Protein Alignment Nepl18 and Nepl15

DIOPT Version :9

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Alignment Length: 703
• Identity: 218/703 - (31%)
• Similarity: 356/703 - (50%)
• Gaps: 39/703 - (5%)

  Fly     2 MTSRVLWLCLLVAIVPAMAKPSDAGDPFADDLTSDYAKKIIVQAKVAEMKTMMKPE-VSPCDDFY 65
            |.|:.|.| ||.||:.::. ..||..|  ..|.::|:..|:..||.|.:|..|..| ...|::||
  Fly     1 MASQPLGL-LLGAILFSIC-AIDASVP--HPLAANYSIDILRLAKAAHIKAYMGDEKEQACNNFY 61

  Fly    66 THACGNWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLLRA--NDLQSELEKKMQRFYMSCNLVH 128
            .:||.||.|.:||: .....|:..:.:.:.:.|:...:|::  ...::..:::::.||.||.|..
  Fly    62 NYACANWPRLHPAR-KSKTRTNYLEELQELYIRKSADMLKSATRGAENSADRQLKYFYGSCRLQT 125

  Fly   129 RDDVHYKLALENVIREYGTLPALVGAQWNSSDFSWWRTVAQIQHKYGKQIIIGLEIMHDIRNTSV 193
            .|.......|:||....|..|.:..|.|...::.|.:.||.::.|.|..|.||||::.|.:...:
  Fly   126 NDTRSALNTLQNVTDFRGGWPEIRVASWYQYEYDWLQVVANLKRKLGVDIFIGLEVILDYKEEKM 190

  Fly   194 NRVYISQPDFKT-----INTRLTNLMEEVRTSMD--LQQYF-GLSSSVAKHTAEQLTELERTFSS 250
            :|:.|..|.|..     ::.......|....|::  |:.|| ..|....:..|.|:.::|:..:.
  Fly   191 HRLKIGAPQFPMSRRHYLHPHFEGTREIYERSIENKLKLYFPEQSEHWRQEVASQVVQIEQQLAK 255

  Fly   251 G--GSGAATLQESLSLYTVADLQEKYSDHLNFTEFLGLILGEENIPKSLYIYDEEYLDKALLTMR 313
            |  .:.|.||.::....|.|:::..|..:::.|.:|.||. .:|:...||...|:|:...:..:|
  Fly   256 GLPHNPALTLAQTTRQRTAAEMKTAYGSYVDVTRYLQLIF-NDNLYMDLYETPEDYMSNLVDVIR 319

  Fly   314 STPLATQANYVLWKLLEDFLVDAQPKDMVK--WCTESTKKYFGKLAEHAVYKRYRNPDVESEVHK 376
            .||....|||.:||.||...:...|.....  ||.:..:::|....|...::.|.:..:.:|:..
  Fly   320 ETPKLQLANYTMWKALEALDIARVPASQRADIWCVQLAQQFFPHQLESLFHRNYNHMQMINELQS 384

  Fly   377 IWDQIKGIFRQRL-LGDKLDWISNATRTLAIEKLERMHLNINSYDEEN-FENVYGEVF-IDRLNY 438
            .|..||.:||:.| ..::|.|::..||..||.|||.:.|:..::|:.. ...::|.:. :||  :
  Fly   385 TWSDIKRVFREDLQASERLLWLTLETRQKAITKLEALKLHFRTHDDNKLIRQMHGLILNMDR--F 447

  Fly   439 VSNVQQLLIAKGIRFVARI-NQPADSVDATELLGFTPAYNIQENNITIPVALLQPRYFWGDQYPE 502
            ..|:..:|..|..|.:|:: .:|....:..:|    |.|.||:|.|.:|:..||.|:||...||.
  Fly   448 YPNLVSVLQWKTQRGLAKLMTEPVAEDEVHKL----PHYEIQKNRIQVPITFLQARFFWDPAYPN 508

  Fly   503 ALKYATLGYLLAHEMLHGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEY-QYGGSK 566
            .|||||||.|||.:||||||..||:|||.|....|||..|...:..|.:|||.||..: :|.|..
  Fly   509 GLKYATLGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIFVEYKGKP 573

  Fly   567 LPESKDQSENIADSGGLKLAYAAYELWLGQQSEE--VLQRETMEGLPFNSRQLFFLGYAQLLCDD 629
            :.:.......:||:|.|.:||.||:.||...:|.  :.|||.:..|..:..|:|:||||||.|.|
  Fly   574 VQDKDLLRRIVADNGALDIAYRAYQQWLKNAAETPVIYQRERLPLLDHDHNQIFYLGYAQLYCTD 638

  Fly   630 VQFLFQPWVSQSDRHAPSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682
                :...|.:.| ..|.:.||...|||.|:|...:.||:...::..:||.:|
  Fly   639 ----YPETVERFD-ELPEQLRVNTALSNSQQFANAYGCSREEKLNARFKCTLY 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	199/649 (31%)
		M13	58..679	CDD:189000	195/641 (30%)
Nepl15	NP_651098.2	M13	57..684	CDD:189000	196/639 (31%)
		PepO	57..677	CDD:226118	195/632 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451245
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	1	1.000	-	-		FOG0007609
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850