Protein Alignment Nepl19 and ecel1

DIOPT Version :10

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_001429584.1
• Gene: ecel1 / 100332538
• ZFINID: ZDB-GENE-130530-692
• Length: 808
• Species: Danio rerio
• Alignment Length: 738
• Identity: 161/738 - (21%)
• Similarity: 292/738 - (39%)
• Gaps: 161/738 - (21%)

  Fly    46 QSNDSAYVQRLMRLSKSAEMRSYMQQDAD----ACENFYDYSCGNWPQINPANDAYPRET---NF 103
            :|.||...|..::.........::|.:.|    .|.:||.::||.|.:    ....|.:.   ..
Zfish   115 ESQDSQCRQDCVKRRSLLRAARFVQGNIDPSVQPCHDFYSFACGGWLR----RHGIPEDKLSYGI 175

  Fly   104 VQLLLKAYSHKQQRLMEQPANVETDEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMP 168
            :..:.:....|.|||::.|......|.|..::||||.||:..::: :.|....:.|::...|...
Zfish   176 ITAIGEQNQDKLQRLLQAPVQRRELESAERKVKEFYRSCINIKEI-DRLGAGPMTEVIDSCGGWD 239

  Fly   169 VLSLP--GQEWPAEEF----DWLDTVARIKRQYGFDILLLFQQSAD-------RIYVGQPKQILP 220
            :...|  |..|.:...    |:.:.:.:.:..|...:......|.|       .|.:.|....||
Zfish   240 LSGAPPGGAGWDSGSAPIRPDFNEMLYKTQGVYSTSVFFSLTVSVDDKNSSRNAIRIDQEGLTLP 304

  Fly   221 E---------------ANRKAVAEDIANHLERHLGVDPKVAVTTAREITEFEQKIAAIMV----D 266
            |               |:.||:.|.:.:.|..|      .|...:|||.:.|.|:|.|.|    |
Zfish   305 ERTLYLGQDEDSVKILASYKALMERLLSMLGAH------NATLKSREILDLETKLANITVSEYED 363

  Fly   267 RRVGVMSKLYTPSDADYVDVSKLTQFV-----ETVLDRELLAN----ESLYQHVPDYLMKIDELV 322
            :|..: |.:|     :.:.:.:|.:..     :.:|||....|    |.:.....||:..:.:::
Zfish   364 QRKDI-SSMY-----NRITLKQLQKMAPSFHWKRLLDRIFNDNFSEEEEIVVLATDYMQTVSDII 422

  Fly   323 TETPPHVLANYVFNELLK--------------HFYYERAESVVEQ------CVSRVRDLFGELLD 367
            ..|...||.||:...::.              |.:....:...:|      |:::....||..|.
Zfish   423 KTTSKRVLHNYMLWRMVAALSEHLSTAFRSTIHEFSREIDGTEQQLDLERLCLTQANKHFGMALG 487

  Fly   368 HMLFEQYEDEGTLKDIYVVWQQLQRSFRGVLQNSSANWLVPETREQLLEQLNTTSLVINGYAEVN 432
            .:..:|:....:...:..:.:.::.|....||  ..:|:..||::....:|. ..:|:.|
Zfish   488 ALFVQQHFSSSSRAKVQELVEDIKHSLDVRLQ--ELDWMDEETKDAARGKLQ-HMMVMTG----- 544

  Fly   433 FTQRYEELHLKP----RDYLHNL------RTILNHQSLRVKVKTQ-----------------TSV 470
                |.:..|||    .:|..::      :.|||.....:|:..:                 .:.
Zfish   545 ----YPDFLLKPELIDEEYAFDVNEKTYFKNILNSIKYNIKLSIKKIHKEVDKTTWLLPPQALNA 605

  Fly   471 TYDPVGKRVLLPVALLQPNFLWSRYYPKAVRYGSLGTLLAQQLAHSLED-----------ASKWD 524
            .|.|...:::.|..:|||. |:...:|:::.||.:|.::..:|.|..:|           ...|.
Zfish   606 YYLPNKNQMVFPAGILQPT-LYDPEFPQSLNYGGIGAIIGHELTHGYDDWGGQYDRYGNLKQWWT 669

  Fly   525 AKSFAEYSKRKSCFKEQYGRL-----RLNGHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDP 584
            .:|:.::.|:..|..:.|...     |:||..     ...|||||...::::||||::.:.|..|
Zfish   670 EESYRKFQKKTECIVKLYDNFTVYNQRVNGRL-----TLGENIADLGGLKLSYHAYQKWVREHGP 729

  Fly   585 SFLGSESLPQLNLGSRRLFFLSFAQLWCNDANEQFRDKQSLFL------GTPNALRVLGALSNFR 643
                ...||.|.....:|||::|||.||     ..|..||::|      ..|...||:|::|.|.
Zfish   730 ----ERPLPGLKHTHEQLFFIAFAQNWC-----MKRRSQSIYLQLLTDKHAPEHYRVIGSVSQFE 785

  Fly   644 AFGRDFNCGTASRMTSPQKCQLF 666
            .|||.|:|...|.|....||.::
Zfish   786 EFGRVFHCPRGSPMNPVNKCSVW 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	M13	73..664	CDD:341056	155/707 (22%)
ecel1	NP_001429584.1	None