Protein Alignment Nepl19 and kel

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: XP_068070210.1
• Gene: kel / 101882278
• ZFINID: ZDB-GENE-110411-118
• Length: 793
• Species: Danio rerio
• Alignment Length: 665
• Identity: 154/665 - (23%)
• Similarity: 246/665 - (36%)
• Gaps: 168/665 - (25%)

  Fly   108 LKAYSHKQ-------QRLMEQPANVETDEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFG 165
            ||.:..:|       :.::|.|....:...|..:.|.|:.||:          ..:.:|   ..|
Zfish   188 LKTFPDRQTALLTAIKEILEAPDEAVSMGAAEQKAKNFFKSCM----------NAESRE---KMG 239

  Fly   166 RMPVLSLPGQ--EWPA----EEFDWLDTVARIKRQYG-FDILLLFQQSADRIYVG-QPKQILPEA 222
            ..|.|:|..|  .|..    .:.|:..|:|.:..||. |...        .:||| :|.:....:
Zfish   240 SEPFLTLLQQLGGWAVSGVWNQTDFNSTLALLMGQYSTFPFF--------NVYVGPEPSEEQSAS 296

  Fly   223 NRKAVAEDIANHLERHLGVDPKV--AVTTAREITEFEQKIAAIMVDRRVGVMSKLYTPSDADYVD 285
            ||..:..| ..|.:..:..:.|.  |....|.:..|.......:|  .:||.|...|.....:|.
Zfish   297 NRHYIQID-EPHFQFPIEWNSKTQKAKANTRYLRPFYSACGQYLV--LLGVPSDRTTQHCGLFVS 358

  Fly   286 VSKLTQFVETV-----LDRELLANESLYQHV------------------PDYLMKIDELVTETPP 327
            :| .|..|.|.     |.::||...:..|.:                  |..:.|.|.::....|
Zfish   359 LS-TTLAVATFPLPYRLSQKLLYRRTTIQELQTLAPAVDWLACLQATFQPLLISKSDIVLVHNLP 422

  Fly   328 HV---------------------LANYVFNELL---------KHFYYERAESVVE---------- 352
            ::                     |..|:...||         :.|...|..|:..
Zfish   423 YIIHMSKTIHLWQVQHELMGTGPLNTYMIFSLLQTLIPALDSRFFQIMRNYSIATGDTQEMPHWW 487

  Fly   353 QCVSRVRDLFGELLDHMLFE---QYEDEGTLKDIYVVWQQLQRSFRGVLQNSSANWLVPETREQL 414
            :||.:....|..||.|.:.|   |.|.|..::|:|   ..|::..      :..:|...:..:.:
Zfish   488 RCVQQTERGFDTLLSHAIREKHAQKEAEELIQDVY---SSLKKKL------TDLSWRDEKESDFI 543

  Fly   415 LEQLNTTSLVIN------GYAEVNFTQRYEELHLKPRDYLHN-LRTILNHQSLRVK---VKTQT- 468
            |.::|:.:..|:      .|.|:|  ..||::.|...|:..| |:.:|..|..|.:   :.|||
Zfish   544 LNKINSLNPRISTNTNNLSYTELN--HLYEKVILNEEDFFSNYLQILLLEQKSRARLLSLGTQTE 606

  Fly   469 --SVTYDPVGKRVLLPVALLQPNFLWSRYYPKAVRYGSLGTLLAQQLAHSL-----EDASKWDAK 526
              |:|....|..:::||.:....|..|. ||:|:.||:||:|:|:.|.|.|     ..|...:.:
Zfish   607 GLSMTPFISGNDIIVPVGMFVSPFFHSS-YPRALNYGTLGSLMAKDLLHLLLPDIYTKAKNPETE 670

  Fly   527 SFAEYSKRKSCFK-EQYGRLRLNGHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSE 590
            |...:|...|..| ..:|    :..|||.|. |.|......|:|||..||:.....    :|...
Zfish   671 SLCVWSHYLSVTKGPGWG----DAFYLPSSK-QQEVWVQYSALQVALDAYKMSFKR----YLADS 726

  Fly   591 SLPQLNLGSRRLFFLSFAQLWCN-DANEQFRDKQSLFLGTPNALRVLGALSNFRAFGRDFNCGTA 654
            |||  ......||..||.::.|: ||..:|...:..||.|     ||  .||.....:...|
Zfish   727 SLP--GFSYVHLFLSSFTKVTCDTDAYREFMPLEPSFLVT-----VL--CSNSGLCPKPLTC--- 779

  Fly   655 SRMTSPQK-----CQ 664
              |..||.     ||
Zfish   780 --MNKPQSFPAEMCQ 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	152/663 (23%)
kel	XP_068070210.1	GluZincin	133..>654	CDD:472708	109/502 (22%)
		GluZincin	617..>755	CDD:472708	45/149 (30%)