Protein Alignment Nepl18 and Nepl10

DIOPT Version :9

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 732
• Identity: 167/732 - (22%)
• Similarity: 276/732 - (37%)
• Gaps: 173/732 - (23%)

  Fly     6 VLWLCLLVAIVPAMAKPSDAGDPFADDLTSDYAKKIIVQAKVA---EMKTMMKPEVSPCDDFYTH 67
            :|..||:...:|..|                     ||...||   ::...:....|||.:|:..
  Fly     6 LLCSCLVALFIPIQA---------------------IVDINVATSNDIHNNLNRTTSPCTNFWNF 49

  Fly    68 ACGNWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLLRA----ND-LQSELEKKMQRFYMSCNLV 127
            |||.:..       .....|||:.:...|...:...:.:    || |...|.|:|:::|.:|.
  Fly    50 ACGRFSS-------ASKYVDNFERVEDQFATAMVEFMESHLGENDTLAPRLIKQMRQYYKACK-- 105

  Fly   128 HRDDVHYKLALENVIREYGT-LPALVGAQWNSSDFSWWRTVAQIQHKYGKQIIIGLEIMHDIRNT 191
                       |:..:.:|. .|..:..||             |.|. .|.::.||
  Fly   106 -----------EDTRKLHGNPRPEELVNQW-------------ILHP-KKFLVYGL--------- 136

  Fly   192 SVNRVYISQPDFKTINTRLTNLMEEVRTSMDLQQYFGLSSSVAKHTAEQLTELERTFSSG--GSG 254
              |.|:|.:......|       :.:|..:.|:    :.....:::..::.:|.|.:...  ..|
  Fly   137 --NGVFIDERVDVAAN-------DSMRWVIQLR----MPDPADRYSDRRVLQLMRLYEEAWYSMG 188

  Fly   255 AATLQESLSLYTVADLQEKYS--------------------DHLNFTEFLGLILGEENIPKSLYI 299
            ...|.|.:.     .||:||.                    .|..|.|.||:...||....:..:
  Fly   189 VVKLVEKMH-----QLQDKYRAEYPVVYTWSFSELRQEIPIPHSFFIELLGVNHTEELYHLTFEV 248

  Fly   300 YDEEYLDKALLTMR---STPLATQANYVLWKLLEDFLVDAQPKDM-VKWCTESTKKYFGKLAEHA 360
            .|.|||.:....:|   |.|..|......:.|:|    :::|::. .:.|....:.|. .|..:.
  Fly   249 SDVEYLRECFRCLRDFASEPKDTYIRARQYVLVE----ESEPRERNPRSCIHHMRAYL-PLGMNY 308

  Fly   361 VYKR--YRNPDVE-SEVHKIWDQIKGIFRQRLLGDKLDWISNATRTLAIEKLERMHLNINSYDEE 422
            :|.|  |:|.:.: |:|.:|...:|..|.|.|..::|....|....:. .|||.:.:.|.:..||
  Fly   309 IYDRFIYQNREEDTSKVLEILSTLKAAFGQYLDANRLQLTPNQLAYVR-AKLEGIQIKIGNLPEE 372

  Fly   423 N----FENVYGEVFIDRLNYVSNVQQL-----------LIAKGIRFVARINQPADSVDATELLGF 472
            .    :.|.||.......|:::|:.:.           |:|:..|...|.....|:|.....
  Fly   373 KSPEFYNNHYGSANFSATNFLANLLEAFALRTRLQNAGLLARNSRVDLRHYYVNDNVRKART--- 434

  Fly   473 TPAYNIQENNITIPVALLQPRYFWGDQYPEAL-KYATLGYLLAHEMLHGFDDDGRQYDASGNLAP 536
            :|.|..:.|.||:|:..||...|  |.....: :::.||.:|.|||.|.|:.:|..:||:||.:|
  Fly   435 SPFYENERNTITVPMEFLQWPLF--DHREHTIFQHSLLGAVLGHEMNHAFEQEGILFDAAGNESP 497

  Fly   537 -WWDLKSRYEFEERRKCFQAQYHEYQYGGSKLPESKDQSENIADSGGLKLAYAAYELWLGQQSEE 600
             ..:::....|.:..||.:.|            ......|.:||..||:|||.|: ..|...|.:
  Fly   498 VGLEIRESKPFRDAIKCAEEQ------------PFVSLKERLADLNGLQLAYDAF-FGLAHDSRQ 549

  Fly   601 VLQRETMEGLPFNSRQLFFLGYAQLLCDDVQFLFQPWVSQSDRHAPSKYRVIGPLSNFQEFPWVF 665
            ...|.......|.:.|||.|.|||..|..:     |.|...||   ...||...:.|.::|.:.|
  Fly   550 FEYRPYAFEQEFTAPQLFHLSYAQFFCGSL-----PPVIAHDR---DDERVNVSVGNLRQFAYDF 606

  Fly   666 NCSQSAPMDPEYKCAIY 682
            ||..|    |...|.::
  Fly   607 NCETS----PSSVCEMW 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	158/679 (23%)
		M13	58..679	CDD:189000	157/672 (23%)
Nepl10	NP_610787.1	GluZincin	41..608	CDD:301352	153/659 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920