Protein Alignment Nepl18 and Nepl21

DIOPT Version :9

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Alignment Length: 705
• Identity: 250/705 - (35%)
• Similarity: 394/705 - (55%)
• Gaps: 35/705 - (4%)

  Fly     5 RVLWLCLLVAIVPAMAKPSDAGDPFADDLTSD--YAKKIIVQAKVAEMKTMMKPEVSPCDDFYTH 67
            ::|.:|:...::.||...:...:   :||..|  |.|:::.|||.||:::.|..:..||:|||..
  Fly    11 QLLCICIAGHVLSAMVAAAPTSE---EDLKQDTPYMKELLRQAKTAEIESFMDQKADPCNDFYAF 72

  Fly    68 ACGNWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLLR----ANDLQSELEKKMQRFYMSCNLVH 128
            :|||:.|.|.|..:..|.|..|:.::||.:|::.::|.    ::|...::  |::.||.||..:.
  Fly    73 SCGNYKRINSALSMQVVTTGVFETLTKGLNRKILKMLNTPHDSHDTPEDI--KVKHFYESCLQIK 135

  Fly   129 RDDVHYKLALENVIREYGTLPALVGAQWNSSDFSWWRTVAQIQHKYGKQIIIGLEIMHDIRNTSV 193
            ..:..|...|:.:|.|:||:|.|.|:.|...||.|..|.|::.::||...|.|:|:..|:.:.:.
  Fly   136 ELNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFDWLNTTARMAYRYGITPIFGIEVNKDLASNTR 200

  Fly   194 NRVYISQPDFKT------INTRLTNLMEEVRTSMD--LQQYFGLSSSVAKHTAEQLTELERTFSS 250
            ||:|:.|.||..      ::.......::.|.::.  ||:|.|:...:||.||::|.:.|...:.
  Fly   201 NRIYLGQQDFPLEARSMYVDDATAVYRQKYRNNIQRILQRYLGVKMDLAKKTAKELIDFEVDLAQ 265

  Fly   251 G---GSGAATLQESLSLYTVADLQEKYSDHLNFTEFLGLILGEENIPKSLYIYDEEYLDKALLTM 312
            |   .|....:.|...|.||.::|.:||..|:....|.:.:| |.|...:|.|:..|....:..:
  Fly   266 GLVDESEGLDVGELTQLLTVDEIQRRYSPTLDIDRLLFVSMG-ERISDQIYEYNNRYQQNLVEVI 329

  Fly   313 RSTPLATQANYVLWKLLEDFL--VDAQPKDMVKWCTESTKKYFGKLAEHAVYKRYRNPDVESEVH 375
            :.||..|.|||:.::|:.:|:  ....|:..:|.|.:.|||||.|..::..|:||.|.....|:.
  Fly   330 KRTPKRTVANYIFFRLIWEFVETPSDSPEKQMKACVDLTKKYFAKNLDNMFYRRYNNEKSSREID 394

  Fly   376 KIWDQIKGIFRQRLLGD-KLDWISNATRTLAIEKLERMHLNINSYDEENFENVYGEVFIDRLNYV 439
            .:|.|:|..|.:.|... .|:||...||.||:.||:.|.|.:|:|.::||...:.|:.:...:||
  Fly   395 NMWRQLKSTFNETLRSSPALNWIERPTRNLAMAKLQAMTLEVNNYADDNFTEEFAELNLQSDDYV 459

  Fly   440 SNVQ--QLLIAKGIRFVARINQPADSVDATELLGFTPAYNIQENNITIPVALLQPRYFWGDQYPE 502
            .||:  .||.||.:|  ..:::||...:|...|.:|||..:.||.|.:|||||||.|.|.|.||.
  Fly   460 ENVRYTSLLGAKQMR--EMLHKPAKPFEAGSQLSYTPANILIENTIKVPVALLQPFYIWSDVYPN 522

  Fly   503 ALKYATLGYLLAHEMLHGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEYQYGGSKL 567
            |:.:.||..|:.||::|||||.||::|..||...|||.||...|.:||.||..||..|.|.|.:|
  Fly   523 AIMFGTLASLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYDGIQL 587

  Fly   568 PESKDQSENIADSGGLKLAYAAYELWLGQQ-----SEEVLQRETMEGLPFNSRQLFFLGYAQLLC 627
            .||..|||||||:||::|||.||..|...|     ..:.:.:||:..|.:.::||||:.:||..|
  Fly   588 KESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWC 652

  Fly   628 DDVQFLFQPWVSQSDRHAPSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682
            :|.....:.....:|:|.|.::||||.||||:||...|||...:.|:|..||.:|
  Fly   653 NDAHPSVKALQVSTDQHMPGRFRVIGSLSNFEEFSKEFNCPAGSAMNPSEKCILY 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	235/652 (36%)
		M13	58..679	CDD:189000	232/645 (36%)
Nepl21	NP_651646.2	PepO	57..707	CDD:226118	235/654 (36%)
		M13	63..704	CDD:189000	232/645 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451240
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	1	1.000	-	-		FOG0007609
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950