Protein Alignment Nepl19 and nep-11

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_494538.1
• Gene: nep-11 / 173685
• WormBaseID: WBGene00017557
• Length: 848
• Species: Caenorhabditis elegans
• Alignment Length: 719
• Identity: 167/719 - (23%)
• Similarity: 287/719 - (39%)
• Gaps: 174/719 - (24%)

  Fly    69 MQQDADACENFYDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQQR-----LMEQPANVETD 128
            |....|.|::|::::||.|      ||.:|...:.......||:.:|.|     |:||....|::
 Worm   177 MNTSVDPCDDFFEFACGQW------NDQHPIPDDMYGFGTFAYAREQVRQQLRVLLEQEVVTESE 235

  Fly   129 EVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEFDWLDTVARIKR 193
            .:.:.|..  |.||:...|: ::|....|.|.:.:.|..|:|.   :.|...:|::...:...:|
 Worm   236 SINMARAT--YRSCMNKTQL-DELMTGPLFETLTELGEWPLLQ---ENWDKTKFNFTSLLVNSRR 294

  Fly   194 QYGFDILLLFQ---------QSADRIYVGQPKQILPEANR----------------KAVAEDIAN 233
            .||.|:  .||         .|.:.:::.|....|....|                :.....||:
 Worm   295 DYGVDV--FFQLYIYADSKNTSRNTLFIDQSTLALGRGTRDYYLNTTLFSSHMTAYRKYLRQIAH 357

  Fly   234 HL---------ERHLGVDPKVAVTTAREITEFEQKIAAIMV---DRRVGVMSKLYTP-------- 278
            .|         |..:..|       ..:|.:||.::|.|:|   :||..  ::||..
 Worm   358 LLKTDGNLTRSESEMNAD-------IEKIIDFEIELAKIIVAEDERRNN--TRLYNKRQIQDLYN 413

  Fly   279 --SDADYVDV------SKLTQFVETVLDRELLANESLYQHVPDYLMKIDELVTETPPHVLANYVF 335
              ...|:|..      |.||.....  :.|::..|.      :||..:.||:.:|...:|.|||.
 Worm   414 LLPQVDWVPFFQSIAPSDLTHLFHN--ETEIIICEI------EYLQHVSELIEKTDVGLLTNYVL 470

  Fly   336 NELLK---HFYYERAESV----------VEQCVSRVRD-----------LFGELLDHMLFEQYED 376
            ..:::   .:..||.|.:          .:|...|.:|           ..|.:.....|::.:.
 Worm   471 WRVVQSNVRYLDERFEDIKQDFLKVMTGQQQSPPRWKDCAQVPSTVLPLAAGAIYVQAHFQESDK 535

  Fly   377 EGTLKDIYVVWQQLQRSFRGVLQNSSANWLVPETREQLLEQLNTTSLVIN-GYAEV-----NFTQ 435
            ...|:.|    ..|:.||..:::.:  :|:..||:...:|:.|  |::.| ||.:|     ...:
 Worm   536 HEALRMI----MHLRNSFADLVRQN--DWMDEETKAVAIEKAN--SMINNIGYPDVTNDLPKLDK 592

  Fly   436 RYEELHLKPRD--YLHNLRTILNHQSLRVKVKTQ-------------TSVTYDPVGKRVLLPVAL 485
            :|..|.:...|  |....::::..||...:..|:             .:..|.|....:..|..:
 Worm   593 QYLGLSISDSDTYYYIMKKSVVWMQSREFQKLTKPFDKHEFDISPAVVNAFYSPEKNAITFPAGI 657

  Fly   486 LQPNFLWSRYYPKAVRYGSLGTLLAQQLAHSLEDASK-----------WDAKSFAEYSKRKSCFK 539
            |||.| :|..:||||.||::|.::..::.|..:|...           |...|...:..|:.|..
 Worm   658 LQPPF-FSGTFPKAVNYGAIGAVIGHEITHGFDDQGSQYDKDGNLHNWWSESSLNSFDTRRRCIV 721

  Fly   540 EQYG-------RLRLNGHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSE-SLPQL- 595
            ||||       ..|:||..     .|.||||||..::.|:.||::.:.|     .|.| .||.|
 Worm   722 EQYGNYTVPKTNFRVNGKL-----TQGENIADNGGVKEAFQAYQKYVTE-----NGEEPRLPGLQ 776

  Fly   596 NLGSRRLFFLSFAQLWCNDANEQFRDKQSLF-LGTPNALRVLGALSNFRAFGRDFNCGTASRMTS 659
            ...:.::||:|:|..||....|....:|.|. ..:|...||:|.|||.:||...:.|...:.:..
 Worm   777 QYTNEQIFFVSYAHFWCGKKKEAAAMQQVLTDEHSPEVFRVIGVLSNMQAFADVYKCPRNAPVNP 841

  Fly   660 PQKC 663
            ..||
 Worm   842 DHKC 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	166/715 (23%)
nep-11	NP_494538.1	M13	181..845	CDD:341056	164/713 (23%)