Protein Alignment Nepl18 and Ece2

DIOPT Version :10

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_038944493.2
• Gene: Ece2 / 408243
• RGDID: 1303039
• Length: 789
• Species: Rattus norvegicus
• Alignment Length: 644
• Identity: 166/644 - (25%)
• Similarity: 282/644 - (43%)
• Gaps: 96/644 - (14%)

  Fly    41 IIVQAKVAEMKTMMKPEVSPCDDFYTHACGNWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLLR 105
            |.|..|:.|   .:...||||.|||..:||.|.|.||.. .|....:.|..:.......|:.||.
  Rat   178 IRVAGKILE---SLDRGVSPCQDFYQFSCGGWIRRNPLP-SGRSRWNTFNSLWDQNQAILKHLLE 238

  Fly   106 AN--DLQSELEKKMQRFYMSCNLVHRDDVHYKLA---LENVIREYG----TLPALVGAQWNSSDF 161
            .:  :..||.|:|.:.||:||  :|.:.:. ||.   |:::|.:.|    |.|      |:..:|
  Rat   239 NSTFNSSSEAERKTRSFYLSC--LHLERIE-KLGAKPLQDLIDKIGGWNITGP------WDEDNF 294

  Fly   162 SWWRTVAQIQHKYGKQIIIGLEIMHDIRNTSVNRVYISQP-------DF---KTINTRLTNLMEE 216
              ...:..:...|.......:.:..|.::::.|.:.:.|.       |:   :|.|.::  |...
  Rat   295 --MEVLKAVAGTYRAAPFFTVYVGADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKV--LAAY 355

  Fly   217 VRTSMDLQQYFGLSSSVAKHTAEQLTELERTFSSGGSGAATLQESLSLY---TVADLQEKYSDHL 278
            :...::|....|...:..:...:|:.|||...::........::...:|   ::::|| ..:..:
  Rat   356 LDYMVELGMLLGGQPTSTRAQMQQVLELEIQLATITVPQDQRRDEEKIYHKMSISELQ-TLAPSM 419

  Fly   279 NFTEFLGLILGEENIPKS--LYIYDEEYLDKALLTMRSTPLATQANYVLWKL-------LEDFLV 334
            ::.|||..:|....:..|  :.:|..|||.:....:..|..:...||::|.|       |:....
  Rat   420 DWLEFLSFLLSPLELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFE 484

  Fly   335 DAQPKDM-----------VKW--CTESTKK----YFGKLAEHAVYKRYRNPDVESEVHKIWDQIK 382
            .||.|.:           .:|  |..:|..    ..|.|...|.:.|......|..:    .:|:
  Rat   485 TAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMI----SEIR 545

  Fly   383 GIFRQRLLGDKLDWISNATRTLAIEKLERMHLNINSYD----EENFENVYGEVFIDRLNYVSNVQ 443
            ..|.:.|  :.|.|:...||..|.||.:.::..|...|    ....::||....:...::..|:.
  Rat   546 AAFEETL--ENLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPRELDDVYDGYEVSEDSFFQNML 608

  Fly   444 QLLIAKGIRFVARINQPADSV---DATELLGFTP----AYNI-QENNITIPVALLQPRYFWGDQY 500
            .|     ..|.|::  .||.:   .:.:....||    ||.: .:|.|..|..:||.. |:...:
  Rat   609 NL-----YNFSAKV--MADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAP-FYAHNH 665

  Fly   501 PEALKYATLGYLLAHEMLHGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEYQYGGS 565
            |:||.:..:|.::.||:.|.|||.||:||..|||.|||..:|...|:....|.:.||::||..|.
  Rat   666 PKALNFGGIGVVMGHELTHAFDDQGREYDQEGNLRPWWQNESLTAFQNHTACMEEQYNQYQVNGE 730

  Fly   566 KLPESKDQSENIADSGGLKLAYAAYELWLGQQSEEVLQRETMEGLPFNSRQLFFLGYAQ 624
            :|...:...|||||:||||.||.||:.||.:..||    :.:..:...:.||||:|:||
  Rat   731 RLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEE----QPLPAVGLTNHQLFFVGFAQ 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	M13	58..679	CDD:341056	162/627 (26%)
Ece2	XP_038944493.2	None