Protein Alignment Nepl18 and Nepl13

DIOPT Version :10

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 724
• Identity: 177/724 - (24%)
• Similarity: 319/724 - (44%)
• Gaps: 104/724 - (14%)

  Fly    36 DYAKKIIVQAKVA-EMKTMMKPEVSPCDDFYTHACGNWHRHNPAQLLGDVMTDNFKLISKGFDRR 99
            |..::.:|:.|:| :::..|.....||.||:.:|||.|.|::..||..|.::...:|:......:
  Fly    45 DSREEQLVRQKIATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDELSTAQQLMETKISEQ 109

  Fly   100 LQRLLRA-----------NDLQSELEKKMQRFYMSCNLVHRDDVHYKLALENVIREYGTLPALVG 153
            ||:||..           :.......:|::.||.||..|..:....:..|..::::.|.|..:..
  Fly   110 LQQLLTQPLPPQHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLMKILKDNGGLRNVPN 174

  Fly   154 AQWNSSDFSWWRTVAQIQHKYGKQIIIGLEIMHDIRNTSVNRVYISQPDF--------KTINTRL 210
            :.|..:. .|.:|:.:::..||..|::||||..:::....|.:|..:|..        ..:.||.
  Fly   175 SNWQHNR-QWVQTLGELRRNYGLDILLGLEIDLNLQTMKGNTIYFGEPKLTIIPAEHCNALATRG 238

  Fly   211 TNLMEEV------RTSMDLQQYFGLSSSVA---------------KHTAEQ-LTELERTFSSG-- 251
            ..:.:||      :.:.:|:.:||:.:..|               |...|| :.:.|..|...
  Fly   239 AQVRDEVYELVQQQVTENLRDWFGMDTGEAARFAGDIIRFEFELCKQMGEQDIQKPEEEFPPAIQ 303

  Fly   252 ----GSGAATLQESLSL----YTVADLQEKYSDHLNFTEFLGLILGEENIPKSLYIYDEEYLDKA 308
                |:.:.|.||.|..    .|:.:|..:..:||:|...:.:|| |...|..:|:...||:...
  Fly   304 AQIYGARSRTGQERLRRQKGGMTLTELTSEMGNHLDFKMLVEVIL-ESQYPSQVYLRSPEYVKHV 367

  Fly   309 LLTMRSTPLATQANYVLWKLLEDF--LVDAQPKDMVKWCTESTKKYFGKLAEHAVYKRYRNPDVE 371
            :.|:::....|...|:|:..|.:.  ..:..|....:.|.:.|::.|.::......:..:..:.:
  Fly   368 VRTVKANNRITVGGYILYVALNELNQPPEEAPSQRARQCVQVTQRLFPQVLGEMFQRHVQRDNAK 432

  Fly   372 SEVHKIW-DQIKGIFRQRLLGDKLDWISNATRTLAIEKLERMHLNINSYDE--------ENFENV 427
            .::..:: |.||.:..|    ..::|:....|..|..:|.:..:::..|..        :..|:.
  Fly   433 HDLDAVFNDVIKALEEQ----FHVEWMDENDRRAARTRLSQYRVSLPDYQSLDLTDLQFQKSEDY 493

  Fly   428 YGEVFIDRLNYVSNVQQLLIAKGIRFVARINQPADSVDATELLGFTPAYNIQENNITIPVALLQP 492
            :..:.| .|.|.|: ||....:|..|    .|.||.:||.|:   ..|.:.::..:.:...|||.
  Fly   494 WRRLEI-ALKYRSH-QQFEALRGNDF----GQDADGLDAFEV---RAALSPRQQMVLVGWGLLQA 549

  Fly   493 RYFWGDQYPEALKYATLGYLLAHEMLHGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQY 557
            .|: ...||::||||.||:.||..::..|||:|  ::........|:..:...:....:|.:|||
  Fly   550 PYY-NYYYPKSLKYALLGHRLASALVQAFDDEG--WNNHPQATAQWNEVTMSGYRNASECQRAQY 611

  Fly   558 HEYQYG-GSKLPESKDQSENIADSGGLKLAYAAYELWLGQQSEE---VLQRETMEGLPFNSRQLF 618
            ..|.|. ..:...:....|.|||..||.||:.||..||.||..:   :|.:||:..|.|.:.|||
  Fly   612 SSYLYNEPGEFRNATRLREIIADGSGLNLAFNAYLAWLEQQDHKLRPLLAKETLSELNFTNTQLF 676

  Fly   619 FLGYAQLLCDDVQFLFQPWVSQSD----------RHAPSKYRVIGPLSNFQEFPWVFNCSQSAPM 673
            |:.:||..|         |...:.          :|.|.::.|.|||||..||...|.|:...||
  Fly   677 FIYFAQTRC---------WAKDNQDAILDSMPLMQHTPERWDVNGPLSNSAEFGREFGCALGTPM 732

  Fly   674 DPEYKCAIY 682
            :...||.:|
  Fly   733 NSGDKCLVY 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	M13	58..679	CDD:341056	169/696 (24%)
Nepl13	NP_651096.1	M13	68..738	CDD:341056	169/696 (24%)