Protein Alignment Nepl19 and nep-23

DIOPT Version :9

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_503004.2
• Gene: nep-23 / 178472
• WormBaseID: WBGene00013785
• Length: 714
• Species: Caenorhabditis elegans
• Alignment Length: 674
• Identity: 141/674 - (20%)
• Similarity: 265/674 - (39%)
• Gaps: 117/674 - (17%)

  Fly    64 EMRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQQRLMEQPANVETD 128
            ::.:|....||.|:|||...||...:.:..:....:......|:.:..::::    ..|.:...:
 Worm    87 QLHNYHDPSADPCDNFYQSVCGKQHEHSLKSGLAKKHLILRNLIRETITNRK----VTPTSKSEN 147

  Fly   129 EVAVLRLKEFYASCLLFRQV--PEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEFDW------- 184
            |     :::|:..|..:::.  ..|:.::.|::|..|     |.|:  ..|||...:|
 Worm   148 E-----MRKFHGICSKYQRANSSSDIAQQALRDIFRD-----VQSI--GSWPAGSRNWNESDFNL 200

  Fly   185 ---LDTVARI-KRQYGFDILLLFQQS---ADRIYVGQPKQILPEANRKAVAEDIANHLERHLGVD 242
               |:.:.:: :|.:|     |||.|   .|::.:...:.   ..|...:...|.|..|.: |:.
 Worm   201 NEMLNNLVKLGQRNFG-----LFQISFKYRDQLLISAEEH---RRNYSKLEPTILNIFETN-GLV 256

  Fly   243 PKVAVTTAREITEFEQKIAAIMVDRRVGVMSKL-------YTPSDADYVDVSK--LTQFVETVLD 298
            |. .:...:::..|....|.:.....:..|.|:       ..|| .|::.:.|  ::...|.::.
 Worm   257 PD-RIQLLKDLEGFASLEALLKNHYYLDNMDKMKPAVLDDLVPS-VDFMGLVKAMISPGKEHLMP 319

  Fly   299 R-EL---LANESLYQHVPDYLMKIDELVTETPPHVLANY-VFNEL---LKHFYYERAESVVEQCV 355
            : ||   :.|::|:.   |..|.::.::.:||...|||| :||.:   |.|..:|........|.
 Worm   320 KIELKTSVLNQTLFN---DENMNLEAIILDTPKRTLANYLIFNFIDSSLDHLVFETTSQKGNTCE 381

  Fly   356 SRVRDLFGELLDHMLFEQYEDEGTLKDIYVVWQQLQRSFRGVLQNSSANWLVPETREQLLEQLNT 420
            .:|..........:....|.|:.....|..:.::.:.:...::|||:  ||..|:::..|:::|.
 Worm   382 DKVITYLPRASLRVFIRNYVDKENRDLITQLAEKTRIALHTLVQNST--WLKAESKQLALDKINA 444

  Fly   421 TSLVINGYAEV-----NFTQRYEELHLKPRDYLHNLRTILNHQSLRVKVKTQTSVT-YDP----- 474
            ...:| ||.:.     .....::.|:|...|..:.....|....:..|:......| .||
 Worm   445 MGKMI-GYPDFFEPPGTLDGMFKNLNLDSSDTYYTALNKLERYFVEQKMDYFAEETPLDPDLRVF 508

  Fly   475 -VGKRVLLP---VALLQPNF---LWSRYYPKAVRYGSLGTLLAQQLAH---------SLEDASKW 523
             :.....:|   :..|.|.|   ::...||..|.....|.::..::.|         ::.....|
 Worm   509 EMNAYYYIPGNQLNFLAPFFDDPMFDSTYPDYVNIAMSGNIIGHEMGHAFGPHAILRTVRGREVW 573

  Fly   524 -DAKSFAEYSKRKSCFKEQY--------GRLRLNGHYLPESDLQAENIADNLAIQVAYHAYRRLL 579
             ..:..|||..|..|...||        ||:...|..:.|.      :|||:..:|::..::.|.
 Worm   574 MKPEELAEYESRAQCLANQYSEYDDPDFGRVFDGGKVIDEL------VADNIGREVSWKMFKSLD 632

  Fly   580 AELDPSFLGSESLPQLNLGSRRLFFLSFAQLWCNDANEQFRD-KQSLFLGTP-NALRVLGALSNF 642
            .......:|.|     :....:|:|...|...|..  ...|| |.|:....| .|.||.|..:|.
 Worm   633 LTNATRIIGFE-----DYDIDQLYFRVGALTHCTP--HAMRDLKGSIESSHPRKAFRVNGVYANL 690

  Fly   643 RAFGRDFNCGTASRMTSPQKCQLF 666
            ..|.|.|||.|.|.|...:||.:|
 Worm   691 PEFARAFNCPTGSPMNPRKKCDMF 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	137/660 (21%)
		M13	73..664	CDD:189000	138/661 (21%)
nep-23	NP_503004.2	M13	96..711	CDD:189000	137/660 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920