Protein Alignment Nepl19 and ece1

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: XP_031762312.1
• Gene: ece1 / 100485607
• XenbaseID: XB-GENE-1014218
• Length: 782
• Species: Xenopus tropicalis
• Alignment Length: 693
• Identity: 169/693 - (24%)
• Similarity: 291/693 - (41%)
• Gaps: 119/693 - (17%)

  Fly    62 SAEMRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQ---QRLMEQPA 123
            |:.:|| :.:.||.|::||.||||.|.:.||..|.:.|...|.:|    :.|.|   :.|:|. :
 Frog   121 SSILRS-LDRSADPCQDFYQYSCGGWIKGNPVPDGHSRWGTFNEL----WEHNQATMKHLLEN-S 179

  Fly   124 NVETDEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEFDWLDTV 188
            .:||:..|..:.:.::.:|:...:: |:|..:.||:::...|...:..    .|..:.|.  :|:
 Frog   180 TIETNSTAERKAQRYFQACMNETKI-EELGAKPLQDLIQKLGGWAITG----PWDRDNFQ--ETL 237

  Fly   189 ARIKRQYGFDILLLFQQSADR-------IYVGQPKQILPE----ANRKAVAEDIANHLE--RHLG 240
            ..:...|..........|||.       |.:.|....||.    .|:....:.:..:|.  ..||
 Frog   238 QLVTAHYRTSPFFSVFVSADSKNSNSNVIQIDQSGLGLPSREFYLNKTENEKVLTGYLNFMIQLG 302

  Fly   241 VDPKVAVTTAR----EITEFEQKIAAIMVDR-----RVGVMSKLYTPSDADYVDVSKLTQFVETV 296
            |....|..:.|    ||.:||..:|.|.:.:     ...:..|:......|.|.......|::||
 Frog   303 VLLGGAENSTREQMQEILDFETTLANITIPQEKRRDEEQIYHKMAAGELKDLVPAVDWMPFLQTV 367

  Fly   297 LDRELLANES--LYQHVPDYLMKIDELVTETPPHVLANYVFNELLK---HFYYERAESVVEQ--- 353
            . ..:..|||  :..:..:||:.:..|:..|...:|.||:...|::   .|..:|.:...|:
 Frog   368 F-YPVAINESEPVVVYAKEYLVAVSGLINSTDKRILNNYMMWNLVRKASSFLDQRFQDAEEKLME 431

  Fly   354 ---------------CVSRVRDLFGELLDHMLFE-QYEDEGTLKDIYVVWQQLQRSFRGVLQNSS 402
                           |:|...:..|..|..|..: .:.:...|:.:.:: ::::.:|...|  |:
 Frog   432 VMYGTKKTCLPRWKFCISDTDNNLGFALGAMFVKATFAENSKLQALKMI-KEIKAAFEENL--ST 493

  Fly   403 ANWLVPETREQLLEQLNTTSLVINGYAEVNFTQRYEELHLKPRDY-------------LHNLRTI 454
            ..|:..|||....|:......:| ||.  ||....:||.....||             .:|....
 Frog   494 LTWMDDETRRAAREKAEAIYDMI-GYP--NFIMDPKELDKVFNDYNVTSDFYFENGMRFYNFSAR 555

  Fly   455 LNHQSLR-VKVKTQTSVT-------YDPVGKRVLLPVALLQPNFLWSRYYPKAVRYGSLGTLLAQ 511
            :....|| ...|.|.|:|       |.|....::.|..:||..| ::...|.|:.:|.:|.::..
 Frog   556 VTADQLRKAPSKDQWSMTPPTVNAYYSPTKNEIVFPAGILQAPF-YTSSSPTALNFGGIGVVMGH 619

  Fly   512 QLAHSLEDASK-----------WDAKSFAEYSKRKSCFKEQYGRLRLNGHYLPESDLQAENIADN 565
            :|.|:.:|..:           |...|...:.|:..|..||||...:||..:.......||||||
 Frog   620 ELTHAFDDQGREYDKDGNLRPWWKNASVEAFKKQTECITEQYGNYTVNGEPVNGRQTLGENIADN 684

  Fly   566 LAIQVAYHAYRRLLAELDPSFLGSES-LPQLNLGSRRLFFLSFAQLWCNDANEQFRDKQSLFLG- 628
            ..::.||.||:..:.:     .|:|. ||.|.|.:.:|||:.|||:||:     .|..:|...|
 Frog   685 GGLKAAYRAYKNWVRK-----NGAEQLLPSLGLSNDQLFFVGFAQVWCS-----VRTSESSHEGL 739

  Fly   629 -----TPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
                 :|:..||:|::||.:.|...|.|...|.|....||:::
 Frog   740 ITDPHSPSRFRVIGSVSNSQEFAEHFRCPPGSPMNPRNKCEVW 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	165/678 (24%)
ece1	XP_031762312.1	M13	131..780	CDD:341056	165/678 (24%)