Protein Alignment Nepl19 and nep-16

DIOPT Version :9

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_001023203.2
• Gene: nep-16 / 177541
• WormBaseID: WBGene00018472
• Length: 868
• Species: Caenorhabditis elegans
• Alignment Length: 690
• Identity: 131/690 - (18%)
• Similarity: 251/690 - (36%)
• Gaps: 159/690 - (23%)

  Fly    65 MRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQQRLMEQPANVETDE 129
            :.|.:..:.:.|||||.|||..:     .:....::.:|:..|      |.:.|....:.:.::|
 Worm   246 LSSCIDDEIEPCENFYRYSCQRY-----HSQTADKQMSFLSQL------KDESLRRMHSLLSSEE 299

  Fly   130 VAVL-----RL-KEFYASC----LLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEFDW 184
            .:.|     || :..|::|    |.....|.||.     ..:.:|...|:|. ..|.:.|:.:.|
 Worm   300 DSRLLPKSARLSRSLYSACMNAVLRSSNAPTDLL-----TFIRNFPCGPLLR-DCQNFHADSYSW 358

  Fly   185 LDTVARIKRQYGFDILLLFQQSADRIYVGQPKQILPEANRKAVAEDIANHLERHLGVDPKVAVTT 249
            ......:....|...|:::.           :.:.|:...|.:.:.....|...:|:..:..:..
 Worm   359 ERHAGMLDWYAGRYNLIVYD-----------RDVHPQDRSKIILQIKPPDLTPIVGLIERDLIDL 412

  Fly   250 AR-EITEFE-------------------------------QKIAAIMVDRRVGVMSKLYTPSDAD 282
            || ..||||                               .::|.:|||..:..........:..
 Worm   413 ARPSPTEFEPLLQLSLRQNLLSAFARDSLLRDPRDVQSQLDEVARLMVDLYISARQSASLTPNTT 477

  Fly   283 YVDVSKLTQFVETVLDRELLANE-------------SLYQHVPDYLMKIDELVTETPPHVLANYV 334
            |:.:.::.|.:..:..||.|..:             |:..:  ||..::.:::.:|....:|||:
 Worm   478 YMTIGEMFQALPQLYLREFLDAQLSNTYRWTETDMLSIQDY--DYFARLSDIMAQTSRQAVANYL 540

  Fly   335 FN----ELLKHFYYERAESVVEQCVSRVRDLFGELLDHMLFEQYEDEGTLKDIYVVWQQLQRSFR 395
            ..    .|.::.|..|.:....:||.::...  |:...|..::......|..|....|.|:..|.
 Worm   541 LTVTVWNLKQYSYSPRDQYGWRECVDQISSF--EIGRKMYVDKASQTIDLPKIQEFLQNLKIDFL 603

  Fly   396 GVLQNSSANWLVPETREQLLEQLNTTSLVINGYAEVNFTQRY--EELHLKP-------------- 444
            .|.::         |..|.|..:|.....      |.|.:|.  |||..||
 Worm   604 SVHRS---------TPLQYLSNINRLGFY------VGFPRRLQNEELIWKPVSQVSLNETDYFDS 653

  Fly   445 --------RDY-LHNLRTILNHQSLRVKVKTQTSVTYDPVGKRVLLPVALLQPN-FLWSRYYPKA 499
                    ||| :..:.|.|::........:..::.|:.....:::|:|.::|. :|.....|..
 Worm   654 MIRVGKAERDYTMSQIGTYLDNDDTTTFPISDPTMLYNSNVGAIVIPLAFIEPPIYLPGDEVPMY 718

  Fly   500 VRYGSLGTLLAQQLAHSLEDASKWDAKSFAEYSKRKSCFKEQY-GRLRLNGHYLP--ESDLQAE- 560
            ..|.|||....|.::...     |..   .:.:.:..|....: |.|..|....|  |.:|.|.
 Worm   719 GIYSSLGITTLQMISKVF-----WQG---LDKTSQLECLDNVFRGFLDANRQRSPNIEPELLATI 775

  Fly   561 NIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQL-NLGSRRLFFLSFAQLWCN-DANEQFRDKQ 623
            .:||  |.:.|.::|.:.  :.|......::||.. :..|.|...|:|:.::|: :.:|...|.:
 Worm   776 ELAD--AFKSALYSYAKW--QNDHHIHHEKTLPAFDSTDSMRSLMLTFSTMFCSGEGSEPGSDYE 836

  Fly   624 SLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKC 663
            ::         :.....|.|.|...|||..:||:.:.:.|
 Worm   837 AM---------INTVAENSRMFSIHFNCNNSSRLYNRRTC 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	129/680 (19%)
		M13	73..664	CDD:189000	130/682 (19%)
nep-16	NP_001023203.2	GluZincin	254..>725	CDD:387391	94/517 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010