Protein Alignment Nepl19 and nep-9

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_494531.2
• Gene: nep-9 / 173683
• WormBaseID: WBGene00017554
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 703
• Identity: 147/703 - (20%)
• Similarity: 263/703 - (37%)
• Gaps: 177/703 - (25%)

  Fly    64 EMRSYMQQDADACENFYDYSCGNWPQ---INPANDAYPRETNFVQLLLKAYSHKQQRLMEQPANV 125
            |:::|......:||:||..:|.|:..   ::...|...|:.  |..|::.:..:.    |.....
 Worm    75 ELKAYSDTATKSCEDFYKATCENYKDHQALDRHRDCKKRKA--VNKLVRGFLQRD----ESTFTS 133

  Fly   126 ETDEVAVLRLKEFYASCLLFRQVPEDLYRR----QLQEIVADFGRMPVLSLPGQEWPAEEFDWLD 186
            |::..    :|..:..|       ::|.|.    .:.:.:...|..|||.   ..|....|:..|
 Worm   134 ESESA----IKLIFGKC-------DELSRNTSYLDIFKDIKKIGSWPVLE---HNWKDSMFNLDD 184

  Fly   187 TVARI--------------KRQYGFDILLLFQQSADRIYVGQ-PKQILP-------EANRKAVAE 229
            .:|::              .|:..|....:|..|.....:.| .|.||.       :.:||.:::
 Worm   185 VIAKLVKLGSTDFGLFKLELRKLAFGHFAVFVSSKQEQNIHQLEKTILGILKANGIQQDRKELSD 249

  Fly   230 DIANH--LERHLGVDPKVAVTTAREITEFEQKIAAIMVDRRVGVMSKLYTPSDADYVDVSKLT-- 290
            |:.::  .:.||              .||.|:        ...:..:||..|..:.:.:|.||
 Worm   250 DLKDYSDFKNHL--------------KEFYQE--------ETYIEYRLYAGSIVENLGISSLTTQ 292

  Fly   291 -QFVETVLD-------RELLANESLYQHVPDYLMKIDELVTETPPHVLANYVFNELLKHF---YY 344
             ....|.||       |.|:.|.||:....:.|..|   :.:||...|||:    |:.||   ..
 Worm   293 MALKSTGLDVFNHVNQRTLITNSSLFFGEENNLGMI---IQKTPKRTLANF----LIFHFIDVMT 350

  Fly   345 ERAESVVEQCVSRVRDLFGELLDHMLFEQYEDEGTLKDIYVVWQQLQRSFRGVLQNS---SANWL 406
            ....:..:.|...:.||.......:|...:.:|....|:..:.|.|:.....::.||   :...|
 Worm   351 TDLANATKACKETLIDLLPRASIQVLSRNFVNEDAQDDMVKMAQDLKTKITEMIDNSPFFTKFHL 415

  Fly   407 VPETREQ--LLEQLNTTSLVINGYAEVNFTQRYEELHLKPRDYLHNLRTILNHQSLRVKVKTQTS 469
            |.:..||  |::::....:|.. |.:....:.:|.|:|.|.|.::  |||   |.|| :::::..
 Worm   416 VFDAEEQKKLIQKVKAIGIVTE-YPQEVLDRDFERLNLTPSDSIY--RTI---QKLR-RLRSEQL 473

  Fly   470 VTY-----DPVGKRV---------------LLPVALLQPNFLWSRYYPKAVRYGSLGTLLAQQLA 514
            :.:     ||...||               ..|: :..|.|..|  ||..|....:|.:|.::|.
 Worm   474 IEHLGGDLDPTDTRVWGSAHYDQTTNNLTIFAPI-IDGPYFDTS--YPNYVNQFLMGFILGRELG 535

  Fly   515 HSLE----------DASKW----DAKSFAEYSKRKSCFKEQY------------GRLRLNGHYLP 553
            .||:          ....|    ..|.|.|:.|   |:.|:|            |..::.|.|
 Worm   536 RSLDSVRIRKDEKGQTENWLKPESLKRFDEHLK---CWAEKYDKSADPLKSESKGIRQIEGRY-- 595

  Fly   554 ESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQLNLGSRRLFFLSFAQLWCNDANE- 617
               :|.|..||.:..:.::.|:.:|..:.:...   |:...:.|  ||:||...|..:|...:.
 Worm   596 ---IQNEMFADFIGHEASWRAFMKLDVKNEEVL---ETFKVIKL--RRMFFNVQALYFCRPPSGS 652

  Fly   618 ----QFRDKQSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
                .:::....:     :.||.||..|...|...|.|.:...|....||.:|
 Worm   653 TDWLSYQEHHQHY-----SFRVNGAFKNMPQFALAFECASDDDMNPQNKCSMF 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	143/690 (21%)
nep-9	NP_494531.2	GluZincin	87..698	CDD:472708	143/687 (21%)