Protein Alignment Nepl19 and nep-10

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_494532.2
• Gene: nep-10 / 173684
• WormBaseID: WBGene00017555
• Length: 711
• Species: Caenorhabditis elegans
• Alignment Length: 692
• Identity: 142/692 - (20%)
• Similarity: 267/692 - (38%)
• Gaps: 157/692 - (22%)

  Fly    64 EMRSYMQQDADACENFYDYSCGNWPQ---INPANDAYPRETNFVQLLLKAYSHKQQRLMEQPANV 125
            |:.:|.....|.|::||.:.||.:.:   |.....|..|.|  :..|::.:..|.:....:..|.
 Worm    88 ELHNYKDPSVDPCQDFYQHFCGKFYEHSAIGQGRMATKRST--LSKLIREFLLKNKTSTSKSENT 150

  Fly   126 ETDEVAVLRLKEFYASCLLFRQVPE--DLYRRQLQEIVAD---FGRMPVLSLPGQEWPAEEFDWL 185
                     :|:.||.|...:::.:  .:..:.|.:|.:|   .|..|||.   ::|...:|:..
 Worm   151 ---------MKQVYAKCRELQKISDLNSIPPQALLDIFSDIKKIGAWPVLD---KDWDGSKFNLN 203

  Fly   186 DTVARIKRQ-------YGFDILLLFQQSADRIYV--------GQPKQILP-------EANRKAVA 228
            :.:.::...       :.||.:.       |.||        |..|.:|.       |||...:.
 Worm   204 EMLRQLVNLGETHLGFFHFDFIA-------RPYVLIKPPLKQGVQKSVLEKVVKMILEANEIKMD 261

  Fly   229 EDIANHLERHLGVDPKVAVTTAREITEFEQKIAAIMVD-RRVGVMSKLYTPSDADYVDVSKLTQF 292
            :..:..|:.:..:..::.:.   ::....:.|..::.| ||:.....:     .:.:..||:.:|
 Worm   262 QGFSEDLDEYFELSNRIKID---KLPRTSRSIVGLLPDVRRINFRGLI-----LEMMPRSKMNRF 318

  Fly   293 VETVLDRELLANESLY------QHVPDYLMKIDELVTETPPHVLANY-VFNEL---LKHFYY--- 344
            :.|:..:.:..:..|:      .|       :|.::..|....|||| :||.:   :|...:
 Worm   319 LGTLFQKVVTYHHPLFVRDNETNH-------LDTIIRSTSNRALANYLIFNFIHSSIKFLTFGLK 376

  Fly   345 ---ERAESVVEQCVSR--VRDLFGELLDHMLFEQYEDEGTLKDIYVVWQQLQRSFRGVLQNSSAN 404
               ||.|.:|.|.:.|  :|         :......|:|..:::..:.:.::.:...:::.|.:
 Worm   377 SDRERCEKIVVQELPRPSLR---------VFMRNCVDKGNREEVAKLTETVKENVLEMIRESDS- 431

  Fly   405 WLVPETREQLLEQLNTTSLVINGYAE-----VNFTQRYEELHLKPRD-------YLHNLRTILNH 457
             ..|..::::|:::.....:| ||.:     ....:.||.|.|...|       .||.||  |.|
 Worm   432 -FTPSVKKRVLKKVEAIGAII-GYPDHFDPPGTLDKEYENLTLDASDSYYKMSQKLHQLR--LQH 492

  Fly   458 QSLRVKVKT---------QTSVTYDPVGKRVLLPVALLQPNFLWSRYYPKAVRYGSLGTLLAQQL 513
            |...:..:|         :.:..||.....:.:....|...|..|. ||:.|.....|.|:..:.
 Worm   493 QMEFLAGQTPLSPSDQVLEVNAHYDSKDNALTVLAPFLDDPFFDST-YPEYVNLIFTGFLIGHEF 556

  Fly   514 AHSLED----ASKW-DAKSFAEYSKRKSCFKEQYGRL-------RLNGHYLPESDLQAENIADNL 566
            .||::.    ...| ..:...||.||..|..:||...       ::||.|     ...|.:.|.:
 Worm   557 GHSIDPKILRRDGWYKTEDMTEYGKRAQCLIDQYDNYDDPDHGKQMNGTY-----CIGEIVGDWV 616

  Fly   567 AIQVAYHAYRRLLAELDPSFLGSE--SLPQLNLGSRRLFFLSFAQLWCNDANEQFRDKQSL--FL 627
            ...|.:.|::::........:|.|  :|.||....:.|||       |..     |..:||  .|
 Worm   617 GRDVTWRAFKKMDLSKMQKLIGFEDKNLDQLYFRIQSLFF-------CGP-----RSMKSLEQLL 669

  Fly   628 GTPN---ALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
            ..|:   ..||.|..||...|.:.|||...|.|...:||::|
 Worm   670 SDPHPTEVFRVNGIYSNMPQFAKAFNCPIGSPMNPEKKCKMF 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	138/679 (20%)
nep-10	NP_494532.2	M13	97..709	CDD:341056	138/679 (20%)