Protein Alignment Nepl19 and mmel1

DIOPT Version :9

• Sequence 1: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: XP_012821551.1
• Gene: mmel1 / 100145721
• XenbaseID: XB-GENE-991673
• Length: 765
• Species: Xenopus tropicalis
• Alignment Length: 768
• Identity: 163/768 - (21%)
• Similarity: 283/768 - (36%)
• Gaps: 243/768 - (31%)

  Fly    59 LSKSAEMRSYMQQDADACENFYDYSCGNW------PQINPANDAYPRETNFVQLLLKAYSHKQQR 117
            ::.:|.:...|....:.|.:||.|:||.|      |:.:.....:....:.::::||.
 Frog    81 VTAAARIIQNMDPTIEPCTDFYQYACGGWLNKHVIPETSSRYSIFDILRDEMEIILKG------- 138

  Fly   118 LMEQPANVETDEVAVLRLKEFYASCLLFRQVPEDLYRRQ----LQEIVADFGRMPVLSLPGQEWP 178
            |:|.|...:.|  |..:.|..|.||:     .|.|..::    |.|::...|          |||
 Frog   139 LLEMPDQEDRD--AFKKAKILYKSCM-----NESLIEQRDSLPLLELLTTVG----------EWP 186

  Fly   179 AEEFDWLDT----------VARIKRQYGFDILL-LFQQSADR------IYVGQPKQILPEAN--- 223
            ....||..|          ::.:..::...:|: :|..:.||      ||:.||...:|..:
 Frog   187 VASTDWNGTKESNWSLEEKLSLLNYKFNKRVLVDIFVWNDDRESSKHIIYIDQPSLGMPSRDYYF 251

  Fly   224 --------RKA-----------VAED---------IANHLERHLGVDPKVAVTTA-----REIT- 254
                    |:|           |.||         :...:.|.:.::..:|..||     .::|
 Frog   252 NKGNYQRIREAYLQFMITIARMVREDRNLTRDDSLVQEEMTRVMDLETDIARATAPSEERNDVTL 316

  Fly   255 --------EFEQKIAAIMVDRRVGVMSKLYTPSDADYVDVSKLTQFVETVLDR---ELLANESLY 308
                    ||:||.|                      :|....|.|::.|:..   :|.|.|.:.
 Frog   317 LYNKMTLLEFQQKFA----------------------LDDFNWTSFIQGVMSSVNIQLQAEEEVV 359

  Fly   309 QHVPDYLMKIDELVTETPPHVLANYV--------FNELLKHFYYERA------------ESVVEQ 353
            .:...||.::..:::......|.|||        .:.|.:.:...||            |:...:
 Frog   360 VYGAPYLHQLKNILSNYSASTLQNYVVWRMVIDRVSSLSRRYKDARASYRKALYGTTLEEARWRE 424

  Fly   354 CVS--------------------------------RVRDLFGELLDHMLFEQYEDEGTLKDIYVV 386
            |||                                :||:.|.|.||.:   |:.|| |.||
 Frog   425 CVSYVNSNMENAVGAMYVKETFAGESKRMISDLINKVREAFIETLDEL---QWMDE-TSKD---- 481

  Fly   387 WQQLQRSFRGVLQNSSANWLVPETREQLL---EQLNTTSLVINGYAEVNFTQRYEELHLKPRDYL 448
                                  :.||:.|   ||:.....::....: ...|....|:.....|.
 Frog   482 ----------------------KAREKALSIKEQIGYPDYILEDQND-KLDQETAALNFSEYQYF 523

  Fly   449 HNLRTILNHQSLRVKVKTQTSVT--------------YDPVGKRVLLPVALLQPNFLWSRYYPKA 499
            .|:..|||..:.:...|.:..|.              |.|...:::.|..:|||.| ::::.|:|
 Frog   524 ENILEILNSGAQKSLKKLREPVDQDAWIIGAAVADAFYSPNRNQIVFPAGILQPPF-FNKHQPQA 587

  Fly   500 VRYGSLGTLLAQQLAHSLEDASK-----------WDAKSFAEYSKRKSCFKEQYGRLR---LNGH 550
            :.:|.:|.::..::.|..:|..:           |...|...:..:..|...|||...   ..|.
 Frog   588 LNFGGIGMVIGHEITHGFDDNGRNFDKDGNMFDWWSNFSAMHFKDQSRCMVYQYGNYTWELAGGQ 652

  Fly   551 YLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSE-SLPQLNLGSRRLFFLSFAQLWCND 614
            .:.......||||||..::.||.||.:.:..     .|.| .||.|:|..::||||:|||:||..
 Frog   653 NVSGIITLGENIADNGGVRQAYKAYLKWVER-----HGKEPKLPGLDLTYKQLFFLNFAQVWCGS 712

  Fly   615 ANEQF-RDKQSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666
            ...:: |......:.:|...||:|:|.||.||..:|||...::|...:||:::
 Frog   713 YRPEYARHSIKTDVHSPFKYRVMGSLQNFEAFAEEFNCKKGTKMHPVEKCRVW 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	159/749 (21%)
		M13	73..664	CDD:189000	160/750 (21%)
mmel1	XP_012821551.1	M13	95..763	CDD:341056	160/750 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110