Protein Alignment Nepl18 and Nepl9

DIOPT Version :10

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 720
• Identity: 151/720 - (20%)
• Similarity: 258/720 - (35%)
• Gaps: 200/720 - (27%)

  Fly    42 IVQAKVAEMKTMMKPEVSPCDDFYTHACGNWHRHN--------PAQLLGDVMTDNFKLISKG-FD 97
            :.::.:.::..:....:.||||||.|||||:.:..        |..|.......||.....| |:
  Fly    45 LYKSNLQQLVKIKNDSMDPCDDFYAHACGNFDQTKEENSDDFLPPYLYNKQDRMNFFTAEVGNFE 109

  Fly    98 RRLQRLLRANDLQSELEKKMQRFYMSCNLVHRDDVHYKLALENVIREYGTLPAL-----VGAQWN 157
            ....||:  :.|.:|..|:.:|...:..   |...|::..|:.:       |.|     |.:.|.
  Fly   110 TIPGRLI--SQLYTECRKREERNVFTPT---RLTSHWERMLDEI-------PFLARHKEVLSSWP 162

  Fly   158 SSDFSWWRTVAQIQHKYGK--QIIIGLEI-MHDIRNT-----SVNRVYISQ------PDFKTINT 208
            .....|.|     :..||:  .|::..:: .|.:...     :::.:|:|.      |......:
  Fly   163 FLKHQWER-----RRLYGQLNWIVLSAQLAAHGLPTLLHIYFALDTIYVSPMEELPCPSIADFQS 222

  Fly   209 RLTNLME-------------------EVRTSMDLQQYFGLSSSVAKHTA----EQLTELERTFSS 250
            .|::::|                   |:|..:.|.:  .||.:...:|:    |||...|.|.
  Fly   223 SLSDVLEGRHHQVSRIISHEMRVLCREMRGELPLVR--SLSQNTRTNTSRPGEEQLLLDENTM-- 283

  Fly   251 GGSGAATLQESLSLYTVADLQEKYSDHLNFTEFLGLILGEENIPKSLYIYDEEYLDKALLTMRST 315
                              |..::|...|||:|  ..::|....|     .|.|.:.:|...:|.|
  Fly   284 ------------------DYFQQYFAALNFSE--ERLVGARKFP-----LDVEKITQAWEVLRHT 323

  Fly   316 PLATQANYVLWKLLEDFLVDAQPKDMVKW--CTESTKKYFGKLAEHAVYKRYR--NPDVESEVHK 376
            ......|||:|          |.::.:::  |...::::...|  ||.|.::.  ...:..||..
  Fly   324 ETRIVYNYVMW----------QAREQLRYPDCYRVSEEFERLL--HAEYWQWHVLRRHLSREVAL 376

  Fly   377 IWDQIKGIFRQRLLGDKL---DWISNATRTLAIEKLERMHLNINSYDEENFENV------YGEVF 432
            ...|:.....|:|...||   ||..:.. ..::||.|.....|.....||:.|:      |..:.
  Fly   377 ASYQLHTTRFQKLRRSKLSRRDWYGHLW-PASVEKKELQVARILQNHAENYLNITELNENYEGLK 440

  Fly   433 IDRLNYVSNVQQLLIAKGIRFVARINQP-ADSVDATELLGFTPAYNIQENNITIPVALLQPRYFW 496
            :::.::.:|   |||.:..:.......| .|..|..:     |||.::.....:.::|.:|.|.:
  Fly   441 LEKNSFYAN---LLILRRAQLRHSFVSPYVDEEDVNQ-----PAYFLRHFLHFVLLSLHRPTYHY 497

  Fly   497 GDQYPEALKYATLGYLLAHEMLHGFDDDG-------------RQYDASGNLAPWWDLKSRYEFEE 548
                     |||.|..|..|.....|.||             :.|||  .|||.:.....:|..|
  Fly   498 ---------YATHGLELWRESRLLLDTDGHYTAMDCLERQSFQHYDA--KLAPIYRPLGSHEIAE 551

  Fly   549 RRKCFQAQYHEYQYGGSKLPESKDQSENIADSGGLKLAYAAYELWLGQQSEEVLQRET--MEGLP 611
               .||. |..:||             ::.|          |..||  |.|.....||  ::...
  Fly   552 ---IFQF-YRSFQY-------------SLTD----------YHFWL--QGERFAFAETFVLDYFG 587

  Fly   612 FNSRQLFFLGYAQLLCDDVQFLFQPWVSQSDRHAPSKYRVIGPLSNFQEFPWVFNCSQSAPMDPE 676
            .|..::.|...||.||:....:|...:::.             ..|..||...|.|.....|:|.
  Fly   588 LNPHRVLFYAVAQQLCNRQTEIFAAQLNRG-------------YMNLPEFQEAFKCGAEKAMNPP 639

  Fly   677 YKCAI 681
            .:|.|
  Fly   640 SRCMI 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	M13	58..679	CDD:341056	149/700 (21%)
Nepl9	NP_609815.1	GluZincin	62..642	CDD:472708	149/699 (21%)