Protein Alignment Nepl19 and nep-21

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_001360525.1
• Gene: nep-21 / 179925
• WormBaseID: WBGene00011794
• Length: 864
• Species: Caenorhabditis elegans
• Alignment Length: 793
• Identity: 187/793 - (23%)
• Similarity: 316/793 - (39%)
• Gaps: 188/793 - (23%)

  Fly     9 ALLQLLLLHL-VGSGRGHLLTGQPAIDLRIQAREQLISQS----NDSAYVQR-LMRLSKSAEMRS 67
            |||.:|.|.| |..|......|:|...|..:.....:.:|    ||.....| .:||  :..:..
 Worm   125 ALLSVLFLWLWVLDGYKTFTDGRPIYPLPFENSSVAVDRSAKNHNDVVCTSRECVRL--AGFLAE 187

  Fly    68 YMQQDADACENFYDYSCGNWPQIN---PANDAYPRETNFVQLLLKAYSHKQQRLMEQ---PANVE 126
            .:....:.||:||:::|||: .:|   |||.......:.||..|    :||.:.|.|   .||.:
 Worm   188 NLNSKINPCEDFYEFACGNY-GLNKNLPANKPLRHTISDVQSRL----NKQVKSMLQSPISANEK 247

  Fly   127 T-DEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEFDWLDTVAR 190
            . |:||    |.:|..||...:: |......:::|....|..|  :|.|.:|......|.:.:|.
 Worm   248 PWDKVA----KGYYQKCLDEEEL-ESTGVEAMRDIAKRIGGWP--TLEGDKWQEWSHSWEEQIAL 305

  Fly   191 IKRQYGFDILLL--------FQQSADRIYVGQPK-------QILPEAN------------RKAVA 228
            :....|.:.::|        ...|...|.:.|||       ..|..||            ..|||
 Worm   306 VLNLTGVNAVILEMAVTHDPSNSSRSVIELDQPKWGAGSRYPYLSGANDPMLRNYTTLMKMTAVA 370

  Fly   229 EDIANHLERHLGVDPKVAVTTAREITEFEQKIAAIMVD-------RRVGVMSKLY-TPSDADYVD 285
                      ||.||.:|.....|..|||.|:.....|       .|.....:|: ..|...:::
 Worm   371 ----------LGADPAIAEKEMNEAMEFELKLVNFSADDMVRRDPERGNNRFELWQLKSVFPFIN 425

  Fly   286 VSKLTQFVETVLDRELLA---NESLYQHVPDYLMKIDELVTETPPHVLANYV------------- 334
            ..|   :::||. :||:|   |.::.....||.:.|..::..||..|||||:
 Worm   426 FEK---YLKTVF-KELVALSPNHTVIVREIDYFVGIQHVLQSTPKRVLANYISWRLVQGGPTGDY 486

  Fly   335 --FNELL-----KHFYYERAESV----------VEQCVSR---VRDL-FGELLDHMLFEQYEDEG 378
              |:..|     :.||..:|...          .|.||:.   :.|: .|.|.....||:   |.
 Worm   487 FSFSPFLPPSAREPFYQFKANQTGMFNSPPPDRWEDCVTLSVIMMDMPVGRLFVENFFEK---ER 548

  Fly   379 TLKDIYVVWQQLQRSFRGVLQNSSANWLVPETREQLLEQLNTTSLVINGYAEVNFTQRYEE---- 439
            .:|.:..:...|:..|  :.|....:|:...||.:.:.:.|..... :|:..|.|...:.|
 Worm   549 AMKKMTELTSYLKNEF--IKQLHVLDWMDEITRRRAISKANMIEYK-SGFPMVLFNDTWMEKNWG 610

  Fly   440 LHLKPRDYLHNLRTILNHQSLRVKV----------------------KTQTSVTYDPVGKRVLLP 482
            :.:|||:|       |.|.::|||:                      ..|....|.|....::.|
 Worm   611 MIIKPREY-------LLHLTIRVKLVRFTEELLRLDQPLDRSMWFQSPAQVDAYYAPNNNEMIFP 668

  Fly   483 VALLQPNFLWSRYYPKAVRYGSLGTLLAQQLAHSLEDASK-----------WDAKSFAEYSKRKS 536
            ..::|..|| :...|..:.||.:|.::..:::|:.:|...           |||::..::.::..
 Worm   669 AGIMQFPFL-TLGVPNYITYGMVGAVIGHEVSHAFDDQGGQYDEMGNLNDWWDAETEEKFIEKTR 732

  Fly   537 CFKEQYGRLRLNGHYLPESDLQ-------AENIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQ 594
            ||..||..:     ::.|:|:.       .||||||..::.|::||:..  :.:.:.:...:||.
 Worm   733 CFVRQYENV-----HVVEADIHLNGQLSLGENIADNGGVKTAFNAYKAW--KSNTTGISEPALPG 790

  Fly   595 L-NLGSRRLFFLSFAQLWCNDANEQFRDKQSLFL-----GTPNALRVLGALSNFRAFGRDFNCGT 653
            . |..|:::|||::|..||:    ..|.|..:.:     ..|:..|.:..|.|...|.:.|.|..
 Worm   791 FQNFTSQQMFFLAYANNWCS----LVRPKHYIQIILTDVHAPSKYRAMIPLQNRPEFAKAFQCPI 851

  Fly   654 ASRMTSPQKCQLF 666
            .|.|...:|||::
 Worm   852 GSPMNPERKCQVW 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	168/719 (23%)
nep-21	NP_001360525.1	M13	193..862	CDD:341056	168/719 (23%)