Protein Alignment Nepl19 and nep-3

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_494679.2
• Gene: nep-3 / 173730
• WormBaseID: WBGene00016778
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 659
• Identity: 134/659 - (20%)
• Similarity: 251/659 - (38%)
• Gaps: 153/659 - (23%)

  Fly    64 EMRSYMQQDADACENFYDYSCGNWPQINPANDA-YPRETNFVQLLLKAYSHKQQRLMEQPANVET 127
            ::.::.....|.|||||..:||.:.:.|..:.: ..::...|:.|::.:.||.|....:..|
 Worm    73 QLLNFQDPSVDPCENFYQAACGKYNEHNVIDGSRTAQKQQIVKRLIRDFLHKNQSSTSKSEN--- 134

  Fly   128 DEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEI---VADFGRMPVLSLPGQEWPAEEFDWLDTVA 189
                  .:|..|..|...:.:.....:..||||   :...|..|||.   :.|..::|:..:.:.
 Worm   135 ------SMKLLYEKCKEAKTIKVLGNQNLLQEIFMNIQKIGSWPVLD---ENWDGKKFNLNEMLL 190

  Fly   190 RIKR----QYGFDILLLFQQSADRIYVGQPKQILPEANRKAVAEDIANHLER-HLGVDPKVAVTT 249
            .:.|    .:||..:::   |:|.....:|.:..|      ..|::::.:.: .||
 Worm   191 SLIRLGVSNFGFFEIII---SSDAFVEIKPARNFP------TRENLSDIISKVFLG--------- 237

  Fly   250 AREITEFEQKIAAIMVDRRVGVMSKLYTPSDADYVDVSKLTQFVETVLDRELLANESLYQHVPDY 314
                ..|:..|.||..|.|.                                      |:::...
 Worm   238 ----NGFQPNITAIENDLRE--------------------------------------YENLQRE 260

  Fly   315 LMKIDELVTETPPHVLANYVFNELLKHFYYERAESVVEQCVSRVRDLFGELLDHMLFEQYEDEGT 379
            |..::.|:..||...|.||:....||....|......|||...|.|........:..:.:.|:..
 Worm   261 LKSLERLIQTTPNRSLVNYLIFNYLKSVMLEYKRLPEEQCEGVVIDFLPRASTRVFVQNFLDKEN 325

  Fly   380 LKDIYVVWQQLQRSFRGVLQNSSANWLVPETREQLLEQL-NTTSLVINGYAEV-----NFTQRYE 438
            .|.:..:.:.::..|..::|.|:  ||..|:::..:::: |..|::  ||.:.     ...:.::
 Worm   326 RKYVAGMIEDVKMGFIDMIQEST--WLNEESKKVAVQKVKNIKSMI--GYPDFFEPPGTLDRSFK 386

  Fly   439 ELHLKPRDYLH----NLRTILNHQSLRVKVKTQTSVTYDPVGKRVLLP----------VALLQP- 488
            :|:::..|..|    .::...|.|.:..   ..:.:..||  ::.:|.          :|:|.|
 Worm   387 DLNIEQTDSYHTIVRKIQKFTNEQCMEF---VASEIPLDP--RQPILHANAFYQNTNFLAILAPV 446

  Fly   489 --NFLWSRYYPKAVRYGSLGTLLAQQLAHSL-------EDASK---W-DAKSFAEYSKRKSCFKE 540
              :.::...:|:.|....:|.:||.::.|:.       :||.:   | ..:...||.||..|...
 Worm   447 LDDPIFDTTFPRYVNLAVIGNVLAHEIGHAFDHTGINYDDAGQQRIWLTPEDSEEYGKRLRCLLR 511

  Fly   541 Q--------YGRLRLNGHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQLNL 597
            |        :|| .|||     |....|..||...::.|:..:::|....:...:|.:     |.
 Worm   512 QHDEYDDPDFGR-NLNG-----SKTLHEISADRFGVEAAWRTFKKLDLSNESEIVGFQ-----NF 565

  Fly   598 GSRRLFFLSFAQLWCNDANEQFRDKQSLFLG-----TPNALRVLGALSNFRAFGRDFNCGTASRM 657
            ...:|:|.:.|.:||..     ||...|...     ..|..||.|..:|...|...|||...|.|
 Worm   566 NIDQLYFRTAALIWCRQ-----RDTTDLQYALQREHPTNNFRVNGIYANMPQFAETFNCPLGSPM 625

  Fly   658 TSPQKCQLF 666
            ...:||.||
 Worm   626 NPKKKCDLF 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	131/646 (20%)
nep-3	NP_494679.2	M13	82..631	CDD:341056	130/645 (20%)