Protein Alignment Nepl19 and nep-25

DIOPT Version :9

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_495164.2
• Gene: nep-25 / 191543
• WormBaseID: WBGene00022874
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 575
• Identity: 100/575 - (17%)
• Similarity: 185/575 - (32%)
• Gaps: 190/575 - (33%)

  Fly   197 FDILLLFQQSADRIYVGQPKQILPEANRKAVAEDIANHLERH--LGVDPKVAVTTAREITEFEQK 259
            |.:.:||..|...:    ||.|:.|            |:::|  ..|||.|         :|...
 Worm    10 FSVFILFCTSKASL----PKNIIQE------------HIKKHADFSVDPCV---------DFYAH 49

  Fly   260 IAAIMVDRRVGVMSKLYTPSDADYVDVSKLTQFVETVLDRELLANESLYQHVPDYLMKIDELVTE 324
            :....|:|        |...|...:....:.::.:              :|     .|.|:...|
 Worm    50 VCPWKVER--------YFMEDLSKLKAGMVAKYRK--------------KH-----PKFDKFKGE 87

  Fly   325 TPPHVLANYVFNELLKHFYYERAESVVEQCVSRVRDLFGELLDHMLFEQYEDEGTLKDIYVVWQQ 389
            ..      :...|.||....|:.:|..:....|:...|....|:...|..:            :.
 Worm    88 DA------FAIAEALKQLNIEQLKSECKPSKPRLSSFFISAQDNRTIENVD------------EV 134

  Fly   390 LQRSFRGVLQNSSANWLVPETREQLLEQLNTTSLV----INGYAEVNFTQRYEELHLKPRDYLHN 450
            |...|........|..::.|..|  :|...||..|    :||:..   ::..|:|.:|.|...:.
 Worm   135 LFPGFENYPCEEKAAIIIKEVGE--IEDYTTTRSVLVSAVNGFIT---SKLVEKLDVKARKLFNK 194

  Fly   451 LRTIL-----------NHQSLRVKVKTQTSVT-----------------YDPVGK--RVLLPVAL 485
            .::::           |::::...|:..:::|                 |:...|  |..|.||.
 Worm   195 FKSVISKEIIKTPWAKNYKAIEQYVEALSNITFRTFADVRITVKKSMELYESTEKDCRKKLDVAF 259

  Fly   486 LQPNF----------------------------------LWSRY--YPKAV-------------- 500
            .||..                                  :|..:  :..:|
 Worm   260 SQPTAELVCKGVATRKAEELLDEPIEDIFPQDQAGILKDVWQMFNSFDNSVYIGNEFLLLLNTDY 324

  Fly   501 ---RYGSLGTLLAQQLAHSLE-DASKWDAKSFAEYSKRKSCFKEQYGRLRLNGHYLPESDLQ--- 558
               .|||:|..:..::.|:|. |.:..|......::|...|.|:|  .|:....:...:::.
 Worm   325 FSDLYGSIGFSMIHEIMHTLVFDDNDLDKPLSKLWTKNADCVKDQ--ALKTCETFPTVTEMHNMK 387

  Fly   559 ---------AENIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQLN-LGSRRLFFLSFAQLWCN 613
                     .|:.||..|.::|:..|       :.|:.....:|... |..::|||...|..:||
 Worm   388 PACNTTVTFEEDAADLAAYRIAWRIY-------ENSYARKTVVPNYEALDKKQLFFYGAAVFFCN 445

  Fly   614 DANEQFRDKQSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTS--PQKCQLF 666
            .........|:| ..:.|..||...:|..:.|...|.|....:|.:  .:.|:|:
 Worm   446 QDGMSRVPFQNL-AHSNNYQRVNSLMSQMKQFSDAFKCKPTDKMITNRAKHCELY 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	97/562 (17%)
		M13	73..664	CDD:189000	98/571 (17%)
nep-25	NP_495164.2	Peptidase_M13	308..496	CDD:279739	39/197 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910