Protein Alignment Nepl19 and nep-20

DIOPT Version :9

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_001317749.1
• Gene: nep-20 / 188176
• WormBaseID: WBGene00020293
• Length: 834
• Species: Caenorhabditis elegans
• Alignment Length: 688
• Identity: 138/688 - (20%)
• Similarity: 264/688 - (38%)
• Gaps: 164/688 - (23%)

  Fly    64 EMRSYMQQDADACENFYDYSCGNWPQ---INPANDAYPRETNFVQLLLKAYSHKQQRLMEQPANV 125
            |:.:|.......|.|||..:||.:..   ::...||..:|.  |:.:::.:      |....:::
 Worm   226 ELSAYQDTSVSKCHNFYKATCGKYKHHQALDKHRDAKKKEV--VKRIVREF------LRRNESSI 282

  Fly   126 ETDEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEFDWLDTVAR 190
            .:.....:||  .:..|..|.|      .:...:|..|..::       ..||..:.||:|.:..
 Worm   283 TSKFEPAIRL--MFGKCNKFSQ------NKTYLDIFKDIEKI-------GPWPVLKSDWVDVMFN 332

  Fly   191 IKR------QYGFDILLLFQQSADRIYVGQPKQILPEANRKAVAEDIANHLERHL-------GV- 241
            :..      :.||....||:....::..||...|.|...::      .|.||:.:       ||
 Worm   333 LNDYLLSLVELGFTDFGLFKLEFRQLAFGQFPVIAPSEQKQ------GNQLEKIILEILEANGVQ 391

  Fly   242 -DPKVAVTTAREITEFEQKIAAIMVDRRVGVMSKL--YTPSDADYVDVSKLTQ----------FV 293
             |.:......||.:||:.::..:.::   |...|.  |..|... |::|.|.|          .|
 Worm   392 ADRQKLSKYLREYSEFKSQLRHMSLE---GTSVKYIRYNASTLS-VNISALVQKMAPMSTSSGLV 452

  Fly   294 ETVLDRELLANESLYQHVPDYLMKIDELVTETPPHVLANYVFNELLKHFYYERAESVVEQCVSRV 358
            ..:....|:.|.|.:     :...:|.::.:|....||||    |:.||    .::|.....|..
 Worm   453 RRIQSGILITNSSSF-----FGKNLDAIIQQTHKRTLANY----LIFHF----IDAVTFDLTSGA 504

  Fly   359 RDLFGELLD-------HMLFEQY---EDEGTLKDIYVVWQQLQRSFRGVLQNSSA---NWLVPET 410
            :.....|:|       .:|.:.:   ||:|.:.::.   :.|::....::...|:   ..||.|.
 Worm   505 KHSEHTLIDLLPRGSLQVLSQDFVDEEDQGVMVEMA---KDLKKHVVEMISEGSSLDKGHLVFEE 566

  Fly   411 RE--QLLEQLNTTSLVINGYAEVNFTQRYEELHLKPRDYLHNLRTILNHQSLRVKVKTQTSVTY- 472
            :|  :|:.::... ||:..|......|.:|:|:|...|.||.:     .|.|| :.:::..:.|
 Worm   567 KERRKLIRKVQDI-LVVTKYPLEILNQNFEKLNLTYSDSLHKI-----IQKLR-RFRSEQLIEYL 624

  Fly   473 ----DPVGKRV------------LLPVALLQPNFLWSRYYPKAVRYGSLGTLLAQQLAHSLED-- 519
                ||..|.:            |:.:|.:.....:...||..|....:|.:::::|..||:.
 Worm   625 GGDLDPTDKGMWGSAHYEQATNDLIIIAPIIDGPYFDTSYPNYVNIFFMGFIISRELGRSLDSVR 689

  Fly   520 --------ASKW-DAKSFAEYSKRKSCFKEQY-GRLRLNGHYLPESDLQAENIADNLAIQVAYHA 574
                    ...| .::|...:.....|::::. |...||           |.:||::..:.::.|
 Worm   690 IRKDEKGHTENWLKSESLKRFDNNVKCWRKKITGTRFLN-----------EMLADHVGHEASFMA 743

  Fly   575 YRRLLAELDPSFL----GSES--LPQLNLGSRRLFFL-----SFAQLWCNDANEQFRDKQSLFLG 628
            .::...|::.:.:    |.||  :.|:....:.|:|.     |..:|...||.:.:
 Worm   744 LKKWEKEMNGTIVEKIRGYESMTMEQIFFHLQALYFCRPPGGSTGELTAKDARQHY--------- 799

  Fly   629 TPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
               :.||..|..|...|.:.|.|.:...|.|..||..|
 Worm   800 ---STRVNEAFKNMPQFAKAFGCSSNQNMNSKTKCTFF 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	132/674 (20%)
		M13	73..664	CDD:189000	134/675 (20%)
nep-20	NP_001317749.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920