIAAIMVDRRVGVMSKLYTPSDADYVDVSKL 289
            ..||.:|:.|        |.|:| :.:|    :|:.|.   |:...|::.......|..:|....
  Rat   240 TLLGSNPQEAQQHASWSIVFTSR-LFQFLRPQQQQQAQ---DKLFHVVTIDALQEMAPAIDWLSC 300

  Fly   290 TQFVETVLDRELLANESLYQHVPDYLMKIDELVTE---TPPHVLANYV---------------FN 336
            .|.:.|.:  .|..:::|..|..|||..:.:||.|   ....::.:|:               |.
  Rat   301 LQAIFTPM--SLSPSQTLQVHDLDYLRNMSQLVEEGLLNHSEIIQSYMILGLVDTLSPALATKFQ 363

  Fly   337 ELLKHF--------------YYERAESVVEQCVS---------RVRDLFGELLDHMLFEQYEDEG 378
            |..:..              .|.|....|||..|         .|.:.||..:.....|.:.:
  Rat   364 EARRELTQKLRKLKERPPLPAYPRWMKCVEQTGSFFEPTLAALFVHEAFGPSIRSAAMELFAE-- 426

  Fly   379 TLKDIYVVWQQLQRSFRGVLQNSSANWLVPETREQLLEQLNTTSLVINGYAEVNFT----QRYEE 439
             :||..:|  :|::          .:|:..|||::.|.:|....:.:........|    |.|.:
  Rat   427 -IKDAVIV--RLKK----------LSWISEETRKEALNKLTQLQVEMGAPKRALKTEMAKQEYSD 478

  Fly   440 LHLKP---RDYLHNLRTILNHQSLRVKVKTQ-------------TSVTYDPVGKRVLLPVALLQP 488
            :.|.|   :.:|..:|::   |..:|:...|             .|..|......|:.|..||||
  Rat   479 IQLGPSFLQSFLSCVRSL---QGRKVRSFLQPFPYHRWQKSPWSVSAYYSVPDHVVVFPAGLLQP 540

  Fly   489 NFLWSRYYPKAVRYGSLGTLLAQQLAHSL------EDASKWDAKSFAEYSKRKSCFKEQYGRLRL 547
            .| :...||:||.:|::|:::|.:|.|..      ......|.::..|   ...|.:.:|....|
  Rat   541 PF-FHPGYPRAVNFGAVGSIMAHKLLHIFFQFLLPGGCPACDTRALQE---ALLCLEHRYAAFPL 601

  Fly   548 ------NGHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQLNLGSRRLFFLS 606
                  ||     |....||.||...:.:|:.|||:.:.|.    .|..:||...|...:|||.|
  Rat   602 PSMSSFNG-----SHTLLENAADIGGVAIAFQAYRKRITER----TGELTLPNQELSPYQLFFRS 657

  Fly   607 FAQLWCNDANEQFRDKQSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
            :||:.|.:...|  |.|...  :|..|||.|.|||...|.:.|.|.:.|.:....:|:|:
  Rat   658 YAQVMCRELISQ--DPQDTH--SPPRLRVHGPLSNSPDFAKHFLCPSGSLLNPSTRCKLW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	161/699 (23%)
		M13	73..664	CDD:189000	161/704 (23%)
Kel	NP_001178540.1	PepO	75..713	CDD:226118	162/708 (23%)
		M13	78..711	CDD:189000	161/704 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344526
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.810