Protein Alignment Nepl19 and Nep4

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: XP_061501026.1
• Gene: Nep4 / 1273777
• VectorBaseID: AGAMI1_013990
• Length: 1007
• Species: Anopheles gambiae
• Alignment Length: 826
• Identity: 212/826 - (25%)
• Similarity: 342/826 - (41%)
• Gaps: 217/826 - (26%)

  Fly    30 QP--AIDLRIQAREQL------ISQSNDSAYVQRLMRLSKSAEMRSYMQQDADACENFYDYSCGN 86
            ||  |.:..::..|||      :...||.......:|.::.|.|:.||..|||.|::||.|:|||
Mosquito   210 QPSTATEKAVERSEQLPRVRRSVGWMNDDRSSPESVRAAQVAIMKQYMDPDADPCDDFYQYACGN 274

  Fly    87 WPQINP------ANDAYPRETNFVQLLLK----------------AYS----------------- 112
            |.::||      |.|.:......:.|:||                |.|
Mosquito   275 WDRVNPIPKDKAALDTFELLRESLDLVLKQLLLEGEPAGLLDVENALSTVRSQPDGTKKSTSTTT 339

  Fly   113 ---------------------HK-----------------QQRLMEQPANVE---------TDEV 130
                                 |:                 |.:|:.:.|.|:         .::.
Mosquito   340 TAASAGWPTTTVTGGPAQQQLHRVRKRGRAENRNRSGRAVQNKLIIRSAQVKRVRRKRELLINDD 404

  Fly   131 AVLRLKEFYASCLLFRQVPEDLYRR---QLQEIVADFGRMPVLSLPGQEWPAEEFDWLDTVARIK 192
            |.::.:..:.||:.:    |.:.||   .|:.::...|..|||.  ...|....||||:..|.::
Mosquito   405 AEMKARHLFVSCMNY----ELIERRGLEPLRTLLHSLGGWPVLE--PHTWDESSFDWLNLTAALR 463

  Fly   193 RQYGFDILLL----------------FQQSA----DRIYVGQP--KQILPEANRKAVAEDIANHL 235
            | |..|:|::                |.|::    .|.|..||  ::.| ||.|:.:.|.|.
Mosquito   464 R-YNNDVLIVEWVGPDIKNSDENIVQFDQTSLGLPTRDYYLQPGNRKYL-EAYRQFMLEVIG--- 523

  Fly   236 ERHLGVDPKVAVTTAREITEFEQKIAAI--MVDRRVGVMSKLYTPSDADYV--DVSKL--TQFVE 294
              .|.|....|.....|:.|||.::|.|  ..:.|..| |.||.....|.:  :|.::  |.::.
Mosquito   524 --LLDVPADTARQATDEMIEFETQLANITSTPEERNNV-STLYRKLMLDQLQEEVPQINWTHYLT 585

  Fly   295 TVLDRELLANESLYQHVPDYLMKIDELVTETPPHVLANYVFNELLKH------------------ 341
            .|.:|.:..:..:......|:..:.||:.:|.|.::|||:....::|
Mosquito   586 IVTERPVNGSSFVVMFAMSYMRDLVELIDQTEPRIVANYLLWRFVRHRINNLDDRFLGAKQRFSN 650

  Fly   342 --FYYERAESVVEQCVSRVRDLFGELLDHMLFEQYEDEGTLKDIYVVWQQLQRSFRGVLQNSSAN 404
              |..||.....:.||::|....|..:..|...:|.||.:.:|...:..:||.:||.:|  ....
Mosquito   651 ALFGRERNPPRWKNCVTQVNANMGMAVGAMFVRRYFDENSKRDTLTMTHELQDAFREIL--GRTG 713

  Fly   405 WLVPETREQLLEQLNTTSLVINGYAEV-----NFTQRYEELHLKPRDYLHNLRTILNHQSLRVKV 464
            |:...||:...:::|..||.| ||.:.     ..:.||..|.:.|..|..|...:|:|  :|
Mosquito   714 WIDMATRQLAEQKVNAMSLRI-GYPDFILDPEQLSARYATLEIHPDRYFENTLNVLSH--IR--- 772

  Fly   465 KTQTSVTYDPVGK-------------------RVLLPVALLQPNFLWSRYYPKAVRYGSLGTLLA 510
            :|.......||.|                   :::.|..:|||.| :.|:.|||:.||.:|.::.
Mosquito   773 RTDQEKLGQPVNKTAWHTAPAVVNAYYSRNKNQIMFPAGILQPPF-YHRHLPKAINYGGIGVVIG 836

  Fly   511 QQLAHSLEDASK-----------WDAKSFAEYSKRKSCFKEQYGRLR-------LNGHYLPESDL 557
            .:|.|..:|..:           |..::..|:.:|.:|..|||||.|       |:|     .:.
Mosquito   837 HELTHGFDDKGRLFDRDGNLYRWWSDRAIEEFHERAACLVEQYGRYRIAEVDVQLDG-----ENT 896

  Fly   558 QAENIADNLAIQVAYHAYRR-LLAELDPSFLGSESLPQLNLGSRRLFFLSFAQLWCNDAN-EQFR 620
            |.||||||..|:.|:.||.: |.|:.|...|.:|:||.||:...:||||:|||:||.... |..|
Mosquito   897 QGENIADNGGIKQAFLAYSKWLAAQTDRRVLEAETLPGLNVTRTQLFFLNFAQIWCGAMRPEATR 961

  Fly   621 DKQSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
            :|....:.:|...||:|.|||...|.|:::|...|.|..|.||.::
Mosquito   962 NKLKTAVHSPGRFRVIGTLSNSEDFAREYHCPVGSTMNPPGKCSVW 1007

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	197/771 (26%)
Nep4	XP_061501026.1	None