Protein Alignment Nepl19 and nep-24

DIOPT Version :9

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 552
• Identity: 98/552 - (17%)
• Similarity: 194/552 - (35%)
• Gaps: 125/552 - (22%)

  Fly    65 MRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQQRLMEQPANVETDE 129
            :.:|.....|.|:||:.::||...: :...|.|.::|..:..::|.:..|.:....:..|.
 Worm    50 LHNYHDPSVDPCDNFHQFACGREHE-HETEDIYTKKTKTINNIMKRFLKKNETSRSKSENA---- 109

  Fly   130 VAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVAD---FGRMPVLSLPGQEWPAEEFDWLDTVARI 191
                 ::..|.:|....:.......:.||:|..|   .|..||:.   .:|...:||..|.:..:
 Worm   110 -----MRTLYKACKTLEKNSTASRNKALQDIFQDIQSIGAWPVVD---DKWDESKFDLNDFLVNL 166

  Fly   192 ----KRQYGFDILLLFQQSADRIYVG-QPKQILPEA-----------------------NRKAVA 228
                ::.:|     |||.:.   ||. :...|.|||                       |.|.:.
 Worm   167 VRLGRKNFG-----LFQMAR---YVNVRNFAIGPEAAWRHNVDLGKTISEILKANSVQTNNKKLL 223

  Fly   229 EDIANH--LERHLGVDPKVAVTTAREITEFEQKIAAIMVDRRVGVMSKLYTPSDADYVDVSKLTQ 291
            :|:|.:  ||:.|.......|......:|....::::...|.|           .:.:...|.|.
 Worm   224 DDLAEYVNLEKALSQHKFNTVQPGYIFSERSDFVSSVNFSRLV-----------LEMMSPDKRTL 277

  Fly   292 FVETVLDRELLANESLYQHVPDYLMKIDELVTETPPHVLANYVFNELLKHFYYERAESVVEQ--- 353
            |.| |.....|.|.||:....:   .::.::..|....||||:..:.:.       .|:.:.
 Worm   278 FPE-VYQIMYLTNTSLFFGKNN---NLETIIRNTSKRALANYLIFKFID-------TSIADLTYG 331

  Fly   354 -----CVSRVRDLFGELLDHMLFEQYEDEGTLKDIYVVWQQLQRSFRGVLQNSSANWLVPETREQ 413
                 |..:|.:..........:..:..:...|.|..:.:..|.....::  .:.:|:..::::.
 Worm   332 SPSAFCEQKVINFLPRAALRAFYRNFISKENRKKITKLTEATQVQLLKII--GATDWMSIKSKKI 394

  Fly   414 LLEQLNTTSLVINGYAEV-----NFTQRYEELHLKPRDYLHNLRTILNHQSLRVKVKTQT-SVTY 472
            .::::::.::|| ||.:.     .....:|.|:|...|..:.:...:|......::...| .|.|
 Worm   395 AMDRVSSMNMVI-GYPDYFDPPGKLDGLFEHLNLSSSDTYYTVVRKINRFMREQEMDYYTGEVPY 458

  Fly   473 DPVGKRVLLP--------------VALLQPNF---LWSRYYPKAVRYGSLGTLLAQQLAHSLE-- 518
            .|     |.|              :.:..|.|   .:...:|...........||.::.|:..
 Worm   459 YP-----LFPGLMTNAMYNANDNNLMIFAPFFDDPFFDSSFPDYANIAFTSNTLAHEMGHTFSPH 518

  Fly   519 -------DASKW-DAKSFAEYSKRKSCFKEQY 542
                   ....| ..|...||.||..|.::||
 Worm   519 LMDIMTGTTEVWLTPKETEEYEKRVKCLEDQY 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	98/550 (18%)
		M13	73..664	CDD:189000	97/544 (18%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:301352	97/544 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920