Protein Alignment Nepl18 and Nepl20

DIOPT Version :9

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Alignment Length: 714
• Identity: 258/714 - (36%)
• Similarity: 404/714 - (56%)
• Gaps: 47/714 - (6%)

  Fly     2 MTSRV--LWLCLLVAIVPAMAKPSDAGDPFADDLTSD--YAKKIIVQAKVAEMKTMMKPEVSPCD 62
            ||.::  :|:...|..|..:|.|:.     .|.|..|  |.|:::.|||.||:::.|..:|.||.
  Fly     1 MTMKLFCIWIASHVLSVLVLAAPTS-----EDVLNQDTPYMKELMRQAKAAEIESFMNQKVDPCK 60

  Fly    63 DFYTHACGNWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLLR----ANDLQSELEKKMQRFYMS 123
            |||..:|||:.|.|.|..:..:.|..|:.::||.:|::.::|.    ::|...:::.|  .||.|
  Fly    61 DFYAFSCGNYKRINSALNMRVLTTGVFETLTKGLNRKILKMLNTPHDSHDTPEDIQVK--HFYES 123

  Fly   124 CNLVHRDDVHYKLALENVIREYGTLPALVGAQWNSSDFSWWRTVAQIQHKYGKQIIIGLEIMHDI 188
            |..:...:..|...|:.:|.|:||:|.|.|:.|...||.|..|.|::.|:||...|||:.:..|.
  Fly   124 CLQIKELNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFDWLNTTARMAHRYGIMSIIGVGVATDF 188

  Fly   189 RNTSVNRVYISQPDFKTINTRLTNLMEEV---------RTSMDLQQYFGLSSSVAKHTAEQLTEL 244
            .|...|.:||:|.:| .:.||...:..|.         ...:.|::|.|:...:|:..|:::.|.
  Fly   189 ANNQKNIIYINQQEF-PLKTRSMYMDNETAIYRQNYQNNIQLILEKYLGVKDELARKAAKEMFEF 252

  Fly   245 ERTFSSG---GSGAATLQESLSLYTVADLQEKYSDHLNFTEFLGLILGEENIPKSLYIYDEEYLD 306
            |...:.|   .:....|::.:.|.|||:|:|:|:..|:..:.:.:.:||: |...:|.|:..|..
  Fly   253 EVDLAHGLVDNNKHLNLRDLIELLTVAELRERYAPTLDTDQLIFVSMGEK-ISDKVYEYNRRYQQ 316

  Fly   307 KALLTMRSTPLATQANYVLWKLLEDFL-----VDAQPKDMVKWCTESTKKYFGKLAEHAVYKRYR 366
            ..:..:..||.:|.|||:..:|:.:|:     |..:|.:.   |.:.||.||.|..::.:|:||:
  Fly   317 NLVEVIERTPKSTVANYLFLRLIWEFIQKPSGVAEKPTEA---CVDFTKTYFAKNLDNMIYRRYK 378

  Fly   367 NPDVESEVHKIWDQIKGIFRQRLLGD-KLDWISNATRTLAIEKLERMHLNINSYDEENFENVYGE 430
            |.....|:..:|.|:|..|::.||.. .||||..:||:|||.|||.|.|.:|:|.:|||...:.:
  Fly   379 NEKSSREIDSMWHQLKSTFKETLLSSPALDWIEPSTRSLAIAKLEAMTLEVNNYVKENFTEEFAD 443

  Fly   431 VFIDRLNYVSNVQ--QLLIAKGIRFVARINQPADSVDATELLGFTPAYNIQENNITIPVALLQPR 493
            :.:...:.|.|::  |:|.||.:|.:  .:|||..::|.|||.:||:..:.||:|.:|||||||.
  Fly   444 LNLQNTDCVENLRQVQMLQAKQMRQL--YHQPAKPLEAGELLSYTPSNILLENSIKVPVALLQPF 506

  Fly   494 YFWGDQYPEALKYATLGYLLAHEMLHGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYH 558
            |.|.|.||.|:.:.||.||:.||::|||||.||::|..||...|||.||...|.:||.||..||.
  Fly   507 YIWSDVYPNAVMFGTLAYLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYG 571

  Fly   559 EYQYGGSKLPESKDQSENIADSGGLKLAYAAYELWLGQQ-----SEEVLQRETMEGLPFNSRQLF 618
            .|.|.|.:|.||..|||||||:||::|||.||..|...|     ..:.:.:||:..|.:.::|||
  Fly   572 RYVYDGIQLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLF 636

  Fly   619 FLGYAQLLCDDVQFLFQPWVSQSDRHAPSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682
            |:.:||..|:||....:.....:|.|.|.|:||||.||||:||...|||...:.|:|..||.:|
  Fly   637 FISFAQSWCNDVHPKVKALQVSTDDHMPGKFRVIGTLSNFEEFSKEFNCHAGSAMNPIEKCILY 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	240/656 (37%)
		M13	58..679	CDD:189000	237/649 (37%)
Nepl20	NP_651645.1	PepO	50..691	CDD:226118	236/649 (36%)
		M13	56..697	CDD:189000	237/649 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451239
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	1	1.000	-	-		FOG0007609
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850