Protein Alignment Nepl19 and nep-26

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_001022540.1
• Gene: nep-26 / 174593
• WormBaseID: WBGene00014171
• Length: 807
• Species: Caenorhabditis elegans
• Alignment Length: 811
• Identity: 168/811 - (20%)
• Similarity: 293/811 - (36%)
• Gaps: 231/811 - (28%)

  Fly    28 TGQPAIDLRIQAREQLISQSNDS---------------------AYVQRLMRLSKSAEMRS---- 67
            ||||:..   :::|.:.|.|...                     .|.|.|...|:...|.:
 Worm    56 TGQPSSS---RSKEAISSSSKGCLLLTVLVIFLFVTLSFAIACFLYYQTLPCTSEECVMTASRLL 117

  Fly    68 -YMQQDADACENFYDYSCGNWPQINPA--------NDAYPRETNFVQLLLKAYSHKQQRLMEQPA 123
             .:.|..:.|:|||.::||.|  ||.:        |..|..:......:::|...........|.
 Worm   118 KRVDQSVEPCDNFYQFACGGW--INQSVNLKYDSWNTLYETQRTAHDQIVQAMHKINDGSYPLPT 180

  Fly   124 NVETDEVAVLRLKEFYASCL---LFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEFD-W 184
            |......|     :.|..|:   ...|....|:.|.:.|:   .|.||.|.....| ..|.|: .
 Worm   181 NAGERAAA-----KMYEQCMDTDTLEQTGLHLWERFVDEL---GGWMPELKNGALE-QEESFEIE 236

  Fly   185 LDTVARIKRQYGF-DILL---------LFQQSAD-----------RIYVGQPKQILPEA---NRK 225
            ||...:.:|::.. ||:|         ||....:           .||...|..:.||.   |::
 Worm   237 LDEDEKKRRRFEIEDIILSAFNYSVFPLFWAGVEVNYLNSKEHLITIYEQLPILLAPEKYHYNKE 301

  Fly   226 AVAEDIANHLERHLGVDPKVAVTTAREITEFEQKIAAIM----VDRRVGVM-------------- 272
            ...|.|...:|     .|.|    .|.:.:..::::|::    .|.:|.:|
 Worm   302 LTPEMIYGKME-----GPPV----TRALQQVGEELSAVLGFDSTDEKVRMMIANMIYLEYQITMA 357

  Fly   273 -SKLYTPSDADYVDVSK---------------LTQFV-ETVLDRELLANESLYQHVPDYLMKIDE 320
             |..|......|..|..               |::.| |.:...|.:|.::..|.:|.....:::
 Worm   358 GSTFYKEKKERYTVVMLRELQEIAPAINWHYFLSRLVGENLSHSEPIALKTGTQWIPILSAIVEK 422

  Fly   321 L-VTETPPHVLANYV-FNELLKHFYYE------------------RAESVVEQCVSRVRDLFG-- 363
            | .:.:...||.||| :..::.|..|.                  .|....|.||.|:..:|.
 Worm   423 LKQSRSGVAVLKNYVKWKTIMFHLAYASPKCRDGLLWMAVSLYSGAASQRKEFCVLRLSGIFPLS 487

  Fly   364 --------ELLDHMLFEQYEDEGTLKDIYVVWQQLQRSFRGVLQNSSANWLVPETREQLLEQLNT 420
                    :.:||       .|..:|.:..:..::|..:..::::|:. :...||||.:::::|.
 Worm   488 LPSILRKIDGIDH-------TEKNVKAVQNIADRIQEKYEEMVRSSNL-FSDRETRENVIDKVNN 544

  Fly   421 TSLVINGYAEVNFTQRYEELHLKPRDYLHNLRTILNHQSLRVKVKTQTSVTYDPVGKRVLLPV-- 483
            .:..| |:.:.           ...||......:..|.:|...:...:|..|....:|:.|||
 Worm   545 MTKFI-GFPDA-----------MRSDYEMEKEAVRLHDTLFWSMVLGSSSVYKERLQRLRLPVDP 597

  Fly   484 --------ALLQPNFLWSR----------YYPKA-------VRYGSLGTLLAQQLAHSLEDASK- 522
                    |:..|...:.|          ..|.|       ..|..:||::..:|.|:.:...|
 Worm   598 RSWVDTRPAISVPAHNYERNLVQIPFDSLRLPYADEHQLDFANYAGIGTIIGHELTHAFDGQGKL 662

  Fly   523 ----------WDAKSFAEYSKRKSCFKEQYGRLRLNGHYLPESDLQA------ENIADNLAIQVA 571
                      |...|..|:..|:.||.:||..| ::.|     |:.|      |||||.:.::||
 Worm   663 HGPTGNLGVWWSTDSIREFKAREQCFVKQYAGL-MDSH-----DMNAAKEGLYENIADQVGLKVA 721

  Fly   572 YHAYRRLLAELDPSFLGSESLPQLNLGSR-RLFFLSFAQLWCNDANEQFRDKQSLFLGTPNALRV 635
            |.|::      ......|..:|.|...|: :||||::.|.||...::.::.:..:    ...:|:
 Worm   722 YEAWK------SNGNQNSGRMPGLEKYSQDQLFFLAYTQGWCALRSKSYKLQPHM----EERIRM 776

  Fly   636 LGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
            ||:|.|...|...:.|.:.|.|..|.||.::
 Worm   777 LGSLQNSPEFASAWKCSSESFMNPPDKCSIW 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	154/736 (21%)
nep-26	NP_001022540.1	M13	124..805	CDD:341056	154/736 (21%)