Protein Alignment Nepl19 and Nep3

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: XP_317711.2
• Gene: Nep3 / 1278166
• VectorBaseID: AGAMI1_011685
• Length: 789
• Species: Anopheles gambiae
• Alignment Length: 711
• Identity: 162/711 - (22%)
• Similarity: 294/711 - (41%)
• Gaps: 145/711 - (20%)

  Fly    62 SAEMRSYMQQDADACENFYDYSCGNWPQINPANDA------YPRETNFVQLLLKAYSHKQQRLME 120
            ::|:...:....|.|::||.:||..|.:.||..:.      :.:.....||:||       ..:|
Mosquito   112 ASEILHSIDWSVDPCDDFYAFSCNQWIRNNPIPEGKSMWGLFGKLEQQNQLVLK-------NALE 169

  Fly   121 QPANVETDEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLS----LPGQEWPAEE 181
            :|. .|....|..:.|.:|.|||...:..|.|....||:::...|...|.:    ...|.|..:.
Mosquito   170 RPL-AEFKSKAEKKAKLYYQSCLDEDETMEKLGAEPLQKLLRQIGGWNVTANASGFDVQRWSLQR 233

  Fly   182 FDWLDTVARIKRQYGFDILLLFQQSADR-------IYVGQPKQILPE----ANRKAVAEDIANHL 235
                 |:..::.:|....|..:....|.       |.:.|....||.    .|:.|.|:.:..:|
Mosquito   234 -----TLQTLQIRYNMGGLFGWAVGEDDRNSSKHIIQIDQGGLTLPSRDNYLNKTANAKILTAYL 293

  Fly   236 ERH------LGVDPKVAVTTAREITEFEQKIAAIMV--DRRVGVMSKLYTP-------SDADYVD 285
            |..      ||.|...|.....|:.|||.::|.|..  |.|.. ...||.|       ..|.:::
Mosquito   294 EYMTKVSVLLGADETDARRQMLEVIEFETRLANITTPQDMRRD-EETLYHPMTLAMLQEKAPFIN 357

  Fly   286 VSKLTQFVETVLDRELLANESLYQHVPDYLMKIDELV-----TETPPHVLANYV----------- 334
            ..:..:....::.|::...|.:..:.|:||.|::.|:     |:....:|.||:
Mosquito   358 WQEHFEEAFRLVRRKITEKERVVVYAPEYLEKLNILMKEYTSTDEKKIILNNYLVWQTVRTLTAC 422

  Fly   335 ----FNELLKHFY-----YERAESVVEQCVSRVRDLFGELLDHMLFEQYEDEGTLKDIY------ 384
                |.:..|...     .:..|.:...|||...::.|..:..|.         ::|::
Mosquito   423 LSKAFRDAYKGLRKALMGSDGGEELWRYCVSDTSNVLGFAVGAMF---------VRDVFHGDSKP 478

  Fly   385 ---VVWQQLQRSFRGVLQNSSANWLVPETREQLLEQLNTTSLVINGYAEV-----NFTQRYEELH 441
               .:..|::.:|:...:|  ..|:..|||...:|:.:..|.:| |:.:.     ...::|::|:
Mosquito   479 QAEEMINQVRDAFKENFKN--LGWMDAETRRLAVEKADAISDMI-GFPDYILYPEELDRKYQDLN 540

  Fly   442 LKPRDYLHNLRTILNHQSLRVKV--------KTQTSVT-------YDPVGKRVLLPVALLQPNFL 491
            :.|:.|..| ....|..||:..:        ||:..:|       |.|...:::.|..:|| |..
Mosquito   541 IDPKTYFDN-NINYNIYSLKKNLEKLDQPVNKTKWGMTPPTVNAYYTPTKNQIVFPAGILQ-NPF 603

  Fly   492 WSRYYPKAVRYGSLGTLLAQQLAHSLEDASK-----------WDAKSFAEYSKRKSCFKEQYGRL 545
            :.....|::.||::|.::..:|.|:.:|..:           |:.::...:..:..||.:||...
Mosquito   604 FDIKNSKSLNYGAMGVVMGHELTHAFDDQGREYDKYGNLHQWWNNQTIERFKNQTECFNQQYSAY 668

  Fly   546 RLNGHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSES--LPQLNLGSRRLFFLSFA 608
            |:||..:.......||||||..::.|:|||   :.....|:..:::  ||.:|:..|:|||:|||
Mosquito   669 RINGKTINGKQTMGENIADNGGLKAAFHAY---INNEKNSYTDTDTLPLPGVNMTHRQLFFVSFA 730

  Fly   609 QLWCNDANEQF------RDKQSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKC 663
            |:||:...::.      :|..|     |...||:|.|||.:.|...|:|...:.|...:||
Mosquito   731 QVWCSAVTDETTTLQIEKDSHS-----PPKYRVIGPLSNLKEFSDTFHCPLGTGMNPIEKC 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	161/700 (23%)
Nep3	XP_317711.2	None