Protein Alignment Nepl19 and Kel

DIOPT Version :9

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_115929.3
• Gene: Kel / 23925
• MGIID: 1346053
• Length: 713
• Species: Mus musculus
• Alignment Length: 710
• Identity: 153/710 - (21%)
• Similarity: 268/710 - (37%)
• Gaps: 196/710 - (27%)

  Fly    76 CENFYDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQQRLMEQPANVET---DEVAVLRLKE 137
            |.:|:.::|   .:.|..:|::       |.|.:....:..||:|.|.:...   :|.|.    :
Mouse    81 CTDFFSFAC---EKANGTSDSF-------QALTEENKSRLWRLLEAPGSWHLGSGEEKAF----Q 131

  Fly   138 FYASCL-----------LFRQVPEDL-------------YRRQLQEIVADFGRMPVLSLPGQEWP 178
            ||.||:           ...|:.|:|             :.:.|:.:::.:|..|......:..|
Mouse   132 FYNSCMDTDAIEASGSGPLIQIIEELGGWNITGNWTSLDFNQNLRLLMSQYGHFPFFRAYLRPHP 196

  Fly   179 AEEFDWLDTVARIKRQYGFDILLLFQQSADRIYVGQPKQILPEANRKAVAEDIANHLERHLGVDP 243
            |...   ..:.:|. |..|||||. |:...::|.    |||    |:.|.  ..|.|...||.:|
Mouse   197 APPH---TPIIQID-QPEFDILLQ-QEQEQKVYA----QIL----REYVT--YLNRLGTLLGSNP 246

  Fly   244 KVAVTTAREITEFEQKIAAIM-VDRRVGVMSKLYTPSDADYVDVSKLTQFVETV----------L 297
            :.|...|.....|..::...: ..::.....||:     ..|.:.:|.:....:          .
Mouse   247 QEAQQHASWSIVFTSRLFQFLRPQQQQQAQDKLF-----HVVTIDELQEMAPAIDWLSCLQAIFT 306

  Fly   298 DRELLANESLYQHVPDYLMKIDELVTE---TPPHVLANYVFNELL--------KHFYYERAESVV 351
            ...|.::::|..|..|||..:.:||.|   .....:.:|:...|:        ..|...|.|.:.
Mouse   307 PMSLNSSQTLVVHDLDYLRNMSQLVEEGLLNHRESIQSYMILGLVDTLSPALDTKFQEARRELIQ 371

  Fly   352 E-----------------QCVSR-------------VRDLFGELLDHMLFEQYEDEGTLKDIYVV 386
            |                 :||.:             ||:.||..:.....|.:.:   :||..::
Mouse   372 ELRKLKERPPLPAYPRWMKCVEQTGAFFEPTLAALFVREAFGPSIQSAAMELFAE---IKDAVII 433

  Fly   387 WQQLQRSFRGVLQNSSANWLVPETREQLLEQLNTTSLVINGYAEV----NFTQRYEELHLKP--- 444
              :|::          .:|:..||:::.|.:|....:.:......    ..||.|.::.|.|
Mouse   434 --RLKK----------LSWISEETQKEALNKLAQLQVEMGAPKRAVKPDIATQEYNDIQLGPSFL 486

  Fly   445 RDYLHNLRTI--LNHQSLR--------VKVKTQTSVTYDPVGKRVLLPVALLQPNFLWSRYYPKA 499
            :.:|..:|::  .|.||..        .|...:.:..|......|:.|..||||.| :...||:|
Mouse   487 QSFLSCVRSLRARNVQSFLQPFPYHRWQKSPWEVNAYYSISDHMVVFPAGLLQPPF-FHPGYPRA 550

  Fly   500 VRYGSLGTLLAQQL-----------------AHSLEDASKWDAKSFAEYSKRKSCFKEQYGRLRL 547
            |.:|:.|:::|.:|                 .|.|::|              ..|.:..|....|
Mouse   551 VNFGAAGSIMAHELLHIFYQLLLPGGCPACDTHVLQEA--------------LLCLERHYAAFPL 601

  Fly   548 ------NGHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQLNLGSRRLFFLS 606
                  ||     |....||.||...:.:|:.||.:.:.|    ..|..:||.|:|...:|||.|
Mouse   602 PSISSFNG-----SHTLLENAADIGGVAIAFQAYSKRIVE----HTGELTLPNLDLSPYQLFFRS 657

  Fly   607 FAQLWCNDANEQFRDKQSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
            :||:.|...:.|  |.|...  :|.:|||.|.|||...|.:.|:|...:.:....:|:|:
Mouse   658 YAQVMCRGLSSQ--DPQDPH--SPPSLRVHGPLSNTPDFAKHFHCPRGTLLNPSARCKLW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	151/699 (22%)
		M13	73..664	CDD:189000	151/706 (21%)
Kel	NP_115929.3	M13	78..711	CDD:341056	151/706 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841118
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.810